Enterobacter hormaechei subsp. steigerwaltii: LI62_01820
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Entry
LI62_01820 CDS
T03708
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ecly
Enterobacter hormaechei subsp. steigerwaltii
Pathway
ecly00270
Cysteine and methionine metabolism
ecly00450
Selenocompound metabolism
ecly00670
One carbon pool by folate
ecly01100
Metabolic pathways
ecly01110
Biosynthesis of secondary metabolites
ecly01230
Biosynthesis of amino acids
ecly04981
Folate transport and metabolism
Module
ecly_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ecly00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LI62_01820 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
LI62_01820 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
LI62_01820 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
LI62_01820 (metH)
04980 Cobalamin transport and metabolism
LI62_01820 (metH)
Enzymes [BR:
ecly01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
LI62_01820 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AJB60855
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Position
320209..323892
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AA seq
1227 aa
AA seq
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MSSKVEQLRAQLNERILVLDGGMGTMIQGYRLSEDDFRGERFADWPCDLKGNNDLLVLSK
PSVIKDIHNAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFEAAKLARACADEWTA
RTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIYAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LSFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRKLPELPVACRLSGLEPLTIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDTFIHHAKLVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDATERMLDLAEKYRGSKSDESANVQQAEWRSWDVN
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVSLQAARDNDLAFDWSSYTPPVAHRLGVQDVTASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFKDANDMLDRLSAEKALNPRGVVGLFPANRVGDDVEIYRDETRT
HVLAVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAYDAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVHWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWKLLDVEAHTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQLQRDQI
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagtagagcaactgcgtgcgcagttaaatgaacgaattctggtgctggac
ggcggcatgggcaccatgatccagggctatcgtctgagtgaagacgatttccgcggcgag
cgctttgccgactggccttgtgacctgaaaggaaacaatgacctgctggtgttaagcaaa
ccgtctgtcatcaaggatatccacaacgcttacttcgaagcgggtgcggatattgttgaa
accaacaccttcaactcgacaaccatcgccatggcggattaccagatggaatccctgtcg
gcggagatcaactttgaagcggcgaagctggcgcgcgcctgcgccgacgaatggacggcc
cgtacgccggacaagccgcgctacgtagccggggtgctgggcccaaccaaccgcaccgcg
tcgatttctccggacgtcaacgacccggcgtttcggaacatcacctttgaccagctggtg
gccgcgtatcgtgagtccactaaagcgctggtggaaggcggttccgatctgatcctgatt
gaaaccgtattcgacaccctcaacgccaaagcggcaatttacgcggtgaaagaggagttc
gaggcgctgggcgttgacctgccgatcatgatttccggcaccatcactgacgcttctggc
cgtacactgtccggccagacaaccgaagcgttttataactccctgcgccacgccgaagcg
ctctccttcggcctgaactgcgcgctggggccggacgagctgcgccagtacgtgcaggag
ctttcgcgcatcgcagagtgctacgtcaccgcccacccgaacgccggtctgccgaacgcg
tttggtgagtacgatctggatgccgacaccatggcggcgcaaatccgcgaatgggccgaa
tctggtttcctcaacatcgtcggcggctgctgcggcaccacgccggagcatatcgccgcc
atgagccgcgccgtcgccgggcttccaccgcgcaagctacccgagcttccggtagcctgt
cgtctgtccggcctggagccgttgaccatcggcgacgacagcctgtttgtgaacgtgggt
gaacgtactaacgttaccggttctgcgaagttcaagcgcctgatcaaagaagagaagtac
agcgaagcgctggacgttgctcgccagcaggtggaaagcggcgcgcagattatcgatatc
aacatggacgaggggatgcttgatgccgaagcggcaatggtgcgtttcctcaacctgatt
gccggtgagccggatatcgcccgcgtgccgatcatgattgactcttccaaatgggaagtc
atcgaaaaagggctgaagtgcattcagggcaaaggcatcgttaactccatttcgatgaaa
gagggcgtcgatacctttatccaccacgcgaagctggtccgtcgctacggagccgccgtg
gtggtgatggccttcgatgaagtgggccaggccgatacccgcgagcgcaagattgagatt
tgccgccgcgcgtacaaaattttgaccgaagaggtgggcttcccgccggaagacatcatc
ttcgacccgaacatcttcgccgtcgcgaccggcatcgaagagcacaacaactacgcccag
gactttatcggcgcgtgtgaagacattaaacgcgagctaccgcatgcgctgatctccggc
ggcgtgtcaaacgtgtcgttctcgttccgcggcaacgacccggtgcgtgaggcgatccac
gccgtattcctctactacgccatccgcaacgggatggacatggggatcgtcaacgccggc
cagctggcaatttacgacgatctgccagccgagctgcgcgacgccgtagaagacgtgatc
ctcaatcgtcgtgacgacgccaccgaacgcatgctggatctggcggaaaaataccgcggc
agtaaatctgacgaatcagccaacgttcaacaggccgaatggcgctcctgggatgtgaat
aagcgtctggaatactcgctggtaaaaggcattaccgagtttatcgagcaggataccgag
gaagcgcgtcagcaggccgcccgtccgattgaagtgatcgaagggccgctgatggacggc
atgaacgtggtcggcgatctgttcggcgagggcaaaatgttcctgccgcaggtggtgaaa
tccgcccgcgtcatgaagcaggcagtggcgtatctggaaccctttatcgaagccagcaaa
gagaagggctccagtaacggtaaaatggtcatcgccaccgtgaagggcgacgtacacgac
atcggcaaaaacatcgttggcgtggtgttgcagtgtaataactacgaaattatcgatctt
ggcgtgatggtcccggcggataaaatcctcaggaccgcgcgcgaagtgaatgcggatctg
attggtctttccgggctgattacgccttcgcttgacgaaatggtcaacgtggcaaaagag
atggagcgccagggctttaccattccgctgctgattggcggggcaaccacctcgaaagcc
cacacggcggtgaaaatcgagcagaactacagtgggccgacggtgtatgtccaaaacgcc
tcgcgcaccgtgggcgtggtctccgcgctgctgtccgacacccagcgcgatgattttgtc
gcccgcacccgcaaagagtatgaaaccgtccgcattcagcatggacgtaagaaaccgcgc
acgccgccggtttcgcttcaggcggcgcgcgataacgatctggcgttcgactggtccagc
tatacgccgccggtcgcacaccgtctgggcgtgcaggacgtgacggccagcatcgaaacg
ctgcgtaactacatcgactggacgccgttcttcatgacctggtcgctggcgggcaaatat
ccgcgcattcttgaagatgaggtggtgggcgaagaggcgaagcgcctgtttaaagatgct
aacgacatgctcgacaggctgagcgcagagaaagccctcaacccgcgcggcgtggtgggg
ctgttcccggcgaaccgcgtgggcgacgacgtggaaatctaccgcgatgaaacccgcacc
cacgtgctggccgtgagccaccacctgcgccagcaaaccgagaaagtgggctttgccaac
tactgcctggcggatttcgtcgcaccgaaactctccggtaaagccgactatatcggcgcc
tttgccgtaaccggtggtctggaagaagacgcgctggcggatgcgtacgacgcgcagcac
gatgattacaacaaaatcatggtgaaagcgatcgccgaccgtctggcggaagccttcgct
gaatatctgcatgaacgcgtacgtaaggtgcactggggctacgcggcgaatgagaacctc
agcaacgaggagctgatccgcgaaaactaccagggcattcgtccggcgccggggtatccg
gcctgcccggaacacaccgagaagggcactatctggaagttgctggacgtcgaagcgcat
accggcatgaagctcaccgagtcgttcgccatgtggccgggcgcgtccgtttccggctgg
tacttcagccatccggacagcaagtacttcgccgtggcacagcttcagcgcgatcagatt
gaggattacgccctgcgtaaaggcatgagcgtgtcagaggtggaacgctggctggcgccg
aatttgggctacgacgcagactaa
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