Etheostoma cragini (Arkansas darter): 117953315
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Entry
117953315 CDS
T07493
Symbol
hsd3b1
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
ecra
Etheostoma cragini (Arkansas darter)
Pathway
ecra00140
Steroid hormone biosynthesis
ecra01100
Metabolic pathways
Module
ecra_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
ecra_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
ecra_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ecra00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
117953315 (hsd3b1)
Enzymes [BR:
ecra01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
117953315 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
117953315 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
adh_short
NmrA
KR
Ldh_1_N
Motif
Other DBs
NCBI-GeneID:
117953315
NCBI-ProteinID:
XP_034742104
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Position
11:6778862..6782130
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AA seq
374 aa
AA seq
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MSLRGEVCVVTGAGGFLGKRLVMLLLEEEKMAEIRLLDKQIQPQLLDSLEDCKGNTKLSV
FEGDIRDGDFLRKSCRGASIVFHIAAIIDVNGSVEDSELYSVNVKGTQLLLEACIQENVV
SFIYTSTIEVMGPNSSGEPIINGSEDTVYNCSLKFAYSKTKKEAEQRTLQAHSEVLNNGG
RLATCALRPMYIYGEGCRFLLGHMGNGIRNKGVLFRMSQPEARVNPVYVGNVAIAHLQAA
RSLKDPQKRNVIGGKFYLISDDTPLQSYSDLNHVLMSPLGFNIQEKLMYPLPLLYMVCFL
MEMLCMMVRPFVRIVPPLNRQRVTLLNTPFSFSYEKAKRDLGYVPKYTWEEARKGTIEWL
ASELPKERERIIAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgagaggtgaagtgtgtgtggtgacaggagccggtgggttcctgggaaagagg
ctggtgatgctgctgctggaggaagagaaaatggctgagattcgactgctggacaaacaa
atacagccacaacttctagactctctggaggactgtaaaggcaacacaaagttgagtgtg
tttgaaggggacatcagagacggggatttcctgagaaaaagctgcagaggtgcatcaatc
gttttccacatcgcagccatcattgacgtgaatggctcagtggaggacagtgagctgtac
agtgtcaatgtcaaaggaacgcagctgctcctggaggcttgtattcaagagaacgtggtg
tccttcatctacaccagtaccatcgaggtgatgggaccaaactctagcggtgaacccata
atcaacggcagcgaggacacagtttacaactgttctctgaagtttgcctacagcaagacc
aaaaaggaggctgagcagagaaccctgcaggcccacagcgaggtgctcaataatggaggc
cggctggccacctgcgccctcagacctatgtacatctacggggagggctgccgcttcctg
ctgggccacatgggcaacgggatacgaaacaagggcgttttgtttcgtatgtctcaaccg
gaggcccgagtgaatcccgtgtatgtcggcaacgtggctatagcccacctccaagcagcc
cgcagtctcaaggatccacaaaaaagaaatgttatcggaggaaagttttacctaatttct
gatgacacgccacttcaaagttattcggacttaaaccacgtcctgatgtcccctctgggc
ttcaacattcaagagaagcttatgtacccgctccccctcctctacatggtctgcttctta
atggagatgctgtgcatgatggtgcgaccttttgtacgcatcgtcccgcccctgaaccgg
cagcgcgtcaccttgttgaacacgccattcagcttctcgtatgagaaggctaagagggat
ctgggatacgtccccaaatacacctgggaggaagcacgcaaaggcaccattgaatggctc
gcgtcagagctgccgaaggagagggaaagaataattgctaaataa
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