Escherichia coli O157 H7 EDL933 (EHEC): Z5351
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Entry
Z5351 CDS
T00044
Symbol
metE
Name
(GenBank) tetrahydropteroyltriglutamate methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
ece
Escherichia coli O157:H7 EDL933 (EHEC)
Pathway
ece00270
Cysteine and methionine metabolism
ece00450
Selenocompound metabolism
ece01100
Metabolic pathways
ece01110
Biosynthesis of secondary metabolites
ece01230
Biosynthesis of amino acids
Module
ece_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ece00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
Z5351 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
Z5351 (metE)
Enzymes [BR:
ece01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
Z5351 (metE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
AAG59025
UniProt:
Q8X8L5
LinkDB
All DBs
Position
4878126..4880387
Genome browser
AA seq
753 aa
AA seq
DB search
MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLP
VGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFN
TNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPITWLWLGKVKGEQFDR
LSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLL
TTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLINGRNVWRAD
LTEKYVQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLC
DALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRAR
FKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVL
VHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYA
QSMTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDE
PALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDAD
VITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERL
WVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atgacaatattgaatcacaccctcggtttccctcgcgttggcctgcgtcgcgagctgaaa
aaagcgcaagagagttattgggcggggaactccacgcgtgaagaactgctggcggtaggg
cgtgaattgcgtgctcgtcactgggatcaacaaaagcaagcgggtatcgacctgctgccg
gtgggcgattttgcctggtacgatcatgtactgaccaccagtctgctgctgggtaacgtt
ccggcgcgtcatcagaacaaagatggttcggtagatatcgacaccctgttccgtattggt
cgtggacgtgcgccgactggcgaacctgcggcggcagcggaaatgaccaaatggtttaac
accaactatcactacatggtgccggagttcgttaaaggccaacagttcaaactgacctgg
acgcagctgctggacgaagtggacgaggcgctggcgctgggccacaaggtgaaacctgtg
ctgctggggccgattacctggctgtggctggggaaagtgaaaggtgaacagtttgaccgc
ctgagcctgctgaacgacattctgccggtttatcagcaagtgctggcagaactggcgaaa
cgtggcatcgagtgggtacagattgatgaacccgcgctggtactggaactaccacaggcg
tggctggacgcatacaaacccgcttacgacgcgctccagggacaggtgaaactgctgctg
accacctattttgaaggcgtaacgccaaatctcgacacgattactgcgctgcctgttcag
gggctgcatgtggaccttgtacatggtaaagatgacgttgttgaactgcacaagcgcctg
ccttctgactggctgctgtctgcgggtctgatcaatggtcgtaacgtctggcgcgccgat
cttactgagaaatatgtgcaaattaaggacattgtcggcaaacgtgatttgtgggtggca
tcttcctgctcgttgctgcacagccccatcgacctgagcgtggaaacgcgtcttgatgca
gaagtgaaaagctggtttgccttcgccctacaaaaatgccatgaactggcactgctgtgc
gatgcgctgaacagtggtgacacggcagctctggcagagtggagcgccccaattcaggcg
cgtcgtcactctactcgtgtacataatccggcggtagaaaagcgtctggcggcgatcacc
gcccaggacagccagcgtgcgaatgtytatgaagtgcgtgctgaagcccagcgtgcgcgt
tttaaactgccagcgtggccgaccaccacgattggttccttcccgcaaaccacggaaatt
cgtaccctgcgtctggatttcaaaaagggcaatctcgacgccaataactaccgcacgggc
attgcggaacatatcaggcaggccattgttgaacaggaacgtttgggactggatgtgctg
gtacatggcgaggccgagcgtaatgacatggtggaatactttggcgagcacctcgacggg
tttgtctttacgcaaaacggttgggtacagagctacggttcccgctgcgtgaagccaccg
attgttattggtgacgttagtcgcccggcaccgattaccgtggagtgggcgaagtatgcg
caatctatgactgataaaccggtgaaagggatgctgactggcccggtgaccattctctgc
tggtcgttcccgcgtgaagatgtcagccgtgaaaccatcgccaaacaaattgcgctggcg
ctgcgtgatgaagtggcggacctggaagccgcaggaattggcatcatccagattgatgaa
ccggcgctgcgcgaaggtttaccgctgcgtcgtagcgactgggatgcatatctccagtgg
ggcgtggaggccttccgtatcaacgccgccgtggcgaaagatgacacacaaatccacact
cacatgtgttattgcgagttcaacgacatcatggattcgattgcggcactggacgcagac
gtcatcaccatcgaaacctcgcgttctgacatggagttgctggagtcgttcgaagagttt
gattatccgaatgaaatcggtccaggcgtctatgacattcactcgccaaacgtaccgagc
gtggaatggattgaagccttgctgaagaaagcggcaaaacgcattccggcagagcgcctg
tgggtcaacccggactgtggcctgaaaacgcgcggctggccagaaacccgcgcggcactg
gcgaacatggtgcaggcggcgcagaacttgcgtcgggggtaa
Escherichia coli O157 H7 EDL933 (EHEC): Z5610
Help
Entry
Z5610 CDS
T00044
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ece
Escherichia coli O157:H7 EDL933 (EHEC)
Pathway
ece00270
Cysteine and methionine metabolism
ece00450
Selenocompound metabolism
ece00670
One carbon pool by folate
ece01100
Metabolic pathways
ece01110
Biosynthesis of secondary metabolites
ece01230
Biosynthesis of amino acids
ece04980
Cobalamin transport and metabolism
ece04981
Folate transport and metabolism
Module
ece_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ece00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
Z5610 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
Z5610 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
Z5610 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
Z5610 (metH)
04980 Cobalamin transport and metabolism
Z5610 (metH)
Enzymes [BR:
ece01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
Z5610 (metH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AAG59211
UniProt:
A0A9Q6ZME1
LinkDB
All DBs
Position
5100974..5104657
Genome browser
AA seq
1227 aa
AA seq
DB search
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAQ
AGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVN
KRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYP
ACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDYARRKGMSVSDVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagtggaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcaccatgatccagagctatcgactgaacgaagccgattttcgtggtgaa
cgctttgccgactggccatgcgacctcaaaggcaataacgatctgctggtgctaagcaaa
ccggaagtgatcgccgctatccacaacgcctactttgaagcgggcgcggatatcatcgaa
accaacaccttcaactccacgaccattgcgatggcggattaccagatggaatccctgtcg
gcggaaatcaactttgcggcggcgaaactggcgcgcgcctgtgctgacgagtggaccgcg
cgcacgccggagaaaccgcgctacgttgccggcgttctcggcccaaccaaccgcacggcg
tccatttctccggacgtgaacgatccggcattccgcaacatcacttttgaccagctggtg
gcggcctatcgcgaatccaccaaagcattagtggaaggcggtgcggatctgattctgatt
gaaaccgttttcgacacccttaacgccaaagcggcggtctttgcggtgaaaacggagttc
gaagcgttaggcgttgagctgccgattatgatctccggcaccatcaccgacgcctccggg
cgcacgctctccggacagaccaccgaagcattttacaactccctgcgccatgccgaagcc
ctgacttttggcctcaactgcgcgctggggccagatgaactgcgccagtacgtgcaggaa
ctatcacggattgcggaatgctacgtcaccgcgcacccgaacgccgggctacccaacgcc
tttggtgagtacgatctcgacgccgacacgatggcaaaacagatacgtgaatgggcgcaa
gcgggttttctcaatatcgtcggcggctgctgtggcaccacgccacaacatattgcagcg
atgagtcgtgcagtagaaggattagcgccgcgcaaactgcctgaaattcccgtagcctgc
cgtttgtccggcctggagccgctgaacattggcgacgatagcctgtttgtgaacgtgggt
gaacgcaccaacgtcaccggttccgctaagttcaagcgcctgatcaaagaagagaaatac
agcgaggcgctggatgtagcgcgtcagcaggtggaaaacggcgcgcagattatcgatatc
aacatggatgaagggatgctcgatgccgaagcggcgatggtgcgttttctcaatctgatt
gccggtgaaccggatatcgctcgcgtgccgattatgatcgactcctcaaaatgggaggtc
atcgaaaaggggctgaagtgtattcagggcaaaggcattgttaactctatctcaatgaaa
gagggcgtcgacgcctttatccatcatgcgaaactgttgcgtcgttacggtgcagcggtg
gtggtaatggcctttgacgaacaggggcaggccgatacccgcgcacggaaaattgagatt
tgccgtcgggcgtacaaaatcctcaccgaagaggttggcttcccgccagaagatatcatc
ttcgacccgaacatcttcgcggtcgccaccggcattgaagagcacaacaactatgcgcag
gactttatcggcgcctgcgaagacatcaaacgcgaactgccgcacgcgctgatttccggc
ggcgtatctaacgtttctttctcattccgtggcaacgatccggtgcgcgaagccattcac
gcggtgttcctctactacgctattcgcaatggcatggatatggggatcgtcaacgccggg
caactggcgatttacgacgacctgcccgctgaactgcgcgacgcggtggaagatgtgatt
cttaatcgtcgcgatgatggcactgagcgtttactggagcttgccgagaaatatcgcggc
agcaaaaccgacgacaccgctaacgcccagcaggcggagtggcgctcgtgggaagtgaat
aaacgtctggaatactcgctggtcaaaggcattactgagtttatcgagcaggataccgaa
gaagcccgccagcaggctacgcgcccgattgaagtgattgaaggcccgctaatggacggc
atgaacgtggtcggcgatctgttcggcgaagggaaaatgttcctgccacaggtggtcaaa
tcggcgcgtgtgatgaagcaggcagtggcctacctcgaaccgtttattgaagccagcaaa
gagcagggcaaaaccaacggcaagatggtgatcgccaccgtgaagggcgacgtccacgac
atcggtaaaaatatcgttggtgtggtgctgcaatgtaacaactacgaaattgtcgatctc
ggcgttatggtgcctgcggaaaaaattctccgtaccgctaaagaagtgaatgctgatctg
attggactttcggggcttatcacgccgtcgctggacgagatggttaacgtggcgaaagag
atggagcgtcagggcttcaccattccgttactgatcggtggcgcgacgacctcaaaagcg
cacacggcggtgaaaatcgagcagaactacagcggcccgacggtgtatgtgcagaatgcc
tcgcgcaccgttggtgtggtggcggcgctgctttccgatactcagcgcgatgattttgtc
gctcgtacccgcaaggagtacgaaaccgtacgtattcagcacgggcgcaagaaaccacgc
acaccaccggtcacgctggaagcggcgcgcgataacgacttcgcttttgactggcaggct
tacacgccgccggtggcgcaccgtctcggcgtgcaggaagttgaagccagcatcgaaact
ctgcgtaattacatcgactggacaccgttctttatgacctggtcgctggccgggaagtat
ccgcgcattctggaagatgaagtggtgggcgttgaggcgcagcggctgtttaaagacgcc
aacgacatgctggataaattaagcgccgagaaaacgctgaatccgcgtggcgtggtgggc
ctgttcccggcaaaccgtgtgggcgatgacattgaaatctaccgtgacgaaacgcgcacc
catgtgatcaacgtcagccaccatctgcgtcaacagaccgaaaaaacgggattcgctaac
tactgtctcgctgacttcgttgcgccgaagctttctggtaaagcagattacatcggcgca
tttgccgtgactggcgggctggaagaggacgcactggctgatgcctttgaagcgcagcac
gatgattacaacaaaatcatggtgaaagcgcttgccgaccgtttagccgaagcctttgcg
gagtatctccatgagcgtgtgcgtaaagtctactggggctatgcgccgaacgagaacctc
agcaacgaagaactgatccgcgaaaactaccagggcatccgtccggcaccgggctacccg
gcctgcccggaacatacggaaaaagccaccatctgggagctgctggaagtggaaaaacat
accggcatgaaactcacagaatctttcgccatgtggcccggtgcatcggtttcgggttgg
tatttcagccacccggacagcaagtactacgcggtggcgcaaattcagcgcgatcaggtt
gaagactatgcccgccgtaaaggtatgagcgtctccgatgttgagcgctggctggcaccg
aatctggggtatgacgcggactga
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