Equus caballus (horse): 100058700
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Entry
100058700 CDS
T01058
Symbol
BACE2
Name
(RefSeq) beta-secretase 2 isoform X1
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100058700 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ecb01002
]
100058700 (BACE2)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
100058700 (BACE2)
Peptidases and inhibitors [BR:
ecb01002
]
Aspartic peptidases
Family A1: pepsin family
100058700 (BACE2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
100058700
NCBI-ProteinID:
XP_023485970
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Position
26:38100652..38188688
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AA seq
518 aa
AA seq
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MGALARALLLPLLAQWLLRAAPALAPAPFTLPLRVAVATSRGAAPTPRPGTPSEPRAVPR
ADGLALALEPAGGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
APHAYIDSYFDAERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATI
FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQAKIPNVFSMQMCGAGLPVA
GPGTNGGSLVLGGIEPSLYRGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
IVDSGTTLLRLPQKVFNAVVEAVARTSLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI
YLRAENSSRSFRITILPQLYIQPMMGPGLNYECYRFGISPSTNALVIGATVMEGFYVVFD
RARKRVGFAASPCAEIAGAPVSEISGPFSTDDVASNCVPALPLNEPILWIVSYTLMSVCG
IILLILIILLLVPFRCRHGPRDPEVVNDESSLVRHRWK
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctggcccgggcgctgctgctgccgctgctggcccagtggctcctgcgcgcg
gccccggcgctggcccccgcgcccttcacgctgcccctccgggtggccgtggccactagc
cgcggagctgcgcccacccccaggcccgggaccccctccgagccccgcgccgtgccccgc
gccgacggcctggcgctcgccctggagcccgccgggggcgcggccaacttcttggccatg
gtggacaacctgcaaggggactctggccgcggctactacctggagatgctgatcgggacc
cccccacagaagctgcagattctggttgacactgggagcagcaacttcgccgtggcaggt
gccccgcatgcgtacatagactcctactttgatgccgagaggtccagcacgtaccgctcc
aagggctttgatgtcaccgtgaagtacacacaggggagctggactggcttcgttggggag
gaccttgtcaccatcccaaaaggcttcaatagttcttttcttgtcaacattgccactatt
tttgagtctgagaatttctttttgcctggcattaaatggaacgggatccttggacttgcc
tatgcaaccctggcgaagccatcaagttccctggagacattttttgattccctggtgaca
caagcaaaaatccccaacgttttctccatgcagatgtgtggggcaggattgccagtagct
ggacctggtaccaacggaggtagtcttgtcctgggtggaattgaaccgagtctgtacaga
ggagacatctggtatacccctattaaggaggagtggtattatcagatagaaattctgaaa
ttggaaatcggaggccagagccttaatctggactgcagagagtataatgcggacaaggcc
atcgtggacagtggcaccacactgctgcgcctgccccagaaggtgtttaacgcagtggtc
gaagctgtggcccgcacatctctgattccagaattctctgatggtttctggactgggtcc
cagctggcatgttggacgaattcggagacaccttggtcttacttccctaaaatctccatc
tacctgagagccgagaactccagcaggtcgttccggataactatcctgcctcagctttac
attcagcccatgatggggcctggcctgaattatgaatgttaccgattcggcatttcccct
tccacgaatgcgctggtgattggtgctaccgtgatggagggtttctacgtggtctttgac
agagctcggaagagggtaggctttgcagcaagcccctgtgcagaaattgcaggtgctccg
gtgtctgaaatttctgggcctttctccacagacgatgtagccagcaactgtgtccctgcc
ctgcctttgaatgagcccattttgtggattgtctcctatactcttatgagcgtgtgcgga
atcatccttcttatcttaatcatcctgctgctagttccgttccggtgtcggcatggcccc
cgcgatcccgaggttgtcaatgatgagtcctctctcgtccggcatcgctggaaatga
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