Escherichia coli SMS-3-5 (environmental): EcSMS35_A0121
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Entry
EcSMS35_A0121 CDS
T00672
Symbol
dhfrV
Name
(GenBank) dihydrofolate reductase type 5
KO
K18589
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
Organism
ecm
Escherichia coli SMS-3-5 (environmental)
Pathway
ecm00670
One carbon pool by folate
ecm00790
Folate biosynthesis
ecm01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
ecm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EcSMS35_A0121 (dhfrV)
00670 One carbon pool by folate
EcSMS35_A0121 (dhfrV)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes [BR:
ecm01504
]
EcSMS35_A0121 (dhfrV)
Enzymes [BR:
ecm01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
EcSMS35_A0121 (dhfrV)
Antimicrobial resistance genes [BR:
ecm01504
]
Gene variants
Trimethoprim resistance genes
Dihydrofolate reductases
EcSMS35_A0121 (dhfrV)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DHFR_1
Motif
Other DBs
NCBI-ProteinID:
ACB20295
UniProt:
B1LRU7
LinkDB
All DBs
Position
pSMS35_130:91389..91871
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AA seq
160 aa
AA seq
DB search
MRTLKVSLMAAKAKNGVIGCGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNR
KYAVVTRSGWTSNDDNVVVFQSIEEAMDRLAEFTGHVIVSGGGEIYRETLPMASTLHLST
IDIEPEGDVFFPSIPNTFEVVFEQHFTSNINYCYQIWKKG
NT seq
483 nt
NT seq
+upstream
nt +downstream
nt
atgagaaccttgaaagtatcattgatggctgcgaaagcgaaaaacggcgtgattggttgc
ggtccagacataccctggtccgcgaaaggggagcagctactttttaaagcattgacctac
aatcagtggcttctggtgggtcgcaagacgtttgaatctatgggcgcactccccaatagg
aaatacgcggtcgttacccgctcaggttggacatcaaatgatgacaatgtagttgtattt
cagtcaatcgaagaggccatggacaggctagctgaattcaccggtcacgttatagtgtct
ggtggcggagaaatttaccgagaaacattacccatggcctctacgctccacttatcgacg
atcgacatcgagccagagggggatgttttcttcccgagtattccaaataccttcgaagtt
gtttttgagcaacactttacttcaaacattaactattgctatcaaatttggaaaaagggt
taa
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