Escherichia coli K-12 MG1655: b0048 Help Entry b0048             CDS       T00007                                  Symbol folA Name (RefSeq) dihydrofolate reductase   KO K00287   dihydrofolate reductase [EC:1.5.1.3] Organism eco  Escherichia coli K-12 MG1655 Pathway eco00670   One carbon pool by folate eco00790   Folate biosynthesis eco01100   Metabolic pathways eco01240   Biosynthesis of cofactors eco04981   Folate transport and metabolism Module eco_M00126   Tetrahydrofolate biosynthesis, GTP => THF Brite KEGG Orthology (KO) [BR:eco00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     b0048 (folA)    00670 One carbon pool by folate     b0048 (folA)  09150 Organismal Systems   09154 Digestive system    04981 Folate transport and metabolism     b0048 (folA) Enzymes [BR:eco01000]  1. Oxidoreductases   1.5  Acting on the CH-NH group of donors    1.5.1  With NAD+ or NADP+ as acceptor     1.5.1.3  dihydrofolate reductase      b0048 (folA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DHFR_1 Motif Other DBs NCBI-GeneID:  944790 NCBI-ProteinID:  NP_414590 Pasteur:  folA RegulonDB:  RDBECOLIGNC00320 ECOCYC:  EG10326 ASAP:  ABE-0000164 UniProt:  P0ABQ4 Structure PDBPDBj LinkDB All DBs Position 49823..50302 Genome browser AA seq 159 aa AA seqDB search MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR NT seq 480 nt NT seq  +upstreamnt  +downstreamnt atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg attatgggccgccatacctgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat gaacagttcttgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc cacgatgctgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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