Escherichia coli K-12 W3110: JW2975
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Entry
JW2975 CDS
T00068
Symbol
metC
Name
(GenBank) cystathionine beta-lyase, PLP-dependent
KO
K01760
cysteine-S-conjugate beta-lyase [EC:
4.4.1.13
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00270
Cysteine and methionine metabolism
ecj00450
Selenocompound metabolism
ecj01100
Metabolic pathways
ecj01110
Biosynthesis of secondary metabolites
ecj01230
Biosynthesis of amino acids
Module
ecj_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
JW2975 (metC)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
JW2975 (metC)
Enzymes [BR:
ecj01000
]
4. Lyases
4.4 Carbon-sulfur lyases
4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
4.4.1.13 cysteine-S-conjugate beta-lyase
JW2975 (metC)
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Motif
Pfam:
Cys_Met_Meta_PP
Aminotran_5
Motif
Other DBs
NCBI-ProteinID:
BAE77065
UniProt:
P06721
Structure
PDB
PDBj
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Position
3150892..3152079
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AA seq
395 aa
AA seq
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MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRG
TLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYEPSQDFCSK
ILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVAAVRSVVPDA
IIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLM
GQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFW
KRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRP
QGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARIV
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atggcggacaaaaagcttgatactcaactggtgaatgcaggacgcagcaaaaaatacact
ctcggcgcggtaaatagcgtgattcagcgcgcttcttcgctggtctttgacagtgtagaa
gccaaaaaacacgcgacacgtaatcgcgccaatggagagttgttctatggacggcgcgga
acgttaacccatttctccttacaacaagcgatgtgtgaactggaaggtggcgcaggctgc
gtgctatttccctgcggggcggcagcggttgctaattccattcttgcttttatcgaacag
ggcgatcatgtgttgatgaccaacaccgcctatgaaccgagtcaggatttctgtagcaaa
atcctcagcaaactgggcgtaacgacatcatggtttgatccgctgattggtgccgatatc
gttaagcatctgcagccaaacactaaaatcgtgtttctggaatcgccaggctccatcacc
atggaagtccacgacgttccggcgattgttgccgccgtacgcagtgtggtgccggatgcc
atcattatgatcgacaacacctgggcagccggtgtgctgtttaaggcgctggattttggc
atcgatgtttctattcaagccgccaccaaatatctggttgggcattcagatgcgatgatt
ggcactgccgtgtgcaatgcccgttgctgggagcagctacgggaaaatgcctatctgatg
ggccagatggtcgatgccgataccgcctatataaccagccgtggcctgcgcacattaggt
gtgcgtttgcgtcaacatcatgaaagcagtctgaaagtggctgaatggctggcagaacat
ccgcaagttgcgcgagttaaccaccctgctctgcctggcagtaaaggtcacgaattctgg
aaacgagactttacaggcagcagcgggctattttcctttgtgcttaagaaaaaactcaat
aatgaagagctggcgaactatctggataacttcagtttattcagcatggcctactcgtgg
ggcgggtatgaatcgttgatcctggcaaatcaaccagaacatatcgccgccattcgccca
caaggcgagatcgattttagcgggaccttgattcgcctgcatattggtctggaagatgtc
gacgatctgattgccgatctggacgccggttttgcgcgaattgtataa
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