Enterococcus faecalis OG1RF: OG1RF_12228
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Entry
OG1RF_12228 CDS
T01882
Symbol
folC
Name
(GenBank) tetrahydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
efi
Enterococcus faecalis OG1RF
Pathway
efi00790
Folate biosynthesis
efi01100
Metabolic pathways
efi01240
Biosynthesis of cofactors
Module
efi_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
efi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
OG1RF_12228 (folC)
Enzymes [BR:
efi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
OG1RF_12228 (folC)
6.3.2.17 tetrahydrofolate synthase
OG1RF_12228 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
CbiX
Ribosomal_60s
Motif
Other DBs
NCBI-ProteinID:
AEA94915
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Position
complement(2346821..2348143)
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AA seq
440 aa
AA seq
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MQLTIEEAIEWIHSRLPFGSRPGLDRINALLEKIDHPENKVPTIHIAGTNGKGSTVTYLR
CLLEEMGLKVGTFTSPYIESFNERIAINGQPISDEQLITYVEKYQPIIKELDQITEVAGI
TEFETLTGMALDYFVNEQVDIAVVEVGLGGLLDSTNVVKPLLTGITTIGKDHTEILGETI
AEIAYQKAGIIKEKVPVVTGNICADALAVIEKVAQEKQSPIFRFGKEYQVEYLHPDTQWG
EVFNFYGEMGKLTKIKVPLLGRHQVENAAVAIQLFDKYCQLQHLPFKERDITQGLAKAQW
PARMERLSDEPLIVLDGAHNDHAVKRLVENLRKEFPQHTIHILFSALATKDVDEMIQDLK
QVPNAHLYLTSFDYPKAIALTEMEKYEDDLTEIVSLWQFGLGEILEKMSTDDLLLVTGSL
YFVSQVRELLLTIGGNDEEI
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgcaattaacaatagaagaagccattgaatggattcatagccggttaccctttggttca
agacctggtttggatcggattaatgcgttattagaaaaaattgatcatccagaaaacaaa
gtgccaacgattcatatcgcaggaaccaatggtaaaggctcaaccgtgacatatttacgc
tgtctattagaagaaatgggcttgaaagtcggaacctttacctctccttatattgaatca
tttaatgaaagaattgcgataaatggtcaaccaatttcagacgaacaattgattacctat
gtggaaaagtatcaaccaatcattaaagaattagaccagatcactgaagtggctggaatt
acagaattcgaaacattgacaggaatggccttggactatttcgtgaatgaacaagtggat
atcgccgttgttgaagttggcttaggtggattacttgatagcaccaatgtcgtgaagcca
ttattgacgggaattacgacaattgggaaggatcacacagaaattttaggtgaaacaatt
gctgaaattgcctatcaaaaagcgggtattattaaagaaaaagtcccagtagtaacaggc
aatatttgtgctgatgcgctagcagtcattgaaaaagtcgcacaagaaaaacagagtcca
atttttcgttttggcaaagagtatcaagtggaatatctacatcctgatacacaatggggg
gaagtatttaatttctatggagaaatgggcaaactgacaaaaattaaagttcccttgttg
gggcgtcaccaagtagaaaacgcggcggtagctattcaattatttgacaagtattgccaa
ctacaacatttgccgtttaaagaacgagacattactcaagggttagctaaagcgcaatgg
ccagctcgaatggaacgtcttagtgatgaaccgttgattgttttagatggtgcccacaat
gatcatgcagtaaaacgcttagttgaaaacttgcgcaaagagtttccacaacacacgatt
catattttattttcagctttagcaactaaagatgtagatgagatgattcaggacttaaag
caagtaccgaatgcgcatctttacttaactagctttgattaccctaaagctattgcactt
acagaaatggaaaaatatgaagacgatttaacagaaattgtgtctttatggcaatttggc
ttaggcgaaattttagaaaaaatgtcgacagatgatttattattagtaacaggttcatta
tattttgtttctcaagtaagagaattacttttaactataggaggaaatgatgaagaaatt
tga
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