KEGG   Escherichia coli K-12 W3110: JW0047
Entry
JW0047            CDS       T00068                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecj  Escherichia coli K-12 W3110
Pathway
ecj00670  One carbon pool by folate
ecj00790  Folate biosynthesis
ecj01100  Metabolic pathways
ecj01240  Biosynthesis of cofactors
ecj04981  Folate transport and metabolism
Module
ecj_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecj00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    JW0047 (folA)
   00670 One carbon pool by folate
    JW0047 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    JW0047 (folA)
Enzymes [BR:ecj01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     JW0047 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: BAB96616
UniProt: P0ABQ4
Structure
LinkDB
Position
49823..50302
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg
attatgggccgccatacctgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gaacagttcttgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgatgctgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

DBGET integrated database retrieval system