KEGG   Equus caballus (horse): 100073256
Entry
100073256         CDS       T01058                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00670  One carbon pool by folate
ecb00790  Folate biosynthesis
ecb01100  Metabolic pathways
ecb01240  Biosynthesis of cofactors
ecb01523  Antifolate resistance
ecb04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100073256 (DHFR)
   00670 One carbon pool by folate
    100073256 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100073256 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100073256 (DHFR)
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100073256 (DHFR)
SSDB
Motif
Pfam: DHFR_1 US2
Other DBs
NCBI-GeneID: 100073256
NCBI-ProteinID: XP_001504693
Ensembl: ENSECAG00000026827
UniProt: A0A9L0SH18
LinkDB
Position
14:85602747..85633122
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTASSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINLVLSRELKEPPQGAHFLAKSLDDALSLLEQPELANKVDMVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDTFFPEIDFEKYKLLPEYPGVLSDIQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaattgcatcgtcgccgtgtcgcagaatatgggcatcggcaagaac
ggggacctgccgtggcccccactcaggaatgaattcaagtatttccaaagaatgaccaca
gcctcttcagtagaaggtaagcagaatttggtgattatgggtaggaagacctggttctcc
atccctgagaagaatcggccgttaaaggacagaattaatttagttctcagtagagaactc
aaggaacctccacaaggagctcattttcttgccaaaagtttggatgatgccttatcactt
cttgagcaaccagaattagcaaataaagtggacatggtttggatagtgggaggcagttct
gtttataaggaagccatgaacaagccaggccatcttagactgtttgtgacaaggatcatg
caggaatttgaaagtgacacattttttccagaaattgattttgaaaaatataaacttctc
ccagaatacccaggtgttctttctgatatccaggaggaaaaaggcattaagtacaaattt
gaagtatatgaaaagaatgattaa

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