Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_2874
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Entry
E2348C_2874 CDS
T00796
Symbol
tyrA
Name
(GenBank) fused chorismate mutase T/prephenate dehydrogenase
KO
K14187
chorismate mutase / prephenate dehydrogenase [EC:
5.4.99.5
1.3.1.12
]
Organism
ecg
Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00400
Phenylalanine, tyrosine and tryptophan biosynthesis
ecg00401
Novobiocin biosynthesis
ecg01100
Metabolic pathways
ecg01110
Biosynthesis of secondary metabolites
ecg01230
Biosynthesis of amino acids
Module
ecg_M00024
Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
ecg_M00025
Tyrosine biosynthesis, chorismate => HPP => tyrosine
Brite
KEGG Orthology (KO) [BR:
ecg00001
]
09100 Metabolism
09105 Amino acid metabolism
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
E2348C_2874 (tyrA)
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
E2348C_2874 (tyrA)
Enzymes [BR:
ecg01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.12 prephenate dehydrogenase
E2348C_2874 (tyrA)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.5 chorismate mutase
E2348C_2874 (tyrA)
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Motif
Pfam:
CM_2
PDH_C
PDH_N
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
CAS10422
UniProt:
B7UH34
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Position
complement(2970962..2972083)
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AA seq
373 aa
AA seq
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MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAE
AEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVVIVGGGGQMGRLFEKMLTL
SGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNG
PLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRI
SAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDP
QLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSE
SRVLLRQANDNRQ
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggttgctgaattgaccgcattacgcgatcaaattgatgaagtcgataaagcgctgctg
aatttattagcgaagcgtctggaactggttgctgaagtgggcgaggtgaaaagccgcttt
ggactgcctatttatgttccggagcgcgaggcatctatgttggcctcgcgtcgtgcagag
gcggaagctctgggtgtaccgccagatctgattgaggatgttttgcgtcgggtgatgcgt
gaatcttactccagtgaaaacgacaaaggatttaaaacgctttgtccgtcactgcgcccg
gtggttatcgtcggtggtggcggtcagatggggcgtctgttcgagaagatgctgacactc
tcgggttatcaggtgcggattctggagcaacatgactgggatcgagcggctgatattgtt
gccgatgccggaatggtgattgttagtgtgcccatccacgttactgagcaagttatcggc
aaattaccgcctttaccgaaagattgtattctggttgatctggcatcggtgaaaaatggg
ccattacaggccatgctggcggcgcacgatggcccggtgctggggttacacccgatgttc
ggcccggacagcggtagcctggcaaagcaagttgtggtctggtgtgatggacgtaagccg
gaagcataccaatggtttctggagcaaattcaggtctggggcgctcggttgcatcgtatt
agcgctgtcgagcacgatcagaatatggcgtttattcaggctttgcgccactttgctact
tttgcttatgggctgcacctggcagaagaaaatgttcagcttgagcaactactggcgctc
tcttcgccgatttaccgccttgagctggcgatggtcgggcgactgtttgctcaggatccg
cagctttatgccgacattattatgtcgtcagagcgtaatctggcgttaatcaaacgttac
tataagcgtttcggcgaggcgattgagttgctggagcagggcgataagcaggcgtttatt
gacagtttccgcaaggtggagcactggttcggtgattacgcacagcgttttcagagtgaa
agccgcgtgttattgcgtcaggcgaatgacaatcgccagtaa
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