KEGG   Escherichia coli O157 H7 EC4115 (EHEC): ECH74115_0052
Entry
ECH74115_0052     CDS       T00778                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecf  Escherichia coli O157:H7 EC4115 (EHEC)
Pathway
ecf00670  One carbon pool by folate
ecf00790  Folate biosynthesis
ecf01100  Metabolic pathways
ecf01240  Biosynthesis of cofactors
ecf04981  Folate transport and metabolism
Module
ecf_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecf00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    ECH74115_0052 (folA)
   00670 One carbon pool by folate
    ECH74115_0052 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ECH74115_0052 (folA)
Enzymes [BR:ecf01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     ECH74115_0052 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ACI34657
LinkDB
Position
54122..54712
AA seq 196 aa
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWN
LPADLAWFKRNTLNKPVIMGRHTRESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIA
ACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDA
DAQNSHSYCFEILERR
NT seq 591 nt   +upstreamnt  +downstreamnt
gtggactcgccagcagaatataaaattttcctcaacatcatcctcgcaccagtcgacgac
ggtttacgctttacgtatagtggcgacaattttttttatcgggaaatctcaatgatcagt
ctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatgccgtggaac
ctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtaattatgggc
cgccataccagggaatccatcggtcgtccgttgccaggacgcaaaaatattatcctcagc
agtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaagccatcgcg
gcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttatgagcagttc
ctgccgaaagcgcaaaaactgtacctgacgcatatcgacgcagaagtggaaggcgacacc
cattttccggattacgagccggatgactgggaatcggtattcagcgaattccacgacgct
gatgcgcagaactctcacagctattgttttgagattctggagcggcggtaa

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