KEGG   Escherichia coli JJ1886: P423_00240
Entry
P423_00240        CDS       T02896                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecoj  Escherichia coli JJ1886
Pathway
ecoj00670  One carbon pool by folate
ecoj00790  Folate biosynthesis
ecoj01100  Metabolic pathways
ecoj01240  Biosynthesis of cofactors
ecoj04981  Folate transport and metabolism
Module
ecoj_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecoj00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    P423_00240 (folA)
   00670 One carbon pool by folate
    P423_00240 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    P423_00240 (folA)
Enzymes [BR:ecoj01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     P423_00240 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AGY83094
LinkDB
Position
55261..55851
AA seq 196 aa
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWN
LPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIA
ACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDA
DAQNSHSYCFEILERR
NT seq 591 nt   +upstreamnt  +downstreamnt
gtggactcgccagcagaatataaaattttcctcaacatcatcctcgcaccagtcgacgac
ggtttacgctttacgtatagtggcgacaattttttttatcgggaaatctcaatgatcagt
ctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatgccgtggaac
ctgcctgccgatctcgcctggtttaaacgcaacactttaaataaacccgtgattatgggc
cgccatacctgggaatccatcggtcgtccgttgccaggacgcaaaaatattatcctcagc
agtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaagccattgcg
gcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttatgagcagttc
ctgccgaaagcgcaaaaactgtatctgacgcatatcgacgcggaagtggaaggcgacacc
catttcccggattacgagccggatgactgggaatcggtattcagtgaattccacgacgcc
gatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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