KEGG   Enterococcus faecium Aus0004: EFAU004_00066
Entry
EFAU004_00066     CDS       T01772                                 
Symbol
dhfr_2
Name
(GenBank) dihydrofolate reductase
  KO
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
efc  Enterococcus faecium Aus0004
Pathway
efc00670  One carbon pool by folate
efc00790  Folate biosynthesis
efc01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:efc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    EFAU004_00066 (dhfr_2)
   00670 One carbon pool by folate
    EFAU004_00066 (dhfr_2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:efc01504]
    EFAU004_00066 (dhfr_2)
Enzymes [BR:efc01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     EFAU004_00066 (dhfr_2)
Antimicrobial resistance genes [BR:efc01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    EFAU004_00066 (dhfr_2)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AFC62152
LinkDB
Position
complement(68722..69219)
AA seq 165 aa
MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILGRKNLESIGRALPDRRN
IILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIYNLFFPYVEKMYITKIHHE
FEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYERKNLLS
NT seq 498 nt   +upstreamnt  +downstreamnt
atgaaagtttctttgattgctgcgatggataagaatagagtgattggcaaagagaatgac
attccttggaggattcccaaggactgggaatatgttaaaaatactacaaagggacatccg
ataatattaggtaggaagaaccttgaatcaatcggaagagccttacctgacagaagaaat
attattctgacgagagataaggggtttacctttaatggttgtgaaattgttcattcaata
gaagatgtttttgagttatgtaaaaacgaagaagaaatttttattttcggaggagaacag
atttataatttgtttttcccttatgttgagaaaatgtacatcacaaaaatacatcatgaa
ttcgaaggagatactttttttccagaagtgaattatgaggaatggaatgaggtatttgcc
caaaaagggataaagaatgataaaaatccgtataactactattttcatgtatatgaaaga
aaaaacttattgagttaa

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