Enterobacter hormaechei subsp. hormaechei: LI64_01545
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Entry
LI64_01545 CDS
T03709
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
eclz
Enterobacter hormaechei subsp. hormaechei
Pathway
eclz00270
Cysteine and methionine metabolism
eclz00450
Selenocompound metabolism
eclz00670
One carbon pool by folate
eclz01100
Metabolic pathways
eclz01110
Biosynthesis of secondary metabolites
eclz01230
Biosynthesis of amino acids
eclz04981
Folate transport and metabolism
Module
eclz_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
eclz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LI64_01545 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
LI64_01545 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
LI64_01545 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
LI64_01545 (metH)
04980 Cobalamin transport and metabolism
LI64_01545 (metH)
Enzymes [BR:
eclz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
LI64_01545 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AJB69315
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All DBs
Position
319504..323187
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AA seq
1227 aa
AA seq
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MSSKVEQLRAQLNERILVLDGGMGTMIQGYRLSEDDFRGERFADWPCDLKGNNDLLVLSK
PSVIRDIHNAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFEAARLARACADEWTA
RTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIYAVKEEFEALGIDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LSFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRKLPELPVACRLSGLEPLTIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDTFIHHAKRVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDATERMLDLAEKYRGSKSDESANVQQAEWRAWDVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGRMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILKTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVSLQAARDNDLAFDWSSYTPPVAHRLGVQDVTASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFKDANDMLDRLSAEKALNPRGVVGLFPANRVGDDVEIYRDETRT
HVLAVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFDAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVHWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWKLLDVEAHTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQLQRDQI
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagtagagcaactgcgtgcgcagttaaatgaacgaattctggtgctggac
ggcggcatgggcaccatgatccagggctatcgtctgagtgaagacgatttccgcggcgag
cgctttgccgactggccttgcgacctgaaaggaaacaatgacctgctggtgttgagcaaa
ccgtccgtcatcagggatatccacaacgcctactttgaagcgggcgcggatatcgttgaa
accaacacctttaactcgacaaccatcgccatggcagattaccagatggaatccctgtcg
gcggagatcaactttgaagcggccagactcgcccgcgcctgcgccgacgagtggacggcc
cgcacgccggacaagccgcgctacgttgccggggtgcttggcccaaccaaccgcaccgcg
tcgatttcaccggacgtcaacgatccggcgtttcgcaatatcacctttgaccagctggtt
gcggcctaccgtgaatcgaccaaagcgctggtggaaggcggctctgacctgatcctgatt
gaaaccgtattcgataccctcaacgctaaagccgcgatttacgcggtgaaagaggagttc
gaggcgctgggcattgacctgccgatcatgatttccggcaccatcaccgacgcctcaggc
cgcaccctgtccgggcagacaaccgaagcgttttacaactccctgcgccacgccgaagcg
ctctccttcggcctgaactgcgcgctggggccagacgaactgcgccagtacgtgcaggag
ctttcgcgcattgcagagtgctacgtcaccgcccacccgaacgccggtctgccgaacgcg
tttggcgagtacgatctggatgccgacaccatggcggcgcaaatccgcgagtgggccgag
tctggcttcctcaacattgtcggcggttgctgcggcaccacgccggagcatatcgccgcc
atgagccgcgccgtcgccgggcttccgccgcgcaagctgcccgagcttccggttgcctgt
cgcctttccggccttgagccgttaaccattggcgacgatagcctgtttgtgaacgtgggt
gaacgtacaaacgttaccggttccgcgaagttcaagcgcctgatcaaagaagagaagtac
agcgaagcgctggacgttgcccgccagcaggtggaaagcggggcgcagatcatcgatatc
aatatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcaacctgatc
gccggtgagccggatatcgcccgcgtgccgatcatgattgactcttccaaatgggacgtc
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgttaactccatctcgatgaaa
gagggcgtcgatacctttatccaccacgcgaagagggtgcgccgctacggtgccgccgtg
gtggtcatggcctttgacgaagtgggtcaggccgatacccgcgagcgcaaaatcgagatt
tgccgccgcgcgtacaaaattctgaccgaagaggtgggcttcccgccggaagacattatc
ttcgacccgaacatcttcgccgtcgcgaccgggattgaagagcacaacaactacgcccag
gactttatcggtgcgtgtgaggacattaaacgcgagctgccgcacgcgctgatctccggc
ggcgtgtctaacgtgtcgttctcgttccgcggcaacgacccggtgcgcgaagcgatccac
gccgtgttcctctactacgccatccgcaacgggatggatatggggatcgtcaacgccggc
cagctggcgatttacgacgatctgcctgccgagctgcgcgacgccgtagaagacgtcatc
ctcaatcgtcgtgacgatgccaccgagcgcatgctggatctggcggagaaataccgcggc
agtaaatctgacgaatcagccaacgttcagcaggccgaatggcgcgcctgggacgtgaaa
aagcgtctggaatattcgctggtaaaaggcattaccgagttcatcgagcaggatactgaa
gaggcgcgtcagcaggccgcccgtccgattgaagtgatcgaagggccgctgatggacggc
atgaacgtggtcggcgatctgttcggcgagggcaaaatgttcctgccgcaggtggtgaaa
tctgcccgcgtgatgaagcaggccgtcgcttatctggagccgtttatcgaggccagcaaa
gagaaaggctccagcaacggcaggatggttatcgccaccgtgaagggcgacgtgcacgac
atcggcaagaatatcgtcggggtggtgctgcagtgcaataactatgaaattatcgacctg
ggcgtgatggtcccggcggacaaaatcctcaagaccgcgcgcgaagtgaatgcggatctg
attggtctttccgggttgatcacgccgtcgctggacgaaatggtcaacgtagcaaaagag
atggagcgtcagggcttcaccattccgctgctgattggcggggcgaccacctcgaaagcg
cacacggcagtgaagatcgagcagaactacagcggcccgacggtgtatgtgcagaacgcc
tcgcgcaccgtgggcgtggtctccgcgctgctgtcggacacccagcgcgatgattttgtg
gcgcgcacccgcaaagagtacgaaaccgtccgcattcagcatggtcgcaagaaaccgcgt
accccgccggtttcacttcaggcagcgcgcgataacgatctggcgttcgactggtccagc
tatacgccgccggtcgcgcaccgtctgggcgtgcaggacgtgacggccagcatcgaaacg
ctgcgaaactacatcgactggacgccgttctttatgacctggtcgctggcgggcaaatat
ccgcgcattcttgaagatgaggtggtgggcgaagaggcgaagcgtctgtttaaagatgcc
aacgacatgctcgacagacttagcgcagaaaaagccctcaacccgcgcggggtggtgggg
ctgtttccggcgaaccgcgtgggcgacgacgtggaaatctaccgcgatgaaacccgcacc
cacgtgctggccgtgagccatcacctgcgccagcaaaccgagaaagtgggctttgccaac
tattgcctggcggatttcgtcgcgccgaagctgagcggtaaagccgactatatcggcgcg
tttgccgtaaccggtggtctggaagaagacgcgctggcggatgcgttcgacgcgcagcac
gatgattacaacaaaatcatggtgaaagcgattgccgatcgcctggcggaagcgttcgcc
gagtacctccacgagcgcgtgcgcaaggtgcactggggctatgcggcgaatgagaacctc
agcaacgaggagctgatccgcgaaaactaccagggcattcgtccggcgccgggttatccg
gcctgcccggaacacaccgagaagggcaccatctggaaactgctcgacgtcgaagcgcat
acggggatgaaacttaccgagtcgttcgccatgtggccgggcgcgtccgtttccggctgg
tatttcagccacccggacagcaagtacttcgccgtggcacagcttcagcgcgatcagatt
gaggattacgccctgcgtaaaggcatgagcgtgtcagaggtagaacgctggctggcgccg
aatttaggctacgacgcagactaa
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