KEGG   Escherichia coli O139 H28 E24377A (ETEC): EcE24377A_0052
Entry
EcE24377A_0052    CDS       T00590                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ecw  Escherichia coli O139:H28 E24377A (ETEC)
Pathway
ecw00670  One carbon pool by folate
ecw00790  Folate biosynthesis
ecw01100  Metabolic pathways
ecw01240  Biosynthesis of cofactors
ecw04981  Folate transport and metabolism
Module
ecw_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecw00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    EcE24377A_0052 (folA)
   00670 One carbon pool by folate
    EcE24377A_0052 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    EcE24377A_0052 (folA)
Enzymes [BR:ecw01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     EcE24377A_0052 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ABV20494
UniProt: A7ZHE1
LinkDB
Position
53020..53499
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPMIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccatg
attatgggccgccatacctgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gagcagttcctgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgacgccgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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