Eptesicus fuscus (big brown bat): 103286902 Help Entry 103286902         CDS       T09083                                  Symbol ACACB Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism efus  Eptesicus fuscus (big brown bat) Pathway efus00061   Fatty acid biosynthesis efus00620   Pyruvate metabolism efus00640   Propanoate metabolism efus01100   Metabolic pathways efus04152   AMPK signaling pathway efus04910   Insulin signaling pathway efus04920   Adipocytokine signaling pathway efus04922   Glucagon signaling pathway efus04931   Insulin resistance efus04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:efus00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     103286902 (ACACB)    00640 Propanoate metabolism     103286902 (ACACB)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     103286902 (ACACB)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     103286902 (ACACB)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     103286902 (ACACB)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103286902 (ACACB)    04922 Glucagon signaling pathway     103286902 (ACACB)    04920 Adipocytokine signaling pathway     103286902 (ACACB)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     103286902 (ACACB)    04931 Insulin resistance     103286902 (ACACB) Enzymes [BR:efus01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      103286902 (ACACB)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      103286902 (ACACB)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      103286902 (ACACB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 Biotin_lipoyl_2 Motif Other DBs NCBI-GeneID:  103286902 NCBI-ProteinID:  XP_054568437 LinkDB All DBs Position 23:complement(21424873..21499817) Genome browser AA seq 2452 aa AA seqDB search MTLLLCLCCLIFSCLTFSWLKIWGKMTDSKPVTKNKSEASFIPSQDPFPAPNSSEEPPQK NGDSSSLPKTPNQTEPASQKGPKDADRQRTSRPPRHRNPSKSPLASRDASPANGTRTPGP EAPDTNGLSSPARPQARARTLSKEDQKQARIKRQLMTNFILGSFDDNSSDEDPGTGSGRE SSRRGSRAGLGALTLEAARAAGDSETLVPAMRPSMSGLHLVKRGREHKRVDVHRDFTVAS PAEFVMRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKA NAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCK DEIAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLTVEWAEDGLQEGKRISVPE DVYSQGCVKDIEEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPG SPVFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPVVFEF MEQCAVRLAKTVGYVSAGTVEYLYSEDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQ IAMGVPLHRLKDIRLLYGESPWGVTPIAFETPPNPPLARGHVIAARITSENPDEGFKPSS GTVQELNFRSSRNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAVSNMVVALKELSI RGDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVADAM FRTCMTDFLHSLERGQVLPADFLLNTVDVELIYGGIKYILKVARQSLTMFVLIMNGGHIE IDAHRLNDGGLLLSYDGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLT QYTVEDGGHVEAGDSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVARLELDDP SKVHPAKPFTGELPAQQTLPIMGEKLNQVFHSVLENLTNVMSGYCLPEPIFSIKLKEWVQ KLMMTLRHPSLPLLELQDIMTNVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIAN ILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLKRYLQVEHHFQQ AHYDKCVINLREQLKPDMAQVLHCIFSHAQVAKKNQLVIMLIDELCSPDPSLSEELTSIL SELTQLSKTEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAVDRYGHQFCPENLKKL ILSETTIFDVLPTFFYHVNKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFM LPSSHPNRIAVPVSITNPDLLRHSTELYMDSGFSPLCQRMGAMVAFRRFEEFTRNFDDVI SCFANVPRDAPLFSKAQTSVYCEEDCKNFREEPIHILNVAIQCAEHLEDEELVPILRTFV QSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMR NFDVTAVPCANHKMHLYLGAAKVKEGVEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGE RLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPYKIEEAVRSMVMRYGSRLWKLR VLQAEVKINIRETAAGSAIPIRLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNKQGA QHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPDKYPKDMLTYT ELVLDPQGQLVEMNRLPGGNEVGMVAFKMHLKTREYPEGRDLVLISNDITFRIGSFGVGE DLLYLRASQLARAEGIPQIYLAANSGARIGLAEEIKHMFQVAWVDPEDPLKGFKYLYLTP QEYTRISSLNSVHCKHVEEEGESRYVITDIIGKDDGLGVENLRGSGMIAGECSLAYDEIV TISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIM HNNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIISPTDPIDREIEFSPSRAPYDPR WMLAGRSHPTLKGSWQSGFFDQGSFKEILAPWAQTVVTGRARLGGIPVGVIAVETRTVEV VVPADPANLDSEAKITQQAGQVWFPDSAYKTAQVIKDFNQEKLPLMIFANWRGFSGGMKD MYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADKESRG GVLEPEGTVEIKFRKKDLIKAMRRIDPTYKKLVEQLGVSDLSDKERKDLEGRLKAREELL LPIYHQVAVQFADLHDTPGRMLEKGVISDVLEWRTSRTFLYWRLRRLLLEDQVKKEILQV SSELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVQWLEQHWQVGDGLRSTIGENIKYL KRDSVLKTIRGLVQENPEVAVDCIMYMSEHISPAQRAQVAHLLSTMDSPAST NT seq 7359 nt NT seq  +upstreamnt  +downstreamnt atgaccttgctgctttgcctgtgttgtctgattttctcctgcctgaccttttcctggtta aagatctgggggaaaatgacagactccaagccagtcaccaagaataaatcggaggcgagc ttcatcccaagccaggacccctttccagcccccaacagctccgaggagccaccgcagaaa aatggagacagcagctctttgccaaagactcctaaccagacggagccggcctcccagaaa ggccccaaagatgccgatcggcaaagaacctccaggccaccccgacacaggaatccctcc aaaagcccccttgcctcccgggatgcctccccagccaatgggacaaggaccccaggcccg gaggcccccgacaccaatggcctgtcctcgccggccaggccgcaggcccgagccagaacc ctctccaaagaggaccagaagcaggcgcgcatcaagaggcagctgatgaccaacttcatc ctgggctccttcgacgacaactcctctgacgaggacccggggactggctccggccgagaa tcttcccgcaggggcagcagggccggcctgggggccctgaccctggaggctgctcgggct gcaggcgactctgagacccttgtccccgcgatgaggcccagcatgtctggactccacctg gtgaagaggggccgagaacacaagagggtggacgtgcacagagacttcaccgtggcttcg ccagccgagtttgtcatgcgctttgggggggaccgggtcattgagaaggtgctcatcgcc aacaacggcatcgccgccgtgaagtgcatgcgctccatccgcaggtgggcctacgagatg ttccgaaacgagcgggccatccggtttgtagtcatggtgactccagaggacctcaaggcc aacgcagagtatatcaagatggcagaccagtatgtccccgtcccgggggggcccaacaac aacaactacgccaacgtggagctgatcgtggacatcgccaagaggatccccgtgcaggcg gtgtgggctggctggggccatgcttccgaaaaccccaaacttccggagctcctgtgcaag gacgagattgctttcttaggccctcccagcgaggccatgtgggccctgggagacaagatc gcctccaccatcgtggcccagacgctgcaggttccaacactgccctggagcggaagcggc ctgacggtggagtgggcagaggatggcctgcaggaggggaagaggatcagcgtcccggaa gacgtgtacagccagggctgtgtgaaggacatagaggagggcttggaggcagcagaaaga attggtttcccgctgatgatcaaagcgtccgaaggcggcggagggaaagggatccggaag gcggagagtgccgaggacttccccatcctgttccgacaggtgcagagcgagatcccgggc tcccccgtcttcctcatgaagctggcccagcacgcccggcacctggaggtgcagatcctc gccgaccagtacggcaacgccgtgtccctgttcgggcgggactgctccatccagcggcgc catcagaagatcatcgaggaggcgcccgccaccatcgccaccccagtcgtgttcgagttc atggagcagtgtgccgtccgcctggccaagaccgtgggctacgtgagcgcggggacggtc gaatacctgtacagcgaggacggcagcttccacttcctggagctgaacccccggctgcag gtggaacatccctgcacggaaatgatcgccgacgtcaacctgccggccgcccagctgcag atcgccatgggcgtgccgctgcaccggctgaaagacatccgcctgctgtatggagagtca ccgtggggggtgacgcccatcgctttcgaaacccctcccaacccgcccctcgcccgtggc cacgtcattgcagccagaatcaccagcgaaaaccctgatgaggggttcaagccgagctcc gggacagtccaggagctgaatttccgcagcagcaggaacgtgtggggctatttcagcgtg gcggccaccgggggcttgcacgagtttgctgactcccagttcgggcactgcttctcctgg ggagagaaccgggaagaggccgtctcgaacatggtggtggctttgaaggaactgtccatc cggggcgacttcaggaccaccgtggagtacctcatcaacctcctggagaccgagagcttc cagaacaacgacatcgacaccgggtggctggatcacctcatcgccgagaaagtgcaggcc gagaagccggatatcatgctcggggtggtgtgtggcgccttgaacgtggccgacgcgatg ttcagaacctgcatgacggatttcctacactcgctggagaggggccaggtcctacctgcg gattttctgctgaacaccgtggatgtggaattgatttacggaggcattaagtacattctc aaggtggcccggcagtcgctgaccatgttcgtcctcatcatgaacggtggtcacatcgag atcgacgcccaccggctgaacgacggcgggctcctgctgtcctacgacgggaacagctac acgacctacatgaaggaggaggtggacagttaccggatcaccatcggcaacaagacgtgc gtgtttgagaaggagaacgaccccacggtcctgcggtccccctcggccgggaagctgacg cagtacacggtggaggacggcggccacgtggaggccggggacagctacgccgagatggag gtgatgaagatgatcatgaccctgaacgtgcaggaaagtggccgggtgaagtacatcaag cgcccgggggccgtgctggaagcgggctgcgtggtggccaggctggagctcgatgaccct tccaaggtgcacccggccaagccgttcacaggggagctccccgcccagcagacgctgccc atcatgggggagaagctgaaccaggtcttccacagcgtcctggagaacctcaccaacgtc atgagcggctactgcctgccggagcccatcttcagcataaagctgaaggagtgggtgcag aagctcatgatgaccctgcgacacccgtcgctgccgctgctggagctgcaggatatcatg accaacgtgtcgggccgcatccccgcccccgtggagaagtcggtccgcagggtgatggcc cagtatgccagcaacatcacctccgtgctctgccagttccccagccagcagatagccaac atcctggactgccacgcggccaccctgcagcggaaggccgaccgggaggtgttcttcatg aacacgcagagcatcgtgcagttggtccagcgataccgcagcgggacccgcggctacatg aaggcggtggtgttggacctcctgaaacgatacttacaagtcgagcaccacttccaacaa gcccactacgacaagtgcgtgatcaacctccgggagcagctgaagccggacatggcgcag gtgttgcactgcatcttctcgcacgcgcaggtggccaagaagaaccagctggtgatcatg ctgattgatgaactctgtagcccagacccttccctgtcggaggagctgacctccatcctc agcgagctcacgcagctgagcaagaccgagcactgcaaagtggccctcagagccagacag gtcctgatcgcctcccatctcccctcctatgagctgaggcacaaccaggtggagtccatt ttcctgtctgccgtcgacaggtacggccaccagttctgcccggaaaacctcaagaaatta atactctcggagacgaccatatttgacgtcctgcccacgttcttctatcacgtcaacaag gtggtttgcatggcgtccttggaggtgtatgtgcggaggggctacattgcctacgagcta aacagcctgcagcaccggcagctcccggacggcacctgcgtggtggaattccagttcatg ctgccctcctcccaccccaacaggatagccgtgcccgtcagcatcaccaatcccgacctg ctgagacacagcaccgagctctacatggacagcggcttctcccccctgtgtcagcggatg ggtgccatggttgccttcaggagattcgaggagttcaccaggaacttcgatgatgtcatc tcctgcttcgccaacgtgccccgggacgcccccctcttcagcaaggcccaaacctccgtg tactgtgaggaggactgcaagaacttccgcgaagagcccatccacatcctgaacgtggcc atccagtgcgccgagcacctggaggacgaggagctggtgccgattttgcggaccttcgtg cagtccaagaaaaacatccttgtggactacgggctccgaaggatcacgttcctgatcgcc caggagaaagaatttcccaagtttttcaccttcagagcaagagacgagtttgcagaagat cgcatttaccgtcacctggagcccgccctggccttccagctggagctcagccggatgcgc aatttcgacgtgacggccgtgccctgcgccaaccacaagatgcacctttacctgggcgct gccaaggtgaaggagggcgtggaggtgaccgactacaggttcttcatccgcgccatcatc cggcactcggacctgattacgaaggaggcctccttcgagtacctgcagaatgagggcgag cggctgctcctggaggccatggacgagctggaggtggccttcaacaacaccagcgtgcgc accgactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggacccctacaag atcgaggaggccgtgcgctccatggtcatgcgctacggcagccggctgtggaagctccgc gtgctccaggccgaggtcaagatcaacatccgcgagaccgccgccggcagcgccatcccc atccgcctgttcatcaccaacgagtcaggctactacctggacatcagcctctacaaggaa gtcaccgaccccagatccggaaacatcctgtttcactcctttggcaacaaacaaggagcc cagcacgggatgctgatcaacacgccctacgtcaccaaggacctgcttcaggccaagcgg ttccaggcccagtccctgggaaccacctacgtgtacgacttcccagaaatgttcaggcag gctctctttaaactgtggggctccccagacaagtaccccaaagacatgctgacatacacg gagctggtgctggacccgcagggccagctggtggagatgaaccggcttcccggaggaaac gaggtgggcatggtggccttcaaaatgcatctgaagacccgggagtatccggaagggcgg gacctggtcctcatcagcaacgacatcaccttccgcatcggctccttcggcgtgggagag gacctcctgtacctgcgcgcgtcccagctggcccgggccgagggcatcccccagatctac ctcgcggccaacagcggggcccgcatcggcctcgcggaggagatcaagcacatgttccag gtggcgtgggtggaccccgaggaccccctcaagggatttaagtacctgtacctgaccccc caagagtacacccggatcagctccctgaactccgtccactgcaaacacgtcgaggaggaa ggagaatccaggtatgtcatcaccgacatcattgggaaggacgatggcctgggcgtggag aacctgagggggtcaggcatgatcgcaggggagtgctccctggcttatgacgagatcgtc accattagcatggtgacctgccgcgccctgggcatcggggcctacctggtgaggctgggc cagcgggtgatccaggtggaaaactcccacatcatcctgacaggagccagcgccctcaac aaggtcctgggcagagaggtctacacgtccaacaaccagctgggcggcgtgcagatcatg cataacaatggcgtctcccacatcaccgtgcccgacgacttcgagggcgtttacaccatc ctggagtggctgtcctacatgcccaaggataatcacagcccggtccccatcatcagtccc accgaccccattgacagagagattgagttttccccatcgagagccccctacgacccccgg tggatgcttgcaggaaggtctcacccaactctgaaggggtcctggcagagcggattcttc gaccagggcagcttcaaggaaatcctggcgccctgggcccagaccgtggtgacgggacga gcaaggctggggggcatccctgtcggagtgatcgccgtggagacgcggacggtggaggtg gtggtgcccgcagacccggccaacctggattccgaggccaagataacccagcaggcgggc caggtgtggttcccggactccgcctacaagacggcccaggtcatcaaggacttcaaccag gagaagttgcccctgatgatctttgccaactggaggggtttctccggtggcatgaaagat atgtacgaccaggtgctgaagttcggggcctacatcgtggacggcctccggcagtacaag cagcccatcctcatctacatcccgccctacgcggagctccggggcggctcctgggtggtc ctggactccaccatcaaccccctgtgcatagagatgtacgcagacaaagagagcaggggg ggtgttctggagccggagggaacagtggagattaagttccgaaagaaagacctgataaag gccatgaggaggatcgacccaacttacaagaagctcgtggagcagttaggagtgtctgat ctctccgacaaggagcgcaaggacctggagggccggctgaaggcccgggaggaactgctg ctgcccatctaccaccaggtggcggtgcagttcgccgacctccacgacacgccgggcagg atgctggagaagggtgtcatctccgacgtcctggagtggaggacctcgcgcaccttcctg tattggcgcctgcgccgcctgctgctggaggaccaggtgaagaaggagatcctgcaggtc agcagcgagctcagccacgtgcacatccagtccatgctgcgccgctggttcgtggagacg gagggcgccgtcaaggcctacctgtgggacaacaaccagatggtggtgcagtggctggag cagcactggcaggtgggcgacggcctgcgctccaccatcggcgagaacatcaagtacctg aagcgcgattctgtcctcaagaccatccgaggcctggtccaagagaaccccgaggtggct gtggactgcataatgtacatgagcgagcacatcagcccggcccagcgggcccaggtcgct cacctcctgtccaccatggacagcccggcctccacctga

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