Enterococcus faecalis V583: EF3089
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Entry
EF3089 CDS
T00123
Name
(GenBank) glutamate--cysteine ligase, putative/amino acid ligase, putative
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
efa
Enterococcus faecalis V583
Pathway
efa00270
Cysteine and methionine metabolism
efa00480
Glutathione metabolism
efa01100
Metabolic pathways
efa01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
efa00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EF3089
09106 Metabolism of other amino acids
00480 Glutathione metabolism
EF3089
Enzymes [BR:
efa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
EF3089
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
RimK
GARS_A
ATPgrasp_ST
Dala_Dala_lig_C
Motif
Other DBs
NCBI-ProteinID:
AAO82770
UniProt:
Q82ZG8
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Position
complement(2962683..2964953)
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AA seq
756 aa
AA seq
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MNYRELMQKKNVRPYVLMARFGLEKENQRSTREGLLATTEHPTVFGNRSYHPYIQTDFSE
TQLELITPVANSGTEMLRFLDAIHDVARRSIPEDEMLWPLSMPPQLPTKDEEIKIAKLDQ
YDAVLYRRYLAKEYGKRKQMVSGIHFNFEYDQALIQQLYDEQSEVTDCKQFKTKVYMKVA
RNFLRYRWLITYLFGASPVSEDRYFRVYDDQPQEPVRSIRNSTYGYRNHDNVKVSYASLE
RYLEDIHRMVENGLLSEEKEFYAPVRLRGGKQMSDLPKTGIRYIELRNLDLNPFSRLGIV
EDTVDFLHYFMLYLLWTDEKEEADEWVKTGDIFNEQVALGHPHETIKLIAEGDRIFSEMI
DMLDALGIRKGKEVVGKYYQQLRNPQDTVSGKMWTIIQENSNSELGNIFGNQYQSMAFER
PYQLAGFREMELSTQIFLFDAIQKGLEIEILDEQEQFLKLQHGEHIEYVKNANMTSKDNY
VVPLIMENKTVTKKILSAAGFHVPGGEEFSSFIEAQEAHLRYANKAFVVKPKSTNYGLGI
TIFKEGASLEDFTEALRIAFKEDTAVLIEEFLPGTEYRFFVLDNDVKAIMLRVPANVTGD
GKHTVEELVAAKNSDPLRGTNHRAPLELIQLNDLEKLMLKEQGLTIYSVPEKEQIVYLRE
NSNVSTGGDSIDMTDVIDDSYKQIAIEAVAALGAKICGIDLIIPDKDVKGTRDSLTYGII
EANFNPAMHMHVYPYAGQGRRLTMDVLKLLYPEVVQ
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
atgaattatagagaattaatgcaaaagaaaaatgttcgtccttacgtattgatggctcgt
tttggtttagaaaaagaaaaccaacgtagtacacgagaagggcttttagcgacaactgag
catcccacggtttttggtaaccgttcttatcatccatatattcaaacagattttagtgaa
acacaattagaactaatcacgcctgtagcaaatagcggcacagaaatgcttcgtttttta
gatgccattcacgatgtggctcgtcgttcgattccagaagatgaaatgctgtggccatta
agtatgccgccacaattaccaacaaaagatgaagagattaaaattgctaaattagatcaa
tatgatgcggtgttatatcgtcgttatttggcaaaagagtatggcaaacgaaaacaaatg
gtcagcggaattcattttaattttgaatatgaccaagccctgattcagcaattatatgat
gaacaatccgaagtgacagattgtaaacaatttaaaacgaaagtgtacatgaaagttgcc
cgtaactttttacgttatcgctggttaattacgtatctttttggggcttcaccagttagt
gaagaccgctactttagggtctacgacgaccaaccgcaagaacctgttcgcagtattcgg
aatagtacgtatggctacagaaatcatgacaatgtgaaagtatcgtatgcctcattggaa
cgctatttagaagatattcatcgcatggtggaaaatggtttactttctgaagaaaaagaa
ttttatgcgcctgtgcgcttacgtggcgggaaacaaatgtctgatctgcctaaaacaggt
attcgctatatcgagttgcgtaatttagacttaaatcctttttcacgtttaggcattgtg
gaagatactgtggatttcttacattatttcatgttgtatttattgtggacagatgaaaaa
gaagaagcggatgaatgggtgaaaactggggatatttttaatgaacaagtggctcttggt
catcctcatgaaacgattaagttaattgcagaaggcgatcggattttttcagaaatgatt
gatatgttagatgctctaggcattcgcaaaggcaaagaagttgtcggtaagtattatcaa
caactgcggaatccacaagacaccgtttctggcaaaatgtggacgattattcaagaaaac
tccaacagtgaactgggaaatatttttggaaaccaatatcaaagtatggcctttgaacgc
ccttatcaattagctggtttccgtgagatggaattatccacacaaattttcttatttgat
gcgattcaaaaaggtttggaaatcgaaattttagatgaacaagaacaatttttgaaactg
caacatggcgagcacattgaatacgtcaaaaatgccaacatgactagcaaagataactac
gtggtaccattgattatggaaaacaaaaccgtgacaaagaaaattttgtctgcagcaggt
ttccatgtgcctggcggtgaagaattttcatcttttattgaggcacaagaagcacattta
cgctacgccaataaagcgtttgtcgtgaaaccaaaatcaacgaattacggtttaggaatt
acgatttttaaagaaggagcttcgttggaagactttacggaagcgttacggattgctttt
aaagaggacacagcggttttaattgaagaatttttacctggaacagaatatcggttcttt
gtgttagataatgatgtaaaagccatcatgttgcgcgtgccagccaatgttaccggagat
ggcaaacacactgtagaagaattggtggccgctaaaaatagtgatccattgcgggggacc
aatcaccgtgcaccactagagttaatccagttaaatgatttagaaaaactaatgttgaaa
gaacaaggtttaactatctattctgtgccagaaaaagagcaaatcgtgtacttgcgagaa
aattctaatgttagcacgggcggggattcgattgatatgaccgatgtcattgatgatagt
tataaacaaatcgccattgaggccgtagctgctttaggagccaaaatttgtggcattgat
ttaatcattcctgacaaagacgtaaaaggcacacgtgatagcttaacgtacgggattatc
gaagcgaactttaatccagccatgcacatgcatgtgtatccatacgctggacagggtaga
cgcttgacaatggacgttttaaaacttttatacccagaagtggttcaataa
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