KEGG   Enterobacter hormaechei subsp. xiangfangensis 34399: LI66_01410
Entry
LI66_01410        CDS       T03707                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
eclx  Enterobacter hormaechei subsp. xiangfangensis 34399
Pathway
eclx00270  Cysteine and methionine metabolism
eclx00450  Selenocompound metabolism
eclx00670  One carbon pool by folate
eclx01100  Metabolic pathways
eclx01110  Biosynthesis of secondary metabolites
eclx01230  Biosynthesis of amino acids
eclx04981  Folate transport and metabolism
Module
eclx_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:eclx00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    LI66_01410 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    LI66_01410 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    LI66_01410 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    LI66_01410 (metH)
   04980 Cobalamin transport and metabolism
    LI66_01410 (metH)
Enzymes [BR:eclx01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     LI66_01410 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AJB80080
LinkDB
Position
292968..296651
AA seq 1227 aa
MSSKVEQLRAQLNERILVLDGGMGTMIQGYRLCEDDFRGERFADWPCDLKGNNDLLVLSK
PSVIRDIHNAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFEAAKLARACADEWTA
RTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIYAVKEEFESLGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LSFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSNAVAGLPPRKLPELPVACRLSGLEPLTIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDTFIHHAKLVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDATERMLDLAEKYRGSKSDESANVQQAEWRSWDVN
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVSLQAARENDLAFDWSSYTPPVAHRLGVQDVTACIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFKDANDMLDRLSAEKALNPRGVVGLFPANRVGDDVEIYRDETRT
HVLAVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAYDAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVHWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWKLLDVEAHTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQLQRDQI
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagtagagcaactgcgtgcgcagttaaatgaacgaattctggtgctggac
ggcggcatgggcaccatgatccagggctatcgtctgtgtgaagacgatttccgcggagag
cgctttgccgactggccttgtgacctgaaagggaacaatgacctgctggtgttgagtaaa
ccgtcagtcatcagagatatccacaacgcttacttcgaagcgggtgcggatattgtagaa
accaacaccttcaactcgacaaccatcgccatggcggattaccagatggagtccctgtcg
gcggagatcaactttgaagcggcgaagctggcgcgcgcctgcgccgacgaatggacggcc
cgtacgccggacaagccgcgctacgtagccggggtgctgggcccgaccaaccgcaccgcg
tcgatttctccggacgtgaacgacccggcgtttcggaacatcacgtttgaccagctggtg
gccgcgtatcgggagtccactaaagcgctggtggaaggcggctccgacctgatcctgatt
gaaaccgtattcgacaccctcaacgccaaagcggcaatttacgcggtaaaagaggagttc
gagtcgctgggcgtcgacctgccgatcatgatttccggtaccatcaccgatgcctcgggg
cgcacgctttccggccagacaaccgaagcgttttataactctctgcgccatgccgaagcg
ctctccttcggcctgaactgcgcgctggggccggacgagctgcgccagtacgtgcaggag
ctttcccgtatcgcggaatgctacgtcaccgcccacccgaacgccggtctgccgaacgcg
tttggtgagtacgatctggatgccgacaccatggcggcgcaaatccgcgaatgggctgaa
tctggtttcctcaacatcgtcggcggctgctgcggcaccacgcctgagcatatcgccgcc
atgagcaacgccgtcgccgggcttccaccgcgcaagctacccgagcttccggttgcctgt
cgcctgtccggcctggagccgttgaccatcggcgacgacagcctgtttgtgaacgtgggt
gaacgtactaacgttaccggctccgcgaagttcaagcgtctgatcaaagaagagaagtac
agcgaagcgctggacgttgcccgccagcaggtggaaagcggcgcgcaaattatcgatatc
aacatggacgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcaacctgatt
gccggtgagccggatatcgcccgcgtgccgatcatgattgactcttctaaatgggacgtc
atcgaaaaagggctgaagtgcattcagggcaaaggcatcgttaactccatctcgatgaaa
gagggggtcgatacctttatccaccacgcgaagctggtgcgtcgctacggggccgccgtg
gtggtgatggccttcgatgaagtgggtcaggccgatacccgcgagcgcaagattgagatt
tgccgccgcgcgtacaaaattttgaccgaagaggtgggcttcccgccggaagacatcatc
ttcgacccgaacatcttcgccgtcgcgaccggcatcgaagagcacaacaactacgcccag
gacttcatcggcgcgtgtgaagacattaaacgcgaactgccgcatgcgctgatctccggc
ggcgtgtcaaacgtctcgttctcgttccgcggcaacgacccggttcgtgaggcgatccac
gccgtgttcctctactatgccatccgcaacgggatggacatggggatcgtcaacgccggc
cagctggcaatttacgacgatctgccagccgagctgcgcgacgccgtagaagacgtgatc
ctcaatcgtcgtgacgacgccaccgaacgcatgctggatctggcggaaaaataccgcggc
agtaaatctgacgaatcagccaacgttcaacaggccgaatggcgctcctgggatgtgaat
aagcgtctggaatactcgctggtaaaaggcattaccgagtttatcgagcaggatactgag
gaagcgcgtcagcaggccgcccgtccgattgaagtgatcgaagggccgctgatggacggc
atgaacgtggtcggcgatctgtttggcgagggcaaaatgttcctgccgcaggtggtgaaa
tccgcccgcgtcatgaaacaggcggtggcgtatctggaaccctttatcgaagccagcaaa
gagaagggctccagtaacggtaaaatggtcatcgccaccgtgaagggcgacgtacacgac
atcggcaaaaacatcgttggcgtggtgttgcagtgtaataactacgaaattatcgatctt
ggcgtgatggtcccggcggataaaatcctcaggaccgcgcgcgaagtgaatgcggatttg
attggtctttccgggctgattacgccgtcgctggacgaaatggtcaacgtggcaaaagag
atggagcgccagggcttcaccattccactgctgattggcggggcaaccacctcgaaagcc
cacacggcggtgaaaatcgagcagaactacagcgggccgacggtgtatgtccaaaacgcc
tcgcgcaccgtgggcgtggtctccgcgctgctgtccgacacccagcgcgatgactttgtc
gcccgcacccgcaaagagtatgaaaccgtccgcattcagcatggacgtaagaaaccgcgc
acgccgccggtttcgcttcaggcggcgcgcgaaaacgatctggcgttcgactggtccagc
tatacgccgccggtcgcacaccgtctgggcgtgcaggacgtgacggcctgcatcgaaacg
ctgcgtaactacatcgactggacgccgttcttcatgacctggtcgctggcgggcaaatat
ccgcgcattcttgaagatgaggtggtgggcgaagaggcgaagcgcctgtttaaagatgct
aacgacatgctcgacaggctgagcgcagagaaagccctcaacccgcgcggcgtggtgggg
ctgttcccggcgaaccgcgtgggcgacgacgtggaaatctaccgcgatgaaacccgcacc
catgtgctggccgtgagccaccatctgcgccagcaaaccgagaaagtgggctttgccaac
tactgcctggcggatttcgtcgcaccgaaactctccggtaaagccgactatatcggcgcc
tttgccgtaaccggcggtctggaagaagacgcgctggcggatgcgtacgacgcgcagcat
gatgattacaacaaaatcatggtgaaagcgattgccgatcgcctggcggaagcctttgcc
gagtatctgcacgagcgcgtacgtaaggtgcactggggctacgcggccaatgagaatctc
agcaacgaggagctgatccgcgaaaattaccagggcattcgtccggcgccggggtatccg
gcctgcccggaacacaccgagaagggcactatctggaaactgctggacgtagaagcgcat
acgggcatgaagctcaccgagtcatttgccatgtggccgggcgcgtccgtttccggctgg
tacttcagccatccggacagcaagtacttcgccgtggcacagcttcagcgcgatcagatt
gaggattacgctctgcgtaaaggcatgagcgtgtcagaggtggaacgctggctggcgccg
aatttaggctacgacgcagactaa

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