Escherichia coli O7 K1 IAI39 (ExPEC): ECIAI39_0114
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Entry
ECIAI39_0114 CDS
T00829
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ect
Escherichia coli O7:K1 IAI39 (ExPEC)
Pathway
ect00010
Glycolysis / Gluconeogenesis
ect00020
Citrate cycle (TCA cycle)
ect00620
Pyruvate metabolism
ect00785
Lipoic acid metabolism
ect01100
Metabolic pathways
ect01110
Biosynthesis of secondary metabolites
ect01120
Microbial metabolism in diverse environments
ect01200
Carbon metabolism
ect01210
2-Oxocarboxylic acid metabolism
Module
ect_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ect00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
ECIAI39_0114 (aceE)
00020 Citrate cycle (TCA cycle)
ECIAI39_0114 (aceE)
00620 Pyruvate metabolism
ECIAI39_0114 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ECIAI39_0114 (aceE)
Enzymes [BR:
ect01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
ECIAI39_0114 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
CAR16255
UniProt:
A0A0H3MD42
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All DBs
Position
133121..135784
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AA seq
887 aa
AA seq
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MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVNVAAGTGISNY
INTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDV
CFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQEQLDNFRQEVHGNGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKIYAAFKKAQETKGKATVILAHTIKGYGMGDAAEGKNIAHQVKKMNMDGVRH
IRDRFNVPVSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQ
DFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI
EGSKGKVQLLGSGSILRHVREAAEILAKEYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFNIDADKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttcccaaatgacgtggatccgatcgaaactcgcgactggctccaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgtgctcagtatctgatcgaccaactg
cttgctgaagcccgcaaaggcggtgtcaacgtagccgcaggcacaggtatcagcaactac
atcaacaccatccccgttgaagaacaaccggagtatccgggtaatctggaactggaacgc
cgtattcgttcagctatccgctggaacgccatcatgacggttctgcgtgcgtcgaaaaaa
gacctcgaactgggcggccacatggcgtccttccagtcttccgcaaccatttatgatgtg
tgctttaaccacttcttccgtgcacgcaacgagcaggatggcggcgacctggtttacttc
cagggccacatctccccgggcgtttacgcacgtgctttcctggaaggtcgtctgactcag
gagcagctggataacttccgtcaggaagttcacggcaatggcctctcttcctatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtatctatgggtctgggtccgatt
ggtgctatttaccaggctaagttcctgaaatatctggaacaccgaggcctgaaagatacc
tctaaacagaccgtttacgcattcctcggcgacggtgaaatggacgaaccggaatccaaa
ggtgcgatcaccatcgcaacccgtgaaaaactggataacctggtcttcgttatcaactgt
aacctgcaacgtcttgacggcccggtcaccggtaacggcaagatcatcaacgaactggaa
ggcatcttcgaaggtgctggctggaacgtgatcaaagtgatgtggggtagccgttgggat
gaactgctgcgtaaagataccagcggtaaactgatccagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatcgaaagatggtgcgtacgttcgtgaacacttcttcggt
aaatatcctgaaaccgcagcactggttgcagactggactgacgagcagatctgggcactg
aaccgtggcggtcacgatccgaagaaaatctacgctgcattcaagaaagcgcaggaaacc
aaaggcaaagcgacagtaatccttgctcataccattaaaggttacggcatgggcgacgcg
gctgaaggtaaaaacatcgcgcaccaggttaagaaaatgaacatggacggcgtgcgtcac
atccgcgaccgtttcaatgtgccggtgtctgatgccgatatcgaaaaactgccgtacatc
accttcccggaaggttctgaagagcatacctatctgcacgcgcagcgtcagaaactgcac
ggttatctgccaagccgtcagccgaacttcaccgagaagcttgagctgccgagcctgcaa
gacttcggcgcgctgctggaagagcagagcaaagagatctctaccactatcgctttcgtt
cgtgccctgaacgtaatgctgaagaacaagtcgatcaaagatcgtctggtaccgatcatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagattggtatttacagc
ccgaacggtcagcagtacaccccgcaggaccgcgagcaggttgcttactataaagaagac
gagaaaggtcagattctgcaggaagggatcaacgagctgggcgcaggttgttcctggctg
gcagcggcgacttcttacagcaccaacaatctgccgatgattccgttctacatctattac
tcgatgttcggtttccagcgtatcggtgacttgtgctgggcggctggcgaccagcaagcg
cgtggcttcctgatcggcggtacttccggtcgtaccaccctgaacggtgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcttacgcttacgaagttgctgtcatcatgcatgacggtctggagcgtatgtacggt
gaaaaacaagagaacgtttactactacatcactacgctgaacgaaaactaccacatgccg
gcaatgccggaaggtgctgaggaaggtatccgtaaaggtatctacaaactcgaaaccatt
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtccgt
gaagcggcagagatcctggcgaaagagtacggcgtaggttctgacgtttatagcgtgacc
tccttcaccgaactggcgcgtgatggtcaggattgtgaacgctggaacatgctgcacccg
ctggaaactccgcgcgttccgtacatcgctcaggtgatgaacgacgctccggcagtggca
tctaccgactatatgaaactgttcgctgagcaggtccgtacttacgtaccggctgacgac
taccgcgtactgggtactgatggcttcggtcgttccgacagccgtgagaacctgcgtcac
cacttcgaagttgatgcttcttatgtcgtggttgcggcgctgggcgaactggctaaacgt
ggcgaaatcgataagaaagtggttgctgacgcaatcgccaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa
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