Epinephelus fuscoguttatus (brown-marbled grouper): 125900207
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Entry
125900207 CDS
T08419
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
efo
Epinephelus fuscoguttatus (brown-marbled grouper)
Pathway
efo00140
Steroid hormone biosynthesis
efo01100
Metabolic pathways
Module
efo_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
efo_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
efo_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
efo00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
125900207 (hsd3b1)
Enzymes [BR:
efo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
125900207 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
125900207 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
adh_short
Motif
Other DBs
NCBI-GeneID:
125900207
NCBI-ProteinID:
XP_049451069
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Position
LG13:34953800..34958101
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AA seq
374 aa
AA seq
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MSLRGEVCVVTGAGGFLGKRLVRLLLEEERMAEIRLLDKHIQLQLLQSLEDCRGDTKLTV
FEGDIRDADFLRKSCRGASIVFHIASIIDIFDAVEYSEIYGVNVKGTQLLLEACIQENVV
SFIYTSTIEVMGPNSKREPIIKGSEDTVYDCTLKFAYSKTKKEAEQRTLQAHSEVLQNGG
RLATCALRPMYIYGEGCRFLLGHMGDGIQNKDVLYRMSLPEAKVNPVYVGNVAVAHLQAA
RSLSDPQKRNVIGGKVYFIADDTPPVSYSDFNHVVMSPLGFSIQEKLMYPLWLFYTFCFL
MEMVCMVLQPMVRIVPPLNRQLVTMLNTPFSFSYQKAKRDLGYTPRYTWEEARRRTTEWL
ASELPKERERIRAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgagaggtgaagtgtgtgtggtgacgggagccggtggattcctgggaaagagg
ctggtgaggctgctgctggaggaggagagaatggctgagattcgactgctggacaaacac
atacagctgcagcttttacagagtctggaggactgtagaggcgacacaaagctgaccgtt
ttcgagggcgacatcagagacgctgatttcctgagaaaaagctgtcgaggtgcatcgatc
gtcttccacatcgcatccatcattgacatttttgacgcggtggagtacagcgagatatac
ggggtcaatgtcaaaggaacacagctgcttctggaggcgtgtattcaagagaacgtggtg
tccttcatctacaccagcaccatcgaggtgatgggaccgaactctaaacgtgaacccata
atcaaaggcagcgaggacacggtttacgactgcactctgaagttcgcctacagcaagacc
aaaaaagaggctgagcagagaaccctgcaggcccacagcgaggtgctccaaaatggaggc
cgcttggccacctgcgccctcagacccatgtacatctatggtgaggggtgccgcttcctg
ctgggccacatgggcgacgggatacagaacaaggatgttttatatcgcatgtctctacca
gaggccaaagtgaatcctgtgtatgtgggcaacgtggcagtggctcacctccaagcagcc
cgcagcctcagtgatccacaaaaaagaaacgtcatcggaggaaaggtttacttcatcgct
gacgacacgcctcccgtgagttattcagacttcaaccacgttgtgatgtcacctctgggc
ttcagcattcaagagaagctcatgtacccgctgtggctcttctacacgttctgcttctta
atggagatggtctgcatggtgctccaacctatggtacgcatcgtcccgccactgaaccgg
cagctcgtcaccatgttgaacacgccgttcagcttctcctatcagaaggcgaagagggat
ctggggtacacccccagatacacctgggaggaagctcgcaggcgcaccactgaatggctc
gcgtcagagctgccaaaggagcgtgagagaataagagctaaataa
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