Enterobacter roggenkampii 35734: LI67_002125
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Entry
LI67_002125 CDS
T04878
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ecls
Enterobacter roggenkampii 35734
Pathway
ecls00270
Cysteine and methionine metabolism
ecls00450
Selenocompound metabolism
ecls00670
One carbon pool by folate
ecls01100
Metabolic pathways
ecls01110
Biosynthesis of secondary metabolites
ecls01230
Biosynthesis of amino acids
ecls04981
Folate transport and metabolism
Module
ecls_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ecls00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LI67_002125 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
LI67_002125 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
LI67_002125 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
LI67_002125 (metH)
04980 Cobalamin transport and metabolism
LI67_002125 (metH)
Enzymes [BR:
ecls01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
LI67_002125 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AKZ71554
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All DBs
Position
1:265176..268859
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AA seq
1227 aa
AA seq
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MSSKVEQLRAQLNERILVLDGGMGTMIQGYRLSEDDFRGERFADWPCDLKGNNDLLVLSK
PSVIKDIHNAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFEAAKLARACADEWTA
RTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVVAYRESTRALVEGGSDLILI
ETVFDTLNAKAAIYAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHADA
LSFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSNAVAGLPPRKLPELPVACRLSGLEPLTIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDTFIHHAKQVRRYGAAV
VVMAFDEVGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDATERLLDLAEKYRGSKSDDAANVQQAEWHAWDVK
KRLEYSLVKGITEFIEQDTEEARQQSARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILKTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQRDEFVERTRKEYETVRIQHGRKKPR
TPPVSLQAARDNDLAFDWSSYTPPVAHRLGVQEVSASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFNDANDMLDRLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLAVSRHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQY
DDYNKIMVKAIADRLAEAFAEYLHERVRKVHWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEAHTGMKLTESYAMWPGASVSGWYFSHPDSKYFAVAQLQRDQI
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagtagagcaactgcgtgcgcagttaaatgaacgaattctggtgctggac
ggcggcatgggcaccatgatccagggttatcgcctgagcgaagacgatttccgcggcgaa
cgcttcgccgactggccctgcgacctgaaagggaacaacgacctgctggtgctcagcaag
ccgtccgtgatcaaggatattcacaacgcctacttcgaagcgggtgcggatatcgttgaa
accaacacctttaactcgacaaccatcgccatggcggattaccagatggaatccctgtcg
gcggagatcaactttgaagccgcaaagcttgcgcgcgcctgcgccgacgagtggacggcc
cgcacgccggacaagccgcgctatgttgccggggtgcttggcccaaccaaccgcaccgcg
tcgatttcaccggacgtcaacgacccggcgtttcgtaatatcacctttgaccagctggtt
gttgcctaccgtgaatcgaccagagcgctggtggaaggcggttccgatctgatcctgatt
gaaacggtattcgacaccctcaacgccaaggccgcgatttacgcggtgaaagaggagttc
gaggcgctgggcgttgacctgccgatcatgatttccggcaccatcaccgatgcctccggc
cgtaccctgtccggccagaccaccgaagcgttttataactccctgcgccacgccgacgcg
ctctccttcggcctgaactgcgcgctgggcccggacgagctgcgccagtacgtgcaggag
ctgtcgcgcattgcggaatgctacgttaccgcgcacccgaacgccggtctgccgaacgcc
ttcggtgaatacgatctggatgccgacaccatggcggcacaaatccgcgagtgggccgag
tctggatttctcaacatcgtcggcggctgctgcggcaccacgccggagcacatcgccgca
atgagcaacgccgtggccggactgccgccgcgcaagctgcccgagctgccggttgcctgt
cgcctctcgggccttgagccgttaaccatcggcgacgacagcctgtttgtgaacgtgggt
gagcgtacaaacgtcaccggctccgcgaagttcaagcgtctgatcaaagaagagaagtac
agcgaagcgctggacgttgcccgccagcaggtggaaagcggcgcgcagattatcgatatc
aacatggatgaggggatgctcgatgccgaggcggcgatggtgcgtttcctcaacctgatt
gccggtgagccggacatcgcccgcgtgccgatcatgatcgactcgtccaaatgggaggtg
atcgagaaggggctgaagtgcattcagggtaaaggcatcgtcaactccatctcgatgaaa
gagggcgttgatacctttattcatcacgctaagcaggtccgccgctacggtgccgccgtg
gtggtcatggcctttgatgaagtgggccaggccgacactcgcgcgcgtaaaattgagatt
tgccgccgcgcgtacaaaatactgaccgaagaggtaggcttcccgccggaagacatcatc
tttgacccgaacatcttcgccgtggcgaccggcatcgaagagcacaacaactacgcccag
gactttatcggcgcgtgcgaggacatcaagcgcgagctgccgcatgccctcatctccggc
ggcgtgtcgaacgtctcgttctcgttccgcggcaacgacccggtgcgtgaagcgattcac
gccgtgttcctctactacgccatccgcaacgggatggacatggggatcgtcaacgccggc
cagctggcgatttacgacgacctgcccgccgagctgcgcgacgcggtggaagacgtgatc
ctcaaccgccgcgacgacgccacggagcggctgcttgacctggcagaaaaataccgcggc
agcaagtcggatgacgcagccaacgttcagcaggccgagtggcacgcctgggacgtgaaa
aaacgtctggaatattcgctggtaaaaggcatcaccgagtttatcgagcaggacaccgaa
gaggcgcgtcagcagtcagcccgcccgattgaagtgatcgaagggccgctgatggacggc
atgaacgtggtgggcgatctgttcggcgagggcaaaatgttcctgccgcaggtggtgaaa
tccgcgcgcgtgatgaagcaggccgtggcgtacctggagccgtttatcgaagccagcaaa
gagaaaggctccagcaacggcaaaatggtcatcgccaccgtgaagggcgacgtgcacgac
atcggcaagaacatcgtcggcgtggtgctgcagtgcaataactacgagattatcgacctt
ggcgtgatggtcccggcggataaaatcctcaagaccgcgcgcgaagtgaatgccgacctg
attggcctctccgggctgatcaccccgtcgctggacgagatggttaacgtggcgaaggag
atggagcgtcagggcttcaccattccgctgctgattggcggcgcgaccacctccaaggcg
cacacggcggtgaaaatcgagcagaactacagcgggccgacggtctacgtgcagaacgcc
tcgcgcacggtgggcgtggtctccgcgctgctctctgacacccagcgcgacgagtttgtt
gagcgcacccgcaaagaatacgaaaccgttcgcatccagcacgggcgcaagaaaccgcgc
accccgccagtttcactccaggcggcgcgcgataacgatctggcgtttgactggtcgagc
tatacgccgccggtcgcgcatcgcctgggcgttcaggaggtcagtgccagcatcgaaacg
ctgcgtaactacatcgactggacgccgttctttatgacctggtcgctcgcgggcaaatat
ccgcgcatcctggaagatgaggtggtgggcgaggaggcgaaacgcctgtttaacgatgcc
aacgacatgctcgacaggctaagcgcggagaaaaccctcaacccacgcggcgtggtgggg
ctgttcccggccaaccgcgtgggcgacgacatcgaaatttaccgcgatgaaacccgcact
cacgtgctggcggtcagccgccatctgcgccagcaaaccgagaaagtgggctttgccaac
tactgcctggccgattttgtcgcgccgaagctgagcggtaaagccgactatattggcgcc
tttgcggtaaccggcggtctggaagaagatgcgctggcggacgcgttcgaagcgcagtac
gatgattacaataaaatcatggtgaaagcgatcgccgaccgcctggcggaagccttcgcc
gagtacctgcacgagcgcgtgcgtaaggtgcactggggctacgcggcgaacgaaaacctc
agcaacgaggagctgatccgcgaaaactaccaggggattcgtccggcgccgggctatccg
gcctgcccggaacacaccgaaaagggcacgatctggcaactgctggacgtcgaagcccat
accgggatgaagctcaccgagtcgtacgccatgtggccgggcgcatccgtctccggctgg
tacttcagccacccggacagcaagtactttgccgtggcgcagcttcagcgcgatcagatt
gaagattacgccctgcgcaaaggcatgagcgtgtcagaagtagagcgctggctggcaccg
aacttaggctacgacgcagactaa
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