KEGG   Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_0397
Entry
E2348C_0397       CDS       T00796                                 
Symbol
acrB
Name
(GenBank) multidrug efflux system protein
  KO
K18138  multidrug efflux pump
Organism
ecg  Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg01501  beta-Lactam resistance
ecg01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:ecg00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    E2348C_0397 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    E2348C_0397 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ecg02000]
    E2348C_0397 (acrB)
   01504 Antimicrobial resistance genes [BR:ecg01504]
    E2348C_0397 (acrB)
Transporters [BR:ecg02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   E2348C_0397 (acrB)
Antimicrobial resistance genes [BR:ecg01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    E2348C_0397 (acrB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF_C
Other DBs
NCBI-ProteinID: CAS07945
UniProt: B7UKE2
LinkDB
Position
complement(441731..444880)
AA seq 1049 aa
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT
VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ
EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS
QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL
TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL
DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ
NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR
YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTNYYLT
KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD
AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG
LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR
MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA
MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS
VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL
IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF
FVPVFFVVVRRRFSRKNEDIEHSHTVDHH
NT seq 3150 nt   +upstreamnt  +downstreamnt
atgcctaatttctttatcgatcgcccgatttttgcgtgggtgatcgccattatcatcatg
ttggcaggggggctggcgatcctcaaactgccggtggcgcaatatcctacgattgcaccg
ccggcagtaacgatctccgcctcctaccctggcgctgatgcgaaaacagtgcaggacacg
gtgacacaggttatcgaacagaatatgaacggtatcgataacctgatgtacatgtcctct
aacagtgactccacgggtaccgtgcagatcaccctgacctttgagtctggtactgatgcg
gatatcgcgcaggttcaggtacagaacaaactgcagttggcgatgccgttgctgccacaa
gaagtacagcagcaaggggtgagcgttgagaaatcatccagcagcttcctgatggttgtc
ggcgttatcaacaccgatggcaccatgacgcaggaggatatctccgactacgtggcggcg
aatatgaaagatgccatcagccgtacgtcgggcgtgggtgacgttcagttgttcggttca
cagtacgcgatgcgtatctggatgaacccgaatgaactgaacaaattccagctaacgccg
gttgatgtcattaccgccatcaaagcacagaacgcccaggttgcagctggtcagctcggt
ggtacgccgccggtgaaaggccaacagcttaacgcctctattattgctcagacgcgtctg
acctctactgaagagttcggcaaaatcctgctgaaagtgaatcaggatggttcccgtgtg
ctgctgcgtgatgtggcgaaaattgagctgggtggagagaactacgacatcatcgcagag
tttaacggccaaccggcttccggtctggggatcaagctggcgaccggtgcgaacgcgctg
gataccgctgcggcaatccgtgctgaactggcgaagatggaaccgttcttcccgtcaggt
ctgaaaattgtttacccgtatgacaccacaccgttcgtgaaaatctctattcacgaagtg
gttaaaacactggtcgaagcgatcatcctcgtgttcctggtaatgtatctgttcttgcag
aacttccgcgcgacgttgattccgaccattgccgtaccggtggtattgctcgggaccttt
gccgtccttgccgcctttggcttctcgataaacacgctaacaatgttcgggatggtgctc
gccatcggcctgttggtggatgacgctatcgttgtggtagaaaacgttgagcgtgtgatg
gcggaagaaggtttgccgccaaaagaagccacccgtaagtcgatggggcagattcagggc
gctctggtcggtatcgcgatggtactgtcggcggtattcgtaccgatggccttctttggc
ggttctactggtgctatctatcgtcagttctctattaccattgtttcagcaatggcgctg
tcggtactggtggcgttgatcctgactccggctctttgtgccaccatgctgaaaccgatt
gccaaaggcgatcacggggaaggtaaaaaaggcttcttcggctggtttaaccgtatgttc
gagaagagcacgcaccactacaccgacagcgtaggcggtattctgcgcagtacggggcgt
tacctggtgctgtatctgatcatcgtggtcggtatggcctatctgttcgtgcgtctgcca
agctccttcttgccagatgaggaccagggcgtatttatgaccatggttcagctgccagca
ggtgcaacgcaggaacgtacgcagaaagtgctcaatgaggtaacgaattactatctgacc
aaagaaaagaacaacgttgagtcggtgttcgccgttaacggcttcggctttgcgggacgt
ggtcagaataccggtattgcgttcgtttccttgaaggattgggccgatcgtccgggcgaa
gaaaacaaagttgaagcgattaccatgcgtgcaacacgtgctttctcgcaaatcaaagat
gcgatggttttcgcctttaacctgcccgcaatcgtggaactgggtaccgcaaccggcttt
gactttgagctaattgaccaggctggccttggtcacgaaaaactgactcaggcgcgtaac
cagttgcttgcagaagcagcgaagcaccctgatatgttgaccagcgtacgtccaaacggt
ctggaagataccccgcagtttaagattgatatcgaccaggaaaaagcgcaggcgctgggt
gtttctatcaacgacattaacaccactctgggcgctgcatggggcggtagctatgtgaac
gactttatcgaccgcggtcgtgtgaagaaagtttacgtcatgtcagaagcgaaataccgt
atgctgccggatgatatcggcgactggtatgttcgtgctgctgatggtcagatggtgccg
ttctcggcgttctcctcttctcgttgggagtacggttcgccgcgtctggaacgttacaac
ggcctgccatccatggaaatcttaggccaggcggcaccgggtaaaagtaccggtgaagca
atggagctgatggaacaactggcgagcaaactgcctaccggtgttggctatgactggacg
gggatgtcctatcaggaacgtctctccggcaaccaggcaccttcactgtacgcgatttcg
ttgattgtcgtgttcctgtgtctggcggcgctgtacgagagctggtcgattccgttctcc
gttatgctggtcgttccgctgggggttatcggtgcgttgctggctgccaccttccgtggc
ctgaccaatgacgtttacttccaggtaggcctgctcacaaccattgggttgtcggcgaag
aacgcgatacttatcgtcgaattcgccaaagacttgatggataaagaaggtaaaggtctg
attgaagcgacgcttgatgcggtgcggatgcgtttacgtccgatcctgatgacctcgctg
gcgtttatcctcggcgttatgccgctggttatcagtactggtgctggttccggcgcgcag
aacgcagtaggtaccggtgtaatgggcgggatggtgaccgcaacggtactggcaatcttc
ttcgttccggtattctttgtggtggttcgccgccgctttagccgcaagaatgaagatatc
gagcacagccatactgtcgatcatcattga

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