Escherichia coli O81 ED1a (commensal): ECED1_4725
Help
Entry
ECED1_4725 CDS
T00827
Symbol
metH
Name
(GenBank) homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ecq
Escherichia coli O81 ED1a (commensal)
Pathway
ecq00270
Cysteine and methionine metabolism
ecq00450
Selenocompound metabolism
ecq00670
One carbon pool by folate
ecq01100
Metabolic pathways
ecq01110
Biosynthesis of secondary metabolites
ecq01230
Biosynthesis of amino acids
ecq04981
Folate transport and metabolism
Module
ecq_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ecq00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ECED1_4725 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
ECED1_4725 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
ECED1_4725 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
ECED1_4725 (metH)
04980 Cobalamin transport and metabolism
ECED1_4725 (metH)
Enzymes [BR:
ecq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
ECED1_4725 (metH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
CAR10686
UniProt:
B7N2L7
LinkDB
All DBs
Position
4680678..4684361
Genome browser
AA seq
1227 aa
AA seq
DB search
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGEDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPAEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPTELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDDTANTQQAEWRSWEVN
KRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKMLNPRGVVGLFPANRVGDDIEIYRDETRT
HVINVSHHLRQQTEKTGFANYCLADFVAPKVSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYP
ACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDYARRKGMSVTEVERWLAPNLGYDAE
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagtggaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcaccatgatccagagctatcgactgaacgaagccgattttcgaggtgaa
cgctttgccgactggccatgcgatctcaaaggtaacaacgacctgctggtgctcagcaaa
ccggaagtgatcgccgctatccacaacgcctactttgaagcgggcgcggatatcatcgaa
accaacaccttcaactccacgaccattgcgatggcggattaccagatggaatccctgtcg
gcggaaatcaactttgcagcggcgaaactggcgcgcgcctgtgccgacgagtggactgcc
cgcacgccggagaaaccgcgctacgttgccggtgttctcggcccgaccaaccgcacggcg
tctatttctccggacgtcaacgatccggcattccgcaacatcacttttgaccagctggtg
gcggcttatcgagaatccaccaaagcgctggtggaaggtggcgcggacctgatcctgatt
gaaaccgttttcgacacccttaacgccaaagcggcggtctttgcggtgaaaacggagttt
gaagcgctgggcgttgaactgccgattatgatctccggcaccatcaccgacgcctccggg
cgcacgctctccgggcagactactgaagcgttttacaactccctgcgccacgccgaagcg
ctgacctttggcctgaactgtgcgctggggccagacgaactgcgccagtacgtacaggaa
ctgtcgcgtattgcggaatgctacgtcaccgcccacccgaacgccgggctgcccaacgcc
tttggtgaatacgatctcgacgccgacacgatggcaaaacagatacgtgaatgggcagaa
gcaggctttctcaatatcgtcggcggctgctgcggcaccacgccacaacatattgcagcg
atgagtcgtgcagtagaaggattagcgccgcgcaaactaccggaaattcccgtagcctgc
cgtttgtccggcctggagccgctgaacattggcgaagatagcctgtttgtgaacgtgggt
gaacgcaccaacgtcaccggttccgctaagttcaagcgactgatcaaagaagagaaatac
agcgaggcgctggatgtggcgcgtcagcaggtggaaaacggtgcgcagattatcgatatc
aacatggatgaagggatgctcgacgccgaagcggcgatggtgcgttttctcaatctgatt
gccggtgaaccggatatcgctcgcgtgccgattatgatcgactcctcaaaatgggacgtt
attgaaaaaggtctgaagtgtatccagggcaaaggcattgttaactctatctcgatgaaa
gagggtgtcgacgcctttatccatcacgcgaaactgttgcgtcgctacggtgcggcagtc
gtggtaatggcttttgacgaacagggccaggccgatacccgcgcacggaaaatcgagatt
tgccgtcgggcgtacaaaatcctcaccgaagaggttggcttcccggctgaagatatcatc
ttcgacccgaacatcttcgcggtcgcaactggcattgaagagcacaacaattacgcgcag
gactttatcggcgcgtgtgaagacatcaaacgtgaactgccgcacgcactgatttccggc
ggcgtttctaacgtttctttctcattccgtggcaacgatccggtgcgcgaagccattcac
gcggtgttcctctactacgctattcgcaatggcatggatatggggatcgtcaacgccggg
caactggcgatttacgacgacctgcctaccgagctacgcgacgcggtggaggatgtgatc
ctcaaccgtcgcgacgatggcaccgagcgtttactcgagcttgccgagaaatatcgcggc
agcaaaaccgacgacaccgctaacacccagcaggcggagtggcgctcgtgggaagtgaat
aaacgtctggaatactcgctggtcaaaggcattaccgagtttatcgagcaggataccgaa
gaagcccgccagcaggctacgcgtccgattgaagtgattgaaggcccgttgatggacggc
atgaacgtggtcggcgacctgtttggcgagggcaaaatgttcctgccgcaggtggtgaaa
tcggcgcgcgtaatgaagcaggcggtggcgtatctcgaaccgtttattgaagccagcaaa
gagcagggtaaaaccaacggcaagatggtgatcgccaccgtgaaaggcgatgtccacgac
atcggtaaaaatatcgttggcgtggtgctgcaatgtaacaactacgaaattgtcgatctc
ggcgtgatggtgcctgcggaaaaaattctccgtaccgctaaagaagtgaatgctgatttg
attggcctttcagggctgatcacgccgtcgctggacgagatggttaacgtggcgaaagag
atggagcgtcagggcttcaccattccgctattgattggcggcgcgaccacctcaaaagcg
cacacggcggtgaaaatcgagcagaactacagcggcccgacggtgtatgtgcagaacgca
tcgcgcaccgttggtgtggtggcggcgctgctttccgacactcagcgcgatgatttcgtt
gctcgtacccgcaaggagtacgaaaccgtgcgtattcagcacggacgaaagaaaccacgc
acaccaccggtcacgctggaagcggcgcgtgataacgacttcgcttttgactggcaggct
tacacgccgccggtggcgcaccgtctcggtgtgcaggaagtcgaagccagcatcgaaacg
ctgcgtaattacatcgactggacgccgttctttatgacctggtcgctggccgggaagtat
ccgcgcattctggaagatgaagtggtaggtgttgaggcgcagcggctgtttaaagacgcc
aacgacatgctggataaattaagcgccgaaaaaatgctgaacccgcgtggtgtggtgggc
ctgttcccggcaaaccgtgtgggcgatgacattgaaatctaccgtgacgaaacgcgtacc
catgtgattaatgtcagccaccatctacgccaacagaccgaaaaaaccggcttcgctaac
tactgtctcgctgacttcgttgcgccgaaggtttccggcaaagcagattacatcggcgca
tttgccgtgactggcgggctggaagaggacgcactagctgatgcctttgaagcacagcat
gatgattacaacaaaatcatggtgaaagcgcttgccgaccgtctggcggaagcctttgcg
gagtatctccatgagcgtgtgcgtaaagtctactggggctatgcgccgaacgagaacctc
agcaacgaagagctgatccgcgaaaactaccagggcatccgtccggcaccgggctaccct
gcctgcccggaacatacggaaaaagccacaatctgggagctgctggaagtggaaaaacat
accggtatgaaactcacggaatccttcgccatgtggccgggtgcatcggtttcgggttgg
tacttcagtcatccagacagcaagtattacgcggtggcgcaaattcagcgcgatcaggtt
gaagactatgcccgccgtaaaggaatgagcgttaccgaagttgagcgttggttggcaccg
aatctggggtatgatgccgagtaa
DBGET
integrated database retrieval system
