KEGG   Escherichia coli O8 IAI1 (commensal): ECIAI1_2469
Entry
ECIAI1_2469       CDS       T00828                                 
Symbol
ligA
Name
(GenBank) DNA ligase, NAD(+)-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
ecr  Escherichia coli O8 IAI1 (commensal)
Pathway
ecr03030  DNA replication
ecr03410  Base excision repair
ecr03420  Nucleotide excision repair
ecr03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:ecr00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    ECIAI1_2469 (ligA)
   03410 Base excision repair
    ECIAI1_2469 (ligA)
   03420 Nucleotide excision repair
    ECIAI1_2469 (ligA)
   03430 Mismatch repair
    ECIAI1_2469 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ecr03032]
    ECIAI1_2469 (ligA)
   03400 DNA repair and recombination proteins [BR:ecr03400]
    ECIAI1_2469 (ligA)
Enzymes [BR:ecr01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     ECIAI1_2469 (ligA)
DNA replication proteins [BR:ecr03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     ECIAI1_2469 (ligA)
DNA repair and recombination proteins [BR:ecr03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     ECIAI1_2469 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     ECIAI1_2469 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     ECIAI1_2469 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      ECIAI1_2469 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia DNA_ligase_ZBD HHH PTCB-BRCT RNA_ligase PUA_2 Prok-E2_C DZR_2 Zn_ribbon_NUD
Other DBs
NCBI-ProteinID: CAQ99309
UniProt: B7M6S1
LinkDB
Position
complement(2559725..2561740)
AA seq 671 aa
MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQ
RVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLA
VSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAG
FEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHL
GRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLEQQEQL
GFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHN
ADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEG
EAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAG
KLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEA
ASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAG
KTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVI
DEAEMLRLLGS
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggaatcaatcgaacaacaactgacagaactgcgaacgacgcttcgccatcatgaatat
ctttatcatgtgatggatgcgccggaaattcccgacgctgaatacgacaggctgatgcgc
gaactgcgcgagctggaaaccaaacatccagaactgattacgcctgattcgcctacccaa
cgtgtaggcgctgcgccgctggcggctttcagccagatacgccatgaagtaccaatgctg
tcactggataacgtttttgatgaagaaagctttcttgctttcaacaaacgtgtgcaggac
cgtctgaaaaacaacgagaaagtcacctggtgctgtgagctgaagctggatggccttgcc
gtcagtattctgtatgaaaatggcgttttagtcagtgccgcgacccgtggcgatggcacc
accggggaagatatcacgtctaatgtgcgtactattcgcgctattccgctgaagctgcac
ggagagaatatcccggcgcgtctggaagtgcgtggtgaagtgttcctgccgcaggcgggg
ttcgaaaagattaacgaagatgcgcgacgcacgggcgggaaagtttttgctaacccacgt
aatgcggcagctggttcactgcgtcagcttgatccgcgtattacagcgaagcgaccgctc
acttttttctgctatggcgttggtgttctggaaggtggcgagctgccggatactcatctt
ggccgtttactgcaatttaaaaagtgggggttgccggtcagcgatcgggtaacgctttgt
gaatcggcggaagaagtgctggcgttctatcacaaagtggaagaagaccgcccgacgctg
ggctttgatatcgacggcgtggtgattaaggtcaactcactggaacagcaggagcagctt
ggctttgtcgcgcgtgccccgcgctgggcggtagcgtttaaattcccggcgcaggagcag
atgacctttgtgcgtgacgtcgagtttcaggttgggcgtactggcgcgattacgcctgtt
gcgcgtctggaacctgtccatgttgctggcgtgctggtgagtaacgcaaccttacacaat
gcggatgaaatcgaacgtcttggtttacgcattggcgataaagtggtgattcgccgcgct
ggcgacgtgatcccgcaggtggttaacgtcgtgctttctgaacgcccggaagatacccgt
gaggttgtattcccgacgcattgtccggtatgtggttctgacgttgagcgtgtggaaggt
gaagcggttgcccgctgtaccggtggcctgatttgcggtgcgcagcgtaaagagtcgctg
aaacactttgtttcccgccgtgcgatggatgttgacggaatgggcgacaaaatcatcgat
cagctggttgaaaaagaatatgtccatactccggcagatctgttcaaactcaccgcaggc
aaactgaccggactggagcgtatggggccaaaatcggcacaaaacgtggttaacgcgctg
gaaaaagcgaaagaaaccacctttgctcgcttcctctatgcacttggcatccgtgaagtc
ggcgaggccaccgcagcaggtctggcggcatatttcggcacgctggaagcgctggaagcc
gcttcgattgaagagctgcaaaaggtgcctgatgttggcattgtcgttgcatcccacgtt
cacaacttctttgccgaagaaagcaaccgcaatgtcatcagcgagctgttggcggaaggt
gttcactggcctgcgccgatcgttatcaacgcggaagagattgacagcccgtttgctggt
aaaaccgtggtgcttacgggcagcttaagccagatgtcgcgtgatgacgctaaagctcga
ctggttgaactgggcgcgaaagtcgcgggcagcgtgtcgaagaaaaccgatctggtgatt
gccggagaagcggcaggttctaaactggcgaaagcgcaggaactgggcattgaagtcatc
gacgaagcggaaatgctgcgtttgctgggtagctga

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