KEGG   Escherichia coli O8 IAI1 (commensal): ECIAI1_0465
Entry
ECIAI1_0465       CDS       T00828                                 
Symbol
acrB
Name
(GenBank) multidrug efflux system protein
  KO
K18138  multidrug efflux pump
Organism
ecr  Escherichia coli O8 IAI1 (commensal)
Pathway
ecr01501  beta-Lactam resistance
ecr01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:ecr00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    ECIAI1_0465 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    ECIAI1_0465 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ecr02000]
    ECIAI1_0465 (acrB)
   01504 Antimicrobial resistance genes [BR:ecr01504]
    ECIAI1_0465 (acrB)
Transporters [BR:ecr02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   ECIAI1_0465 (acrB)
Antimicrobial resistance genes [BR:ecr01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    ECIAI1_0465 (acrB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF_C
Other DBs
NCBI-ProteinID: CAQ97337
LinkDB
Position
complement(496011..499160)
AA seq 1049 aa
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT
VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ
EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS
QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL
TSTEEFGKILLKVNQDGSRVLLRDVAKIELGVENYDIIAEFNGQPASGLGIKLATGANAL
DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ
NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR
YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT
KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD
AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG
LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR
MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA
MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS
VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL
IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF
FVPVFFVVVRRRFSRKNEDIEHSHTVDHH
NT seq 3150 nt   +upstreamnt  +downstreamnt
atgcctaatttctttatcgatcgcccgatttttgcgtgggtgatcgccattatcatcatg
ttggcaggggggctggcgatcctcaaactgccggtggcgcaatatcctacgattgcaccg
ccggcagtaacgatctccgcctcctaccccggcgctgatgcgaaaacagtgcaggacacg
gtgacacaggttatcgaacagaatatgaacggtatcgataacctgatgtacatgtcctct
aacagtgactccacgggtaccgtgcagatcaccctgacctttgagtctggtactgatgcg
gatatcgcgcaggttcaggtgcagaacaaactgcagctggcgatgccgttgctgccgcaa
gaagttcagcagcaaggggtgagcgttgagaaatcatccagcagcttcctgatggttgtc
ggcgttatcaacaccgatggcaccatgacgcaggaggatatctctgactacgtagcggcg
aatatgaaagatgccatcagccgtacgtcgggcgtgggtgatgttcagttgttcggttca
cagtacgcgatgcgtatctggatgaacccgaatgagctgaacaaattccagctaacgccg
gttgatgtcattaccgccatcaaagcgcagaacgcccaggttgcggcgggtcagctcggt
ggtacgccgccggtgaaaggccaacagcttaacgcctctattattgctcagacgcgtctg
acctctactgaagagttcggcaaaatcctgctgaaagtgaatcaggatggttcccgcgta
ctgctgcgtgatgtggcgaagattgagctgggtgttgagaactacgacatcatcgcagag
tttaacggccaaccggcttccggtctggggatcaagctggcgaccggtgcaaacgcgctg
gataccgctgcggcaatccgtgctgaactggcgaagatggaaccgttcttcccgtcgggt
ctgaaaattgtttacccgtacgacaccacgccgttcgtgaaaatctctattcacgaagtg
gttaaaacgctggtcgaagcgatcatcctcgtgttcctggttatgtatctgttcctgcag
aacttccgcgcgacgttgattccgaccattgccgtaccggtggtattgctcgggaccttt
gccgtccttgccgcctttggcttctcgataaacacgctaacaatgttcgggatggtgctc
gccatcggcttgttggtggatgacgctatcgttgtggtagaaaacgtggagcgtgttatg
gcggaagaaggtttgccgccaaaagaagctacccgtaagtcgatggggcagattcagggc
gctctggtcggtatcgcgatggtactgtcagcggtattcgtaccgatggccttctttggc
ggttctactggtgctatctatcgtcagttctctattaccattgtttcagcaatggcgctg
tcggtactggtagcgttgatcctgactccggctctttgtgccaccatgctgaaaccgatt
gccaaaggcgatcacggggaaggtaaaaaaggcttcttcggctggtttaaccgcatgttc
gagaagagcacgcaccactacaccgacagcgtaggcggtattctgcgcagtacggggcgt
tacctggtgctgtatctgatcatcgtggtcggcatggcctatctgttcgtgcgtctgcca
agctccttcttgccagatgaggaccagggcgtatttatgaccatggttcagctgccagca
ggtgcaacgcaggaacgtacacagaaagtgctcaatgaggtaacgcattactatctgacc
aaagaaaagaacaacgttgagtcggtgttcgccgttaacggcttcggctttgcgggacgt
ggtcagaataccggtattgcgttcgtttccttgaaggactgggccgatcgtccgggcgaa
gaaaacaaagttgaagcgattaccatgcgtgcaacacgcgctttctcgcaaatcaaagat
gcgatggttttcgcctttaacctgcccgcaatcgtggaactgggtactgcaaccggcttt
gactttgagctgattgaccaggctggccttggtcacgaaaaactgactcaggcgcgtaac
cagttgcttgcagaagcagcgaagcaccctgatatgttgaccagcgtacgtccaaacggt
ctggaagataccccgcagtttaagattgatatcgaccaggaaaaagcgcaggcgctgggt
gtttctatcaatgacattaacaccactctgggcgctgcatggggcggtagctatgtgaac
gactttatcgaccgcggtcgtgtgaagaaagtttacgtcatgtcagaagcgaaataccgt
atgctgccggatgatatcggcgactggtatgttcgtgctgctgatggtcagatggtgccg
ttctcggcattctcctcttctcgttgggagtacggttcgccgcgtctggaacgttacaat
ggcctgccatccatggaaatcttaggccaggcggcaccgggtaaaagtaccggtgaagca
atggagctgatggaacaactggcgagcaaactgcctaccggtgttggctatgactggacg
gggatgtcctatcaggaacgcctctccggcaaccaggcaccttcactgtacgcgatttcg
ttgattgtcgtattcctgtgtctggcggcgctgtacgagagctggtcgattccgttctcc
gttatgctggtcgttccgctgggggttatcggtgcgttgctggctgccaccttccgtggc
ctgaccaatgacgtttacttccaggtaggcctgctcacaaccattgggttgtcggcgaag
aacgcgatacttatcgtcgaattcgccaaagacttgatggataaagaaggtaaaggtctg
attgaagcgacgcttgatgcagtgcggatgcgtttacgtccgatcctgatgacctcgctg
gcgtttatcctcggcgttatgccgctggttatcagtactggtgctggttccggcgcgcag
aacgcagtaggtaccggtgtaatgggcgggatggtgaccgcaacggtactggcaatcttc
ttcgttccggtattctttgtggtggttcgccgccgctttagccgcaagaatgaagatatc
gagcacagccatactgtcgatcatcattga

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