KEGG   Eptesicus fuscus (big brown bat): 103290523
Entry
103290523         CDS       T09083                                 
Symbol
PDPK1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1 isoform X1
  KO
K06276  3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01524  Platinum drug resistance
efus03320  PPAR signaling pathway
efus04068  FoxO signaling pathway
efus04071  Sphingolipid signaling pathway
efus04140  Autophagy - animal
efus04150  mTOR signaling pathway
efus04151  PI3K-Akt signaling pathway
efus04152  AMPK signaling pathway
efus04210  Apoptosis
efus04360  Axon guidance
efus04510  Focal adhesion
efus04660  T cell receptor signaling pathway
efus04664  Fc epsilon RI signaling pathway
efus04722  Neurotrophin signaling pathway
efus04910  Insulin signaling pathway
efus04919  Thyroid hormone signaling pathway
efus04931  Insulin resistance
efus04960  Aldosterone-regulated sodium reabsorption
efus05145  Toxoplasmosis
efus05205  Proteoglycans in cancer
efus05208  Chemical carcinogenesis - reactive oxygen species
efus05213  Endometrial cancer
efus05215  Prostate cancer
efus05223  Non-small cell lung cancer
efus05231  Choline metabolism in cancer
efus05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    103290523 (PDPK1)
   04071 Sphingolipid signaling pathway
    103290523 (PDPK1)
   04151 PI3K-Akt signaling pathway
    103290523 (PDPK1)
   04152 AMPK signaling pathway
    103290523 (PDPK1)
   04150 mTOR signaling pathway
    103290523 (PDPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103290523 (PDPK1)
  09143 Cell growth and death
   04210 Apoptosis
    103290523 (PDPK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103290523 (PDPK1)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    103290523 (PDPK1)
   04664 Fc epsilon RI signaling pathway
    103290523 (PDPK1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103290523 (PDPK1)
   03320 PPAR signaling pathway
    103290523 (PDPK1)
   04919 Thyroid hormone signaling pathway
    103290523 (PDPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103290523 (PDPK1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    103290523 (PDPK1)
  09158 Development and regeneration
   04360 Axon guidance
    103290523 (PDPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103290523 (PDPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    103290523 (PDPK1)
   05231 Choline metabolism in cancer
    103290523 (PDPK1)
  09162 Cancer: specific types
   05215 Prostate cancer
    103290523 (PDPK1)
   05213 Endometrial cancer
    103290523 (PDPK1)
   05223 Non-small cell lung cancer
    103290523 (PDPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103290523 (PDPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103290523 (PDPK1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    103290523 (PDPK1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    103290523 (PDPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103290523 (PDPK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:efus04131]
    103290523 (PDPK1)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103290523 (PDPK1)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: AGC group
  PDK1 family
   103290523 (PDPK1)
Membrane trafficking [BR:efus04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    103290523 (PDPK1)
SSDB
Motif
Pfam: Pkinase PH_3 PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal ABC1 Haspin_kinase APH Kdo
Other DBs
NCBI-GeneID: 103290523
NCBI-ProteinID: XP_008144653
LinkDB
Position
4:complement(12241793..12323841)
AA seq 558 aa
MARTTSQLYDTIPIQSSVVLCSCPSPSMVRTQTDSGTAPVVPSGGSRQGPTMDSTAAESR
PSANSLQHAAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHI
IKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD
ETCTRFYTAEMVSALEYLHGRGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQAR
ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE
YDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHSFFESITWENLHHQTPPKL
TAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRAGSNIEQYIHD
LDTNSFELDLQFSEDEKRLLLEKQASGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLL
TEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCKK
IQEVWRHRYQSHPDTTVQ
NT seq 1677 nt   +upstreamnt  +downstreamnt
atggccaggaccaccagccagctgtatgacaccattcctattcagtccagcgtggtgtta
tgttcctgcccatccccatcaatggtgaggacccagactgattccggcacggcccctgtt
gttcccagcggtggtagcaggcagggccccaccatggacagcactgcggctgagtcccga
ccaagtgccaactcactgcaacatgctgcacagccaccaccacagcctcggaagaaacgg
ccagaagacttcaaatttgggaaaattcttggtgaaggatctttttcaacagttgttctg
gcccgagaactggcaacctcaagggaatatgctattaaaattctagagaaacgtcacatt
atcaaagagaacaaggtcccgtatgtaaccagagagagagacgtgatgtcgcgcctggat
caccccttctttgttaaactttacttcacgtttcaggatgatgaaaagctgtattttggc
cttagttatgccaaaaatggagaactacttaaatacattcgcaaaattggttcattcgat
gagacgtgcacccgattttacacagctgagatggtgtctgctctagagtacttgcatggc
aggggcatcattcacagggacctgaaaccagaaaacattttgttaaatgaagatatgcac
atccagatcacagattttggaacagcaaaagtattatccccagagagtaaacaagccagg
gccaactcgtttgtaggaacagcccaatatgtttctccagagctgctcacagagaaatcg
gcctgtaaaagttcagacctttgggctcttggatgtataatataccagcttgtggcagga
ctcccaccattccgagccggaaacgaatatcttatatttcagaagatcattaagttggaa
tatgactttcctgaaaaattctttcctaaggcaagagaccttgtggaaaaacttttggtt
ttagatgccacaaagcgattaggctgtgaagaaatggaaggatacggtcctctgaaagct
cattcattctttgagtccattacgtgggagaatttgcatcatcagacacctccgaaactc
accgcttacttaccagccatgtcggaagatgatgaagactgctatggaaactacgacaat
ctcctgagccagtttggctgcatgcaggtgtcatcgtcgtcatcctcccactccctgtct
gcctcggacacgggtctgccacagagggcgggcagcaacatcgagcagtatatccatgac
ctggacactaattcttttgaactggacttacagttttccgaagatgagaagaggttatta
ttggagaagcaggccagtggaaacccttggcaccagtttgtagaaaataatttaatacta
aaaatgggtccagtagataagcgaaagggtttatttgcacgacgacgacagttattactt
acagaagggccacacttatattatgtggatcctgtcaacaaagtcctgaaaggtgaaatt
ccgtggtcacaagaactccgaccagaggccaagaattttaaaaccttctttgtccacaca
ccaaacaggacgtattacctgatggacccgagcgggaatgctcacaaatggtgcaaaaag
attcaggaggtgtggaggcacagataccagagccacccagacaccaccgtgcagtga

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