Equus caballus (horse): 100066488
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Entry
100066488 CDS
T01058
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04137
Mitophagy - animal
ecb04140
Autophagy - animal
ecb04141
Protein processing in endoplasmic reticulum
ecb04210
Apoptosis
ecb04932
Non-alcoholic fatty liver disease
ecb05010
Alzheimer disease
ecb05012
Parkinson disease
ecb05014
Amyotrophic lateral sclerosis
ecb05020
Prion disease
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05160
Hepatitis C
ecb05162
Measles
ecb05168
Herpes simplex virus 1 infection
ecb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100066488 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100066488 (EIF2AK3)
04137 Mitophagy - animal
100066488 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
100066488 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
100066488 (EIF2AK3)
05162 Measles
100066488 (EIF2AK3)
05168 Herpes simplex virus 1 infection
100066488 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
100066488 (EIF2AK3)
05012 Parkinson disease
100066488 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
100066488 (EIF2AK3)
05020 Prion disease
100066488 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
100066488 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100066488 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100066488 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100066488 (EIF2AK3)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100066488 (EIF2AK3)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: Other
PEK family [OT]
100066488 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
100066488
NCBI-ProteinID:
XP_023474525
Ensembl:
ENSECAG00000020856
VGNC:
17479
LinkDB
All DBs
Position
15:17909579..17977761
Genome browser
AA seq
1113 aa
AA seq
DB search
MERATRPGPLARALLLLLLGLVAGTVAAGRAPDLPVPTAEAAFGLGAAAAPTSAARVPAA
GSVTAAEVTVEDAEGLPAAAGDQEPQEPEPDDVTELRPRGRSLVIISTLDGRIAALDPEN
HGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVESLL
ESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRRWDNDEMEQEDILLLQRTQK
TVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGSKEESKIISDLEEQEA
AMLDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTSYTS
NNEVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALENVNDENAI
IPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLP
YYKRERNKRSTQITVRFLDNPNYSKTIRKKDPVLLLPWWKEIVATILFCIIATTFIVRRL
FHPHPHRQRKESETQCQTENKYDSLSGEVNDSGSNDVKNSGYVSRYLTDFEPVQCMGRGG
FGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPP
EKWQEEMDEIWLKDESTDWPPSSPSPMDAPSVKIRRMDPFSTKEHIEIIAPSPKRSRSFS
VGISCGQTSSSESQFSPLEFSGTDHGDISGSVDAVYNLQDSCLTDCDVGDGTIDGNDEGH
SFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEELKTNPLHIGNHDADKLTALKHS
SSNSPSEPALSVSPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNSR
CTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKIGDFGLVTAMD
QDEEEQMVLTPMPAYARHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFGT
QMERVRILTDVRNLKFPPLFTQKYPREHVMVQDMLSPSPMERPEATNIIENAVFEDLEFP
GKTVLRQRSRSVSSSGTKPSRQPSNSQSPLPSS
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccgcccggggccgctcgcgcgggcgctgctactgctgctgctgggg
cttgtggcagggacggtggccgcggggcgcgctcccgacctccctgtgccgacggcggag
gcggcgtttggattgggggctgcggccgctcccacctcggccgcgcgggtgccggcggcg
gggtctgtgactgctgcagaggtgacggtggaggacgccgaggggctgccggcggccgca
ggcgaccaggagccgcaggagccggaacccgacgacgtgaccgagctgcggccacgcggc
agatcgttagtgattatcagcactttagatgggcgaattgctgccttggatcctgagaat
catggtaaaaagcagtgggatttggatgtgggatccggttccttggtttcatcaagcctt
agcaaaccagaggtatttgggaataagatgatcattccttccctggatggagacctcttc
cagtgggaccgagaccgtgagagcatggaaacagttccttttaccgttgagtcacttctt
gaatcttcttataaatttggagatgatgttgttttggttggaggaaagtctctcactaca
tatggactcagtgcatatagtggaaaggtgaggtatatctgttcagctttgggttgtcgc
cgatgggataatgatgaaatggaacaagaggacatcctgcttctgcagcgcacccagaaa
accgttcgagctgttggacctcgtagtggcaatgagaagtggaatttcagtgttggccac
tttgaacttcggtatattccagacatggaaactagagccggatttattgaaagcacccta
aaacccagtggaagcaaagaagagtctaaaattatttcagatctggaagaacaggaagct
gccatgttggacacagtgataaaggtctcagttgctgattggaaggttatggcgtttagt
aaaaagggcggacatctggaatgggagtaccagttttgtactcccattgcatctgcctgg
ttggttaaggatggcaaagtcattcccatcagtctttttgatgatacgagttatacatct
aataatgaagttttagaagatgaagaagacattgtggaagctgcccgaggagccacagag
aacagcgtttacttgggaatgtacagaggccagctgtatctgcagtcgtcagtcagaatt
tcagaaaagtttcccacaagccccaaggccttggaaaacgtcaatgatgaaaatgcgatt
atccctttgccaacaatcaaatggaaacccttaattcattctccttccagaactcctgtc
ttggtagggtctgatgaatttgacaaatgtcttagtaatgataagttttctcatgaagag
tacagtaatggagcactttcaatcttgcagtatccatatgataatggttactatctacca
tactacaagagggagaggaacaagcggagcactcagatcacagtcaggtttcttgacaac
ccgaactacagcaagaccatccgcaaaaaggatccggttctcctcttgccctggtggaaa
gaaatagttgcaactattctgttttgtatcatagcaacaacttttatcgtgcgcagactt
ttccatcctcatcctcacaggcaaaggaaagaatctgaaactcagtgtcaaactgaaaat
aaatatgactctttaagtggagaagttaatgacagtggctcgaatgacgtaaaaaattct
ggctacgtatcacggtatctgacagattttgaaccggttcagtgcatgggtcgtggcggg
tttggagttgtctttgaagctaaaaacaaagtagatgactgcaattatgctatcaagaga
atccgtctccccaacagggaattggctcgggaaaaagtaatgcgagaggttaaagcctta
gccaagcttgaacacccaggaattgttagatatttcaatgcttggttggaagcaccacca
gagaagtggcaagaagaaatggacgaaatttggctgaaagatgaaagcacagactggcca
cccagctctcctagcccaatggatgcaccatcagttaaaatacgcagaatggatcctttc
tcaacaaaagaacatattgaaatcatagctccttcgccaaaaaggagcaggtctttttca
gtagggatttcctgtggccagacaagttcatctgagagccagttctctccactggaattt
tcaggaacggaccatggagacatcagtgggtcggtggacgcagtgtacaatctccaagac
agttgccttacagactgtgatgtgggagatggtactatagatggcaatgatgaggggcac
tcctttgaactttgtccttctgaagcttctccttatgtcaggtcaagggagagaacatcc
tcttccatagtatttgaagattctggctgtgataatgcgtccagtaaagaagagctcaaa
actaacccactgcatatcggcaaccatgatgctgataaactgactgctttgaagcattcc
agtagcaactctccttctgaacctgctttatctgtttctcctccaagaccaaccacttta
agtttagatctcactaaaaacactacggaaaaactccagcccagttcgccgaaagtgtat
ctttacattcagatgcagctatgcagaaaggaaaacctcaaagactggatgaacagtcga
tgcaccatagaggagagagagaggagcgtgtgtttgcacatcttcctgcagatcgcggag
gcagtagaatttctgcacagtaaagggctcatgcacagggacctcaagccttccaacata
ttctttacaatggacgacgtggtcaagatcggagactttgggttagtgactgcaatggac
caggacgaggaagagcagatggttctgaccccaatgccagcatacgccagacacacagga
caagtggggaccaaactgtatatgagcccagagcagattcatggaaacaactactctcac
aaagtggacatcttttctttaggcctcatcctatttgaattgctatacccatttggcact
cagatggagagagtcaggatcttaaccgatgtaagaaatctcaaatttccaccactattt
actcagaaatatcctcgtgagcacgtgatggttcaagacatgctgtctccatcccccatg
gaacggcctgaagctacaaacatcattgaaaatgctgtgtttgaggacttggagtttcca
gggaaaacagtgctcagacagaggtctcgctccgtgagctcatcaggaacaaaaccttcc
agacagcccagcaactcccagagccctttgccgagcagttag
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