Escherichia coli O157 H7 Sakai (EHEC): ECs_3463
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Entry
ECs_3463 CDS
T00048
Symbol
tyrA
Name
(RefSeq) chorismate mutase-T and prephenate dehydrogenase
KO
K14187
chorismate mutase / prephenate dehydrogenase [EC:
5.4.99.5
1.3.1.12
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00400
Phenylalanine, tyrosine and tryptophan biosynthesis
ecs00401
Novobiocin biosynthesis
ecs01100
Metabolic pathways
ecs01110
Biosynthesis of secondary metabolites
ecs01230
Biosynthesis of amino acids
Module
ecs_M00024
Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
ecs_M00025
Tyrosine biosynthesis, chorismate => HPP => tyrosine
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09105 Amino acid metabolism
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
ECs_3463 (tyrA)
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
ECs_3463 (tyrA)
Enzymes [BR:
ecs01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.12 prephenate dehydrogenase
ECs_3463 (tyrA)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.5 chorismate mutase
ECs_3463 (tyrA)
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Gene cluster
GFIT
Motif
Pfam:
CM_2
PDH_C
PDH_N
F420_oxidored
Motif
Other DBs
NCBI-GeneID:
914857
NCBI-ProteinID:
NP_311490
UniProt:
Q8X9E3
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All DBs
Position
complement(3459200..3460321)
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AA seq
373 aa
AA seq
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MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAE
AEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPALRPVVIVGGGGQMGRLFEKMLTL
SGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNG
PLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRI
SAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDP
QLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSE
SRVLLRQANDNRQ
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggttgctgaattgaccgcattacgcgatcaaattgatgaagtcgataaagcgctgctg
aatttattagcgaagcgtctggaactggttgctgaagtgggcgaggtgaaaagccgcttt
ggactgcctatttatgttccggagcgagaggcatctatgttggcctcgcgtcgtgcagag
gcggaagctctgggtgtaccgccagatctgattgaggatgttttgcgtcgggtgatgcgt
gaatcttactccagtgaaaacgacaaaggatttaaaacgctttgtcctgcgttacgcccg
gtagttatcgttggcggcggcggtcagatgggacgtctgttcgagaagatgctgacactc
tcgggttatcaggtgcggattctggagcaacatgactgggatcgagcggctgatattgtt
gccgatgccggaatggtgattgttagtgtgccaatccacgttactgagcaagttattggc
aaattaccgcctttaccgaaagattgtattctggttgatctggcatcagtgaaaaatgga
ccattacaggccatgctggcggcgcacgatggcccggtactggggttacacccaatgttc
ggtccggacagcggtagcctggcaaagcaagttgtggtctggtgtgatggacgtaaaccg
gaagcataccaatggtttctggagcaaattcaggtctggggcgctcggttgcatcgtatt
agcgccgtcgagcacgatcagaatatggcgtttattcaggcactgcgccactttgctact
tttgcttacgggctgcacctggcagaagaaaatgttcagcttgagcaacttctggcgctc
tcttcgccgatttaccgccttgagctggcgatggtcgggcgactgttcgctcaggatccg
cagctttatgccgacattattatgtcgtcagagcgtaatctggcgttaatcaaacgttac
tataagcgtttcggcgaggcgattgagttgctggagcagggcgataagcaggcgtttatt
gacagtttccgcaaggtggagcactggttcggcgattacgcacagcgttttcagagtgaa
agccgcgtgttattgcgtcaggcgaatgacaatcgccagtaa
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