Escherichia coli K-12 W3110: JW0377
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Entry
JW0377 CDS
T00068
Symbol
proC
Name
(GenBank) pyrroline-5-carboxylate reductase, NAD(P)-binding
KO
K00286
pyrroline-5-carboxylate reductase [EC:
1.5.1.2
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00330
Arginine and proline metabolism
ecj01100
Metabolic pathways
ecj01110
Biosynthesis of secondary metabolites
ecj01230
Biosynthesis of amino acids
Module
ecj_M00015
Proline biosynthesis, glutamate => proline
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09105 Amino acid metabolism
00330 Arginine and proline metabolism
JW0377 (proC)
Enzymes [BR:
ecj01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.2 pyrroline-5-carboxylate reductase
JW0377 (proC)
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Gene cluster
GFIT
Motif
Pfam:
P5CR_dimer
F420_oxidored
NAD_binding_2
Sacchrp_dh_NADP
Shikimate_DH
GFO_IDH_MocA
OCD_Mu_crystall
2-Hacid_dh_C
FAD_binding_4
PDH_N
RS_preATP-grasp-like
Motif
Other DBs
NCBI-ProteinID:
BAE76167
UniProt:
P0A9L8
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Position
complement(404059..404868)
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AA seq
269 aa
AA seq
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MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEV
AQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMP
NTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVF
MFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAV
RVLEEKGFRAAVIEAMTKCMEKSEKLSKS
NT seq
810 nt
NT seq
+upstream
nt +downstream
nt
atggaaaagaaaatcggttttattggctgcggcaatatgggaaaagccattctcggcggt
ctgattgccagcggtcaggtgcttccagggcaaatctgggtatacaccccctccccggat
aaagtcgccgccctgcatgaccagttcggcatcaacgccgcagaatcggcgcaagaagtg
gcgcaaatcgccgacatcatttttgctgccgttaaacctggcatcatgattaaagtgctt
agcgaaatcacctccagcctgaataaagactctctggtcgtttctattgctgcaggtgtc
acgctcgaccagcttgcccgcgcgctgggccatgaccggaaaattatccgcgccatgccg
aacactcccgcactggttaatgccgggatgacctccgtaacgccaaacgcgctggtaacc
ccagaagataccgctgatgtgctgaatattttccgctgctttggcgaagcggaagtaatt
gctgagccgatgatccacccggtggtcggtgtgagcggttcttcgccagcctacgtattt
atgtttatcgaagcgatggccgacgccgccgtgctgggcgggatgccacgcgcccaggcg
tataaatttgccgctcaggcggtaatgggttccgcaaaaatggtgctggaaacgggagaa
catccgggggcactgaaagatatggtctgctcaccgggaggcaccaccattgaagcggta
cgcgtactggaagagaaaggcttccgtgctgcagtgatcgaagcgatgacgaagtgtatg
gaaaaatcagaaaaactcagcaaatcctga
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