Eptesicus fuscus (big brown bat): 103293360
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Entry
103293360 CDS
T09083
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus04120
Ubiquitin mediated proteolysis
efus04144
Endocytosis
efus04330
Notch signaling pathway
efus04668
TNF signaling pathway
efus04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
103293360 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
103293360 (ITCH)
04668 TNF signaling pathway
103293360 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103293360 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103293360 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
efus04131
]
103293360 (ITCH)
04121 Ubiquitin system [BR:
efus04121
]
103293360 (ITCH)
Enzymes [BR:
efus01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
103293360 (ITCH)
Membrane trafficking [BR:
efus04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
103293360 (ITCH)
Ubiquitin system [BR:
efus04121
]
Ubiquitin ligases (E3)
HECT type E3
103293360 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
103293360
NCBI-ProteinID:
XP_008147936
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All DBs
Position
12:34566687..34676940
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AA seq
862 aa
AA seq
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MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPMSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEKVVVTL
QLVGDKEPAETIGDLSVCLDGLQLESEVVTNGEATCAESASQNDDGSRPKEETRVNTNGS
DDLEDAGSGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDGNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHTIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagttacagtagatggacagtcaaagaagacagaaaaatgtaacaataca
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctatgagtaaattacat
tttcgcgtatggagtcaccagacactgaaatctgatgttttgttgggaactgctgcacta
gatatctatgaaacattaaagtcaaacaatatgaaacttgagaaagtagttgtgacttta
cagcttgtaggtgacaaagaaccagcagagacaataggagacttgtcagtttgtcttgat
gggctgcaattagaatctgaagttgttaccaatggtgaagctacatgtgcagaaagtgct
tcacagaatgatgatggctccaggcccaaggaggaaacaagagtgaacacaaatggatca
gatgaccttgaggatgcagggtctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggcggttttaagccttctagacctccaagaccttcacgaccacctcca
ccaaccccgcgtagaccagcttctgttaatggttcaccttctgccacttctgaaagtgat
ggctctagtacaggctctctgcctccaacaaatacaaattcaaatacatctgagggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtaccccaagctccactaccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacgcagggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcag
ctccaacgtagtcagcttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgcaacatcacaaaataaagaatttgatcctcttggtcccctgcca
cctggatgggaaaagagaacggatggcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtggatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccctagacaatggaccccag
atagcctatgtacgagactttaaggcaaagtttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagggaatggttctttcttttgtca
catgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttatatcaatccagatcacctgaagtattttcgttttatt
ggcaggtttattgccatggctcttttccatgggaaattcatagatacaggtttttcgttg
ccattctacaagcgtatcttgaacaaaccagttgggctcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctccgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggtttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggagttagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacataccatctaccgtcat
tatactaggacaagcaaacaaataatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattaccagttggagga
tttgctgacctcatggggagcaatggacctcaaaaattctgcattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctaccaccctataag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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