Equus caballus (horse): 100034196 Help Entry 100034196         CDS       T01058                                  Symbol IL6 Name (RefSeq) interleukin-6 precursor   KO K05405   interleukin 6 Organism ecb  Equus caballus (horse) Pathway ecb01521   EGFR tyrosine kinase inhibitor resistance ecb01523   Antifolate resistance ecb04060   Cytokine-cytokine receptor interaction ecb04061   Viral protein interaction with cytokine and cytokine receptor ecb04066   HIF-1 signaling pathway ecb04068   FoxO signaling pathway ecb04151   PI3K-Akt signaling pathway ecb04218   Cellular senescence ecb04620   Toll-like receptor signaling pathway ecb04621   NOD-like receptor signaling pathway ecb04623   Cytosolic DNA-sensing pathway ecb04625   C-type lectin receptor signaling pathway ecb04630   JAK-STAT signaling pathway ecb04640   Hematopoietic cell lineage ecb04657   IL-17 signaling pathway ecb04659   Th17 cell differentiation ecb04668   TNF signaling pathway ecb04672   Intestinal immune network for IgA production ecb04931   Insulin resistance ecb04932   Non-alcoholic fatty liver disease ecb04933   AGE-RAGE signaling pathway in diabetic complications ecb04936   Alcoholic liver disease ecb05010   Alzheimer disease ecb05020   Prion disease ecb05022   Pathways of neurodegeneration - multiple diseases ecb05132   Salmonella infection ecb05133   Pertussis ecb05134   Legionellosis ecb05135   Yersinia infection ecb05142   Chagas disease ecb05143   African trypanosomiasis ecb05144   Malaria ecb05146   Amoebiasis ecb05152   Tuberculosis ecb05161   Hepatitis B ecb05162   Measles ecb05163   Human cytomegalovirus infection ecb05164   Influenza A ecb05166   Human T-cell leukemia virus 1 infection ecb05167   Kaposi sarcoma-associated herpesvirus infection ecb05168   Herpes simplex virus 1 infection ecb05169   Epstein-Barr virus infection ecb05171   Coronavirus disease - COVID-19 ecb05200   Pathways in cancer ecb05202   Transcriptional misregulation in cancer ecb05321   Inflammatory bowel disease ecb05323   Rheumatoid arthritis ecb05332   Graft-versus-host disease ecb05410   Hypertrophic cardiomyopathy ecb05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100034196 (IL6)    04668 TNF signaling pathway     100034196 (IL6)    04066 HIF-1 signaling pathway     100034196 (IL6)    04068 FoxO signaling pathway     100034196 (IL6)    04151 PI3K-Akt signaling pathway     100034196 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     100034196 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     100034196 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     100034196 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     100034196 (IL6)    04620 Toll-like receptor signaling pathway     100034196 (IL6)    04621 NOD-like receptor signaling pathway     100034196 (IL6)    04623 Cytosolic DNA-sensing pathway     100034196 (IL6)    04625 C-type lectin receptor signaling pathway     100034196 (IL6)    04659 Th17 cell differentiation     100034196 (IL6)    04657 IL-17 signaling pathway     100034196 (IL6)    04672 Intestinal immune network for IgA production     100034196 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100034196 (IL6)    05202 Transcriptional misregulation in cancer     100034196 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100034196 (IL6)    05161 Hepatitis B     100034196 (IL6)    05171 Coronavirus disease - COVID-19     100034196 (IL6)    05164 Influenza A     100034196 (IL6)    05162 Measles     100034196 (IL6)    05168 Herpes simplex virus 1 infection     100034196 (IL6)    05163 Human cytomegalovirus infection     100034196 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     100034196 (IL6)    05169 Epstein-Barr virus infection     100034196 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     100034196 (IL6)    05135 Yersinia infection     100034196 (IL6)    05133 Pertussis     100034196 (IL6)    05134 Legionellosis     100034196 (IL6)    05152 Tuberculosis     100034196 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     100034196 (IL6)    05144 Malaria     100034196 (IL6)    05142 Chagas disease     100034196 (IL6)    05143 African trypanosomiasis     100034196 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     100034196 (IL6)    05321 Inflammatory bowel disease     100034196 (IL6)    05332 Graft-versus-host disease     100034196 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     100034196 (IL6)    05020 Prion disease     100034196 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     100034196 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100034196 (IL6)    05410 Hypertrophic cardiomyopathy     100034196 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100034196 (IL6)    04932 Non-alcoholic fatty liver disease     100034196 (IL6)    04931 Insulin resistance     100034196 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     100034196 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100034196 (IL6)    01523 Antifolate resistance     100034196 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:ecb04052]     100034196 (IL6) Cytokines and neuropeptides [BR:ecb04052]  Cytokines   Interleukins    100034196 (IL6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL6 GCSF IL23 Sec16 Motif Other DBs NCBI-GeneID:  100034196 NCBI-ProteinID:  NP_001075965 Ensembl:  ENSECAG00000016482 VGNC:  52396 UniProt:  Q95181 LinkDB All DBs Position 4:54607522..54611577 Genome browser AA seq 208 aa AA seqDB search MNSLFTSTVTPVAFSLGLLLVMATAFPTPLPLGEDETTSNGPLLTTADKTKQHIKYILGK ISALKNEMCNNFSKCENSKEVLAENNLNLPKMAEKDGCFQSGFNQETCLMKITTGLSEFQ IYLEYLQNEFKGEKENIKTMQISTKVLVQILMQKMKNPEVTTPDPTAKSSLLAKLHSQNE WLKNTTTHLILRSLEDFLQFSLRAVRIM NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atgaactccctcttcacaagcaccgtcactccagttgccttctccctggggctgctcctg gtgatggctactgctttccccaccccactacccctgggagaagatgaaaccacctcaaat ggaccactactcaccactgcagacaaaaccaaacagcacattaagtacatcctcggcaaa atctctgccctgaaaaatgagatgtgtaacaattttagcaagtgtgaaaacagcaaggag gtactggcagaaaacaacctgaatcttccaaagatggcagaaaaagacggatgcttccaa tctgggttcaatcaggagacctgcctgatgaaaatcaccactggtctttcggagtttcag atatacctggagtacctccagaacgagttcaagggtgaaaaggaaaacatcaagactatg cagatcagtaccaaagtcctggtccagatcctgatgcaaaagatgaagaatccagaagta accacccctgacccaactgcaaaaagcagcctgctggctaagctgcattcacagaatgag tggctgaagaacacaacaactcacctcatccttcgaagccttgaggatttcctgcagttc agcctgagagctgttcggataatgtaa

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