Escherichia coli K-12 W3110: JW2008
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Entry
JW2008 CDS
T00068
Symbol
hisI
Name
(GenBank) fused phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase
KO
K11755
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:
3.5.4.19
3.6.1.31
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00340
Histidine metabolism
ecj01100
Metabolic pathways
ecj01110
Biosynthesis of secondary metabolites
ecj01230
Biosynthesis of amino acids
Module
ecj_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
JW2008 (hisI)
Enzymes [BR:
ecj01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
JW2008 (hisI)
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
JW2008 (hisI)
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Gene cluster
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Motif
Pfam:
PRA-CH
PRA-PH
MazG
Motif
Other DBs
NCBI-ProteinID:
BAA15858
UniProt:
P06989
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All DBs
Position
2098751..2099362
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AA seq
203 aa
AA seq
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MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTLESGKVTFFSRTKQR
LWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQ
LLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHL
LVLLQDQGLDLTTVIENLRKRHQ
NT seq
612 nt
NT seq
+upstream
nt +downstream
nt
atgttaacagaacaacaacgtcgcgaactggactgggaaaaaaccgacggacttatgccg
gtgattgtgcaacacgcggtatccggcgaagtgctaatgctgggctatatgaacccggaa
gccttagacaaaaccctcgaaagcggcaaagtcaccttcttctcgcgcactaaacagcga
ctgtggaccaaaggcgaaacgtcgggcaatttcctcaacgtagtgagtattgccccggac
tgcgacaacgacacgttactggtgctggcgaatcccatcggcccgacctgccacaaaggc
accagcagttgcttcggcgacaccgctcaccagtggctgttcctgtatcaactggaacaa
ctgctcgccgagcgcaaatctgccgatccggaaacctcctacaccgccaaactgtatgcc
agcggcaccaaacgcattgcgcagaaagtgggtgaagaaggcgtggaaaccgcgctggca
gcaacggtacatgaccgctttgagctgaccaacgaggcgtctgatttgatgtatcacctg
ctggtgttgttgcaggatcaggggctggatttaacgacggtaattgagaacctgcgtaaa
cggcatcagtga
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