KEGG   Equus caballus (horse): 100064751
Entry
100064751         CDS       T01058                                 
Symbol
MAP3K3
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 3 isoform X1
  KO
K04421  mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04010  MAPK signaling pathway
ecb04722  Neurotrophin signaling pathway
ecb04912  GnRH signaling pathway
ecb05166  Human T-cell leukemia virus 1 infection
ecb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100064751 (MAP3K3)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    100064751 (MAP3K3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100064751 (MAP3K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100064751 (MAP3K3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100064751 (MAP3K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100064751 (MAP3K3)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     100064751 (MAP3K3)
Protein kinases [BR:ecb01001]
 Serine/threonine kinases: STE group
  STE11 family
   100064751 (MAP3K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PB1 ABC1 Kinase-like FTA2
Other DBs
NCBI-GeneID: 100064751
NCBI-ProteinID: XP_023507995
Ensembl: ENSECAG00000008917
VGNC: 19937
LinkDB
Position
11:complement(15645145..15709575)
AA seq 657 aa
MDEQEALNSIMKDLVALQMSRRSRAPGYETMKNKDTGHPNKQKKHNSSSSALLNSPTVTT
GSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVRYEDVEHKVTIVFGQPLDLHYMNNE
LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHTSSSPHSGVSRQVRIKASQSAG
DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQRIARQGSYTSINSEGEFIPETS
EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEFSDRETQLYDKG
VKGGTYPRRYHVSVHHKDYNDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
DPRGRLRSADSENALSVQERSVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLVY
NT seq 1974 nt   +upstreamnt  +downstreamnt
atggacgaacaggaggcattgaactcaatcatgaaggatctggtggccctgcagatgagc
cgacgttcccgagcgcctggatatgagaccatgaagaacaaagacacgggtcacccaaat
aagcagaaaaaacacaacagcagcagctcagcccttctgaacagccccacagtaacaaca
ggctcatgtgcaggggccagtgagaaaaagaaatttttgagtgacgtcagaatcaagttt
gagcacaacggggagaggcgaattatagcgttcagccggcctgtgcgatatgaagatgtg
gagcacaaggtgacaatagtgtttgggcagcctcttgatctacattacatgaacaatgag
ctctccatcctgctaaagaaccaagatgatcttgataaagcaattgacattttggataga
agctcaagcatgaaaagccttaggatattgttgctatcccaggacagaaaccataccagt
tcctctccccactctggggtgtccagacaggtgcggatcaaagcttcccagtctgcagga
gatataaacaccatctaccagccccctgagcccagaagcaggcatctctctgtcagctcc
cagaaccctggccgaagctcacctccccctggctatgtgcctgagcggcagcagcgcatt
gcccgacaggggtcctataccagcatcaacagtgagggagagttcatcccggagaccagc
gagcagtgcatgctggatcccctgagcagtgctgaaaattccttgtcgggaagctgccag
tctttggacaggtcagcagacagtccgtccttccggaaatctcgaatgtcccgagcccag
agcttcccagacaacagacaggagttctcggatcgggaaactcaactctatgacaaaggg
gtcaaaggtggaacctacccccggcgctaccacgtgtctgtgcaccacaaggactacaac
gatggcagaagaacgtttcctcgaatacgacgtcatcaaggtaacctgttcaccctggtg
ccctccagccgctccctgagtacaaatggcgagaacatgggtctagcagtgcaatacctg
gacccccgtgggcgcctgcggagtgcggacagcgagaatgccctctctgtgcaggagagg
agtgtgccaactaagtctcctagtgcccccatcaattggcgccgggggaagctcctgggc
cagggtgccttcggcagggtctatttatgctatgatgtggacacaggacgcgaacttgct
tccaagcaggtccagtttgacccagacagtcctgagacaagcaaggaggtgagtgctctg
gaatgtgagatccagttgctgaagaacttgcagcacgagcgcattgtgcagtactatggc
tgtctgcgggaccgtgccgagaagactctgaccatcttcatggagtacatgccagggggc
tcagtgaaagaccagttgaaggcctacggagctctgacagagagtgtgacccgaaaatac
acccggcagatcctggagggaatgtcctacctgcacagcaacatgattgttcaccgggac
atcaagggagccaacatcctccgagactctgctgggaatgtgaagctgggggactttggg
gccagcaagcgcctgcagaccatctgcatgtcgggcaccggcatgcgctcagtcaccggc
acaccctactggatgagccctgaggtgatcagcggtgagggctacggaaggaaggcagat
gtgtggagcctgggctgtactgtggtggagatgctgacagagaagccaccttgggcagag
tatgaagccatggccgccattttcaagattgccacccagcccaccaatcctcagctgccc
tctcacatctctgagcatggccgggacttcctgaggcgcatttttgtggaggcccgccag
agaccttcagccgaggagctgctcacacaccactttgcacagctcgtgtactga

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