| Entry |
|
| Symbol |
proC
|
| Name |
pyrroline-5-carboxylate reductase [EC: 1.5.1.2]
|
| Pathway |
| map00330 | Arginine and proline metabolism |
| map01110 | Biosynthesis of secondary metabolites |
|
| Module |
| M00015 | Proline biosynthesis, glutamate => proline |
|
| Reaction |
| R01248 | L-proline:NAD+ 5-oxidoreductase |
| R01251 | L-proline:NADP+ 5-oxidoreductase |
| R03291 | trans-4-hydroxy-L-proline:NAD+ 5-oxidoreductase |
| R03293 | trans-4-hydroxy-L-proline:NADP+ 5-oxidoreductase |
|
| Disease |
| H00558 | Geroderma osteodysplasticum |
| H00679 | Hypomyelinating leukodystrophy |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09105 Amino acid metabolism
00330 Arginine and proline metabolism
K00286 proC; pyrroline-5-carboxylate reductase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.2 pyrroline-5-carboxylate reductase
K00286 proC; pyrroline-5-carboxylate reductase
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Deutch AH, Smith CJ, Rushlow KE, Kretschmer PJ |
| Title |
Escherichia coli delta 1-pyrroline-5-carboxylate reductase: gene sequence, protein overproduction and purification. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Dougherty KM, Brandriss MC, Valle D |
| Title |
Cloning human pyrroline-5-carboxylate reductase cDNA by complementation in Saccharomyces cerevisiae. |
| Journal |
J Biol Chem 267:871-5 (1992) |
| Sequence |
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| LinkDB |
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