KEGG   Escherichia coli O18 K1 PMV-1 (ExPEC): ECOPMV1_00049
Entry
ECOPMV1_00049     CDS       T02847                                 
Symbol
folA
Name
(GenBank) Dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecoi  Escherichia coli O18:K1 PMV-1 (ExPEC)
Pathway
ecoi00670  One carbon pool by folate
ecoi00790  Folate biosynthesis
ecoi01100  Metabolic pathways
ecoi01240  Biosynthesis of cofactors
ecoi04981  Folate transport and metabolism
Module
ecoi_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecoi00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    ECOPMV1_00049 (folA)
   00670 One carbon pool by folate
    ECOPMV1_00049 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ECOPMV1_00049 (folA)
Enzymes [BR:ecoi01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     ECOPMV1_00049 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: CDH63585
LinkDB
Position
52471..53061
AA seq 196 aa
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWN
LPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIA
ACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDA
DAQNSHSYCFEILERR
NT seq 591 nt   +upstreamnt  +downstreamnt
gtggactcgccagcagaatataaaattttcctcaacatcatcctcgcaccagtcgacgac
ggtttacgctttacgtatagtggcgacaattttttttatcgggaaatctcaatgatcagt
ctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatgccgtggaac
ctgcctgccgatctcgcctggtttaaacgcaacactttaaataaacccgtgattatgggc
cgccatacctgggaatccatcggtcgtccgttgccaggacgcaaaaatattatcctcagc
agtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaagccattgcg
gcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttatgagcagttc
ctgccgaaagcgcaaaaactgtatctgacgcatatcgacgcggaagtggaaggcgacacc
catttcccggattacgagccggatgactgggaatcggtattcagtgaattccacgacgcc
gatgcgcagaactctcatagctattgctttgagattctggagcggcggtaa

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