Equus caballus (horse): 100034046
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Entry
100034046 CDS
T01058
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00120
Primary bile acid biosynthesis
ecb01040
Biosynthesis of unsaturated fatty acids
ecb01100
Metabolic pathways
ecb01212
Fatty acid metabolism
ecb04146
Peroxisome
Module
ecb_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
ecb_M00861
beta-Oxidation, peroxisome, VLCFA
ecb_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
100034046 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
100034046 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100034046 (HSD17B4)
Enzymes [BR:
ecb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
100034046 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
100034046 (HSD17B4)
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Gene cluster
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
adh_short
MaoC_dehydratas
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
AbrB-like
HerA_C
Motif
Other DBs
NCBI-GeneID:
100034046
NCBI-ProteinID:
NP_001075370
Ensembl:
ENSECAG00000017805
VGNC:
18887
UniProt:
Q6RFZ6
LinkDB
All DBs
Position
14:complement(53031919..53113188)
Genome browser
AA seq
735 aa
AA seq
DB search
MASQLRFDGRVVLVTGAGGGLGRAYALAFGERGASVVVNDLGGDMKGVGKSSLAADKVVE
EIRSRGGKAVASYDSVEAGEKIVKTALDAFGRIDVVVNNAGILRDRSFGRLSDEDWDIIH
RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYSAAKLGLLGLSNTLAI
EGKKNNIHCNTIAPQAGSRLTQTVFPEDVVEALKPDYVAPLVLWLCHESCEENGSLFEVG
AGWIGKLRWERTLGALVRQRNQPMTPEAVKANWKKICDFGSVSNPQTIQESTGGIIGLVS
KMDSNGGVSTNHTSHAASTATSGFVGAIGQKLPSFSSTYTELEAIMYALGVGASIKEPKD
MKFIYEGSSDFSCLPTFGVITAQKSMLGELAQIPGLSLDFAKVLHGEQYLELYKPLPRTG
KLKCEGVVADILDKGSGVVILLDVYSYSGNELLCYNQFSLFLVGSGGFGGKRTSDKMKVA
VAVPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPNFSSLAGFDKPILHGLCTFGFSA
RHVLQQFADHDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISNA
YVDLVPTSDMLAKTPSKGGELQSTLVFEEIGRRLKDIGHQVVKTVNAVFEWHITEGGNTA
ATWTIDLKNGSGEVYQGPARGSADTTLTLSDEHFMEVVQGKLDPQKAFFSGKLKAKGNIM
VSQKLQKILKDYAKL
NT seq
2208 nt
NT seq
+upstream
nt +downstream
nt
atggcctcacagctgagattcgacgggcgggtcgtactggtcaccggcgcggggggagga
ctgggccgagcctatgccctggcttttggagaaagaggtgcgtcagttgttgtgaatgat
ttaggaggggacatgaagggagttggtaaaagctccttagccgctgataaggttgttgaa
gaaataagaagcagaggcggaaaagcagtggccagctatgattcagtggaagcaggagag
aagattgtgaagacagccttggatgcgtttggaagaatagatgttgtggtcaacaatgct
ggaattctgagggaccgttcctttggtagactaagtgatgaagactgggatataatccat
agagttcatttgcggggctcctttctagtgacccgggcagcgtgggatcacatgaagaaa
cagaagtttggaaggatcattatgacttcgtcagcttcgggaatatatggcaactttggc
caggcaaattatagtgctgcaaagctgggtcttctgggcctttcaaatactcttgcaatt
gaaggcaagaaaaataacattcattgtaacactattgcccctcaagctggatcacggttg
acccagactgtttttcctgaggatgttgtagaagctttgaagccagattacgtggccccc
ctggtcctttggctttgtcacgaaagttgtgaggaaaatggtagcttgtttgaggttgga
gcaggatggattggaaaattacgctgggagcggacccttggagcccttgtaagacagagg
aatcagccaatgactcctgaggcagtgaaggcgaactggaagaagatctgtgactttggt
agtgtcagcaatcctcagacaattcaagaatcaactggcggtataattggacttgtaagt
aaaatggattccaatggaggagtttcaacaaatcataccagtcatgcggcatcaacggcc
acatcaggatttgttggagctattggccagaaacttccttcattttcttccacttatacg
gaactggaagctattatgtatgcccttggagtgggagcatcaatcaaggaaccaaaagat
atgaaatttatttatgaaggaagttctgatttctcctgtttgcctacctttggagttatt
acagctcagaaatctatgcttggagaattagcacagattcctgggctttcactcgacttt
gcgaaggttcttcatggagagcaatacttggagttatataagccacttcccagaacggga
aaattaaaatgtgaaggggttgttgctgatatcctagataaaggatccggtgtagtaatt
cttctggatgtttattcttattctggaaacgaacttctgtgttataatcagttctcactc
ttccttgttggctctggaggctttggtggaaaacggacgtcagacaaaatgaaggtagcg
gtagccgtacctaacagacctcctgatgctatacttacagacaccacctcacttaatcag
gctgctttgtaccgcctcagtggagactggaatcccttacacattgatcctaacttctct
agcttagcaggttttgacaagccaatattacatggattgtgtacatttggattttctgcc
aggcatgttttacagcagtttgcagatcacgatgtgtcaagattcaaggcaattaaggct
cgttttgcaaaaccagtatatccaggacaaactctacaaactgagatgtggaaggaagga
aatagaatccatttccaaaccaagatccaagaaactggagacatcgtcatttcaaatgca
tatgtggatcttgtgccaacatctgatatgttagctaagacaccctctaagggtggggag
cttcagagtacccttgtttttgaggaaataggtcgccgccttaaggatattgggcaccag
gtggtaaagacagtaaacgctgtatttgagtggcatatcactgaaggtggaaataccgca
gctacgtggactattgacctgaaaaatggttctggagaagtgtatcaaggccctgcaaga
ggctctgctgacacaaccttgacactttcagatgagcatttcatggaggtagtccagggc
aagcttgatcctcagaaggcattctttagtggcaaactgaaggccaaagggaacatcatg
gtgagccagaagcttcagaagattctgaaagactacgccaagctctga
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