KEGG   Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_0049
Entry
E2348C_0049       CDS       T00796                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecg  Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00670  One carbon pool by folate
ecg00790  Folate biosynthesis
ecg01100  Metabolic pathways
ecg01240  Biosynthesis of cofactors
ecg04981  Folate transport and metabolism
Module
ecg_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecg00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    E2348C_0049 (folA)
   00670 One carbon pool by folate
    E2348C_0049 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    E2348C_0049 (folA)
Enzymes [BR:ecg01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     E2348C_0049 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: CAS07597
UniProt: B7UI94
LinkDB
Position
52699..53178
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacactttaaataaacccgtg
attatgggccgccatacctgggaatccatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccattgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gagcagttcctgccgaaagcgcaaaaactgtatctgacgcatatcgacgcggaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgacgctgatgcgcagaactctcatagctattgctttgagattctggagcggcggtaa

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