KEGG   Escherichia coli O6 K2 H1 CFT073 (UPEC): c0058
Entry
c0058             CDS       T00106                                 
Symbol
folA
Name
(GenBank) Dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecc  Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00670  One carbon pool by folate
ecc00790  Folate biosynthesis
ecc01100  Metabolic pathways
ecc01240  Biosynthesis of cofactors
ecc04981  Folate transport and metabolism
Module
ecc_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    c0058 (folA)
   00670 One carbon pool by folate
    c0058 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    c0058 (folA)
Enzymes [BR:ecc01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     c0058 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AAN78554
UniProt: P0ABQ5
LinkDB
Position
52319..52933
AA seq 204 aa
MRRVQGESVDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIG
MENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWV
KSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWES
VFSEFHDADAQNSHSYCFEILERR
NT seq 615 nt   +upstreamnt  +downstreamnt
atgcggcgagtccagggagagagcgtggactcgccagcagaatataaaattttcctcaac
atcatcctcgcaccagtcgacgacggtttacgctttacgtatagtggcgacaattttttt
tatcgggaaatctcaatgatcagtctgattgcggcgttagcggtagatcgcgttatcggc
atggaaaacgccatgccgtggaacctgcctgccgatctcgcctggtttaaacgcaacact
ttaaataaacccgtgattatgggccgccatacctgggaatccatcggtcgtccgttgcca
ggacgcaaaaatattatcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtg
aagtcggtggatgaagccattgcggcgtgtggtgacgtaccagaaatcatggtgattggc
ggcggtcgcgtttatgagcagttcctgccgaaagcgcaaaaactgtatctgacgcatatc
gacgcggaagtggaaggcgacacccatttcccggattacgagccggatgactgggaatcg
gtattcagcgaattccacgatgccgatgcgcagaactctcacagctattgctttgagatt
ctggagcggcggtaa

DBGET integrated database retrieval system