KEGG   Escherichia coli O157 H7 EDL933 (EHEC): Z0055
Entry
Z0055             CDS       T00044                                 
Name
(GenBank) dihydrofolate reductase type I; trimethoprim resistance
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ece  Escherichia coli O157:H7 EDL933 (EHEC)
Pathway
ece00670  One carbon pool by folate
ece00790  Folate biosynthesis
ece01100  Metabolic pathways
ece01240  Biosynthesis of cofactors
ece04981  Folate transport and metabolism
Module
ece_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ece00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    Z0055
   00670 One carbon pool by folate
    Z0055
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Z0055
Enzymes [BR:ece01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     Z0055
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AAG54351
UniProt: A0A6M0JFK5
LinkDB
Position
54238..54717
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTRESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgta
attatgggccgccataccagggaatccatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gagcagttcctgccgaaagcgcaaaaactgtacctgacgcatatcgacgcagaagtggaa
ggcgacacccattttccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgacgctgatgcgcagaactctcacagctattgttttgagattctggagcggcggtaa

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