Equus caballus (horse): 100069340
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Entry
100069340 CDS
T01058
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04120
Ubiquitin mediated proteolysis
ecb04144
Endocytosis
ecb04330
Notch signaling pathway
ecb04668
TNF signaling pathway
ecb04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100069340 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100069340 (ITCH)
04668 TNF signaling pathway
100069340 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100069340 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100069340 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ecb04131
]
100069340 (ITCH)
04121 Ubiquitin system [BR:
ecb04121
]
100069340 (ITCH)
Enzymes [BR:
ecb01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100069340 (ITCH)
Membrane trafficking [BR:
ecb04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100069340 (ITCH)
Ubiquitin system [BR:
ecb04121
]
Ubiquitin ligases (E3)
HECT type E3
100069340 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100069340
NCBI-ProteinID:
XP_001916756
Ensembl:
ENSECAG00000016216
VGNC:
19157
UniProt:
A0A9L0RPW5
LinkDB
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Position
22:26203396..26313178
Genome browser
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
SSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTCSESASQNDDSSRPKDETRASTNGS
DDPEDVGSVENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPLTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLTMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccgagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaataca
agtagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacgctgaaatctgacgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccgacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacgtgttcagaaagtgct
tcacagaatgatgatagctccagacccaaggacgaaacaagagcaagcacaaatggatca
gatgaccctgaggacgtagggtctgttgaaaataggagggtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccatcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatctagcacaggctctctgccactaacgaatacaaattcaaatacatctgaaggagca
acgtctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtacctcaagctcccctaccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcag
ctccaacgtagtcaacttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaatact
cgtattacacaatgggaagatcccagaagtcaaggtcaactaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtggatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccctagacaatggaccccag
atagcctatgtacgagacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctgaccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaacccagcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctctgttccatgggaaattcattgacacaggtttttctttg
ccattctataagcgtatcttgaacaaaccagttggactaaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgttgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggcggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttttttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtccta
ttatgtggaatgcaagagattgatctgaatgactggcaaagacatgcaatctaccgtcat
tacactaggacaagcaagcaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccgattgcccgttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaactgaaggatttgga
caagagtaa
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