KEGG   Eptesicus fuscus (big brown bat): 103292479
Entry
103292479         CDS       T09083                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X2
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01522  Endocrine resistance
efus04110  Cell cycle
efus04115  p53 signaling pathway
efus04151  PI3K-Akt signaling pathway
efus04218  Cellular senescence
efus04530  Tight junction
efus04660  T cell receptor signaling pathway
efus04933  AGE-RAGE signaling pathway in diabetic complications
efus04934  Cushing syndrome
efus05160  Hepatitis C
efus05162  Measles
efus05163  Human cytomegalovirus infection
efus05164  Influenza A
efus05165  Human papillomavirus infection
efus05166  Human T-cell leukemia virus 1 infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05169  Epstein-Barr virus infection
efus05200  Pathways in cancer
efus05203  Viral carcinogenesis
efus05212  Pancreatic cancer
efus05214  Glioma
efus05218  Melanoma
efus05219  Bladder cancer
efus05220  Chronic myeloid leukemia
efus05222  Small cell lung cancer
efus05223  Non-small cell lung cancer
efus05224  Breast cancer
efus05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    103292479 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    103292479 (CDK4)
   04115 p53 signaling pathway
    103292479 (CDK4)
   04218 Cellular senescence
    103292479 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    103292479 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    103292479 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103292479 (CDK4)
   05203 Viral carcinogenesis
    103292479 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    103292479 (CDK4)
   05225 Hepatocellular carcinoma
    103292479 (CDK4)
   05214 Glioma
    103292479 (CDK4)
   05220 Chronic myeloid leukemia
    103292479 (CDK4)
   05218 Melanoma
    103292479 (CDK4)
   05219 Bladder cancer
    103292479 (CDK4)
   05224 Breast cancer
    103292479 (CDK4)
   05222 Small cell lung cancer
    103292479 (CDK4)
   05223 Non-small cell lung cancer
    103292479 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103292479 (CDK4)
   05160 Hepatitis C
    103292479 (CDK4)
   05164 Influenza A
    103292479 (CDK4)
   05162 Measles
    103292479 (CDK4)
   05163 Human cytomegalovirus infection
    103292479 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103292479 (CDK4)
   05169 Epstein-Barr virus infection
    103292479 (CDK4)
   05165 Human papillomavirus infection
    103292479 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103292479 (CDK4)
   04934 Cushing syndrome
    103292479 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103292479 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103292479 (CDK4)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     103292479 (CDK4)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: CMGC group
  CDK family
   103292479 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 103292479
NCBI-ProteinID: XP_008146946
LinkDB
Position
7:52349345..52352387
AA seq 303 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDLWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEEDWPR
DVSLPRGAFPPRGPCPVQSVIPEMEKSGAQLLLEMLTFNPHKRISAFRALQHSYLQKEEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacccctcggtatgagccagtggctgagattggtgttggtgcctatgggacggtg
tacaaggcccgtgatccacacagtggccactttgtggccctcaagagcgtgagagtcccc
aatggaggaggtgccggagggggccttcccatcagcacagttcgtgaggtggccttactg
aggcggctggaggcttttgagcatcccaatgttgtccggctgatggatgtctgtgccacc
gcccgaactgaccgggagaccaaagtgaccctggtgtttgagcatgtggaccaagaccta
cggacatatctggacaaggcacccccaccaggcttgccagtggagaccatcaaggatctg
atgcgccagtttctaagaggcctggattttcttcatgccaattgcattgttcaccgagac
ctgaagccagagaatatcctggtgacaagtggtgggacagtcaagctggccgactttggc
ctggccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtac
cgtgccccggaagttcttctgcagtctacatacgcaacacctgtggacttgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctcttttctgcggaaactctgaagct
gaccaattgggcaaaatctttgacctgattgggctgcctccagaggaagattggccccga
gatgtgtctctaccccgaggagccttcccccccagagggccctgcccagtgcagtcggtg
atcccggagatggagaagtctggagcacagctgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttatctacaaaaggaggaaggt
aacccagagtga

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