KEGG   Eptesicus fuscus (big brown bat): 103291391
Entry
103291391         CDS       T09083                                 
Symbol
HTRA2
Name
(RefSeq) serine protease HTRA2, mitochondrial isoform X1
  KO
K08669  HtrA serine peptidase 2 [EC:3.4.21.108]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus04210  Apoptosis
efus04215  Apoptosis - multiple species
efus05012  Parkinson disease
efus05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:efus00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    103291391 (HTRA2)
   04215 Apoptosis - multiple species
    103291391 (HTRA2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    103291391 (HTRA2)
   05022 Pathways of neurodegeneration - multiple diseases
    103291391 (HTRA2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:efus01002]
    103291391 (HTRA2)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:efus03110]
    103291391 (HTRA2)
Enzymes [BR:efus01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.108  HtrA2 peptidase
     103291391 (HTRA2)
Peptidases and inhibitors [BR:efus01002]
 Serine peptidases
  Family S1: chymotrypsin family
   103291391 (HTRA2)
Chaperones and folding catalysts [BR:efus03110]
 Other chaperones and cochaperones
  DegP / HtrA
   103291391 (HTRA2)
SSDB
Motif
Pfam: Trypsin_2 Trypsin PDZ_6 PDZ_2 PDZ Peptidase_S46 GRASP55_65 PDZ_Tricorn
Other DBs
NCBI-GeneID: 103291391
NCBI-ProteinID: XP_008145626
LinkDB
Position
16:45479724..45483251
AA seq 456 aa
MAALRAWRGAGWSLRGWRALGGFRWGKAPLLTPDLRALLTSGTPRARVTYGTPSLRARFS
VGVPGPRTCLTSGTPDSRARLTAGAPDRQTREDPGTPGSPPRAWLAVALGAGGAVLLLLW
GGGRGPPAVFASVLGPPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPISNG
SGFVVAADGLIVTNAHVVADRRRVRVRLPSGDTYEATVTAVDPVADIATLRIQTKEPLPT
LPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSVQRPAKELGLPQNNVEYIQTDAAID
FGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGTSGSQRRYI
GVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQVVQ
NAEDIYEAVRTQSQLAVRIRRGPEKLTLYVTPEITE
NT seq 1371 nt   +upstreamnt  +downstreamnt
atggctgcactgagggcgtggcggggtgcaggctggagccttcggggatggcgggctttg
gggggatttcgctgggggaaggcgcccctgttgacccctgacctccgggcactgctgacg
tcaggaactcctcgggcccgagtgacttatgggacccccagtctccgggcccggttctct
gtgggggtccctggaccacgaacgtgtctgacgtcggggactccggattcccgagcacgg
ctgactgcgggggccccggatcgtcagacccgggaggacccagggacccctgggtcccct
ccgcgcgcgtggctggctgtggccctgggcgctgggggggcagtgctactgttgttgtgg
ggcggggggcggggtcccccggccgtctttgcctctgtccttggcccgccgcccacctct
ccccggagccaatacaacttcatcgctgacgtggtggagaagaccgcacctgcggtcgtt
tatatcgagatcctgggccgacaccccttttctggccgcgaagtccccatctcgaatggc
tcaggattcgtggtggccgcggacgggctcattgttaccaacgcccacgtggtggctgat
cggcgccgagttcgtgtgaggctgcctagcggcgacacatatgaagccacggtcacagct
gtggatccggtggcagacatcgccacgctgaggattcagaccaaggaacctctccccacg
ctgcccctgggacgctcagctgatgtcaggcaaggggagtttgttgttgccatgggaagc
ccctttgcactgcagaacacgatcacgtccggcatcgtcagctctgttcagcgtccagcc
aaagaactaggcctcccccaaaacaatgtggaatacatccagactgatgcagctattgat
tttggaaattctggaggtcccctggttaacctggatggggaggtgatcggagtgaatacc
atgaaggtcacagctggaatctcctttgccatcccttctgatcgccttcgagagtttctg
catcgtggggaaaagaagaattcctggtttggaaccagtgggtcccagcgccgctacatt
ggggtgatgatgttgaccctgactcccagcatccttgctgaactacagcttcgagaacca
agttttcctgatgtccagcatggtgtgctcatccataaagtcatcctggactcccctgca
caccgggctggtctgcggccaggtgatgtgatcttggccattggggagcaggtggtacaa
aatgctgaagatatttatgaagctgttcgaacccaatcccagctggcagttcggatccgg
cggggaccagaaaaactgactttatatgtgacccctgaaatcacagaatga

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