Eptesicus fuscus (big brown bat): 103296724
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Entry
103296724 CDS
T09083
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus04010
MAPK signaling pathway
efus04020
Calcium signaling pathway
efus04022
cGMP-PKG signaling pathway
efus04024
cAMP signaling pathway
efus04260
Cardiac muscle contraction
efus04261
Adrenergic signaling in cardiomyocytes
efus04270
Vascular smooth muscle contraction
efus04713
Circadian entrainment
efus04720
Long-term potentiation
efus04723
Retrograde endocannabinoid signaling
efus04724
Glutamatergic synapse
efus04725
Cholinergic synapse
efus04726
Serotonergic synapse
efus04727
GABAergic synapse
efus04728
Dopaminergic synapse
efus04742
Taste transduction
efus04911
Insulin secretion
efus04912
GnRH signaling pathway
efus04921
Oxytocin signaling pathway
efus04924
Renin secretion
efus04925
Aldosterone synthesis and secretion
efus04927
Cortisol synthesis and secretion
efus04929
GnRH secretion
efus04930
Type II diabetes mellitus
efus04934
Cushing syndrome
efus04935
Growth hormone synthesis, secretion and action
efus05010
Alzheimer disease
efus05020
Prion disease
efus05022
Pathways of neurodegeneration - multiple diseases
efus05031
Amphetamine addiction
efus05207
Chemical carcinogenesis - receptor activation
efus05410
Hypertrophic cardiomyopathy
efus05412
Arrhythmogenic right ventricular cardiomyopathy
efus05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103296724 (CACNA1C)
04020 Calcium signaling pathway
103296724 (CACNA1C)
04024 cAMP signaling pathway
103296724 (CACNA1C)
04022 cGMP-PKG signaling pathway
103296724 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103296724 (CACNA1C)
04929 GnRH secretion
103296724 (CACNA1C)
04912 GnRH signaling pathway
103296724 (CACNA1C)
04921 Oxytocin signaling pathway
103296724 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
103296724 (CACNA1C)
04924 Renin secretion
103296724 (CACNA1C)
04925 Aldosterone synthesis and secretion
103296724 (CACNA1C)
04927 Cortisol synthesis and secretion
103296724 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
103296724 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
103296724 (CACNA1C)
04270 Vascular smooth muscle contraction
103296724 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
103296724 (CACNA1C)
04727 GABAergic synapse
103296724 (CACNA1C)
04725 Cholinergic synapse
103296724 (CACNA1C)
04728 Dopaminergic synapse
103296724 (CACNA1C)
04726 Serotonergic synapse
103296724 (CACNA1C)
04720 Long-term potentiation
103296724 (CACNA1C)
04723 Retrograde endocannabinoid signaling
103296724 (CACNA1C)
09157 Sensory system
04742 Taste transduction
103296724 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
103296724 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103296724 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
103296724 (CACNA1C)
05020 Prion disease
103296724 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
103296724 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
103296724 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103296724 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
103296724 (CACNA1C)
05414 Dilated cardiomyopathy
103296724 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103296724 (CACNA1C)
04934 Cushing syndrome
103296724 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
efus04040
]
103296724 (CACNA1C)
Ion channels [BR:
efus04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
103296724 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
CAC1F_C
GPHH
PKD_channel
DUF4834
Motif
Other DBs
NCBI-GeneID:
103296724
NCBI-ProteinID:
XP_054574731
LinkDB
All DBs
Position
7:complement(14169768..14761829)
Genome browser
AA seq
2190 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKYPLPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK
VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT
CYNQEGITDVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPRHGITNFDNFAFAMLTVF
QCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKA
RGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTE
NVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLN
TLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVC
GGILETILVETKVMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLL
LFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM
AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKK
LARTASPEKKQEVVEKPAVEEAKEEKIELKSITADGESPPTTKINVDDFQPNENEDKGVY
PNPEATGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIV
NDSIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNAD
YVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKIL
RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYT
CSDSSKQTEAECKGNYITYKDGEVDHPIIQPRNWENSKFDFDNVLAAMMALFTVSTFEGW
PELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEY
KNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLA
MQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIID
VILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFR
LFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALND
TTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPHNSTEGEAPCGS
SFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAK
GRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTA
LRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFR
KFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSA
ASEDDIFRRAGGLFGNHVSYYQSDSRSTFPQTFTTQRPLHINKATNSPGDTESPSHEKLV
DSTFTPSSYSSTGSNANINNANNTALGRFPRPTRYPSSVSAVEGHGPPLSPAIRVQEAAW
TLSSKRCHSRESQIAMVCREEFSQDETYDAQMGDDAEYCSEPSLVSTDKLSYQDEESRQL
APPEDRRDTRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQAL
AVAGLSPLLQRSHSPTTFPRPCATPPATPSSRGWPPQPIPTLRLEGTESTEKLNSSFPSV
HCGSWSGEPTPCEAGSSAPRRARPVSLTVPSQAGAWGRQFHGSASSLVEAVLISEGLGQF
AQDPKFIEVTTQELADACDMTIEEMENAADNILSGGTQQSPNGTLLPFVNCRDQGQDRAG
GEEPGPCGPSQEPQRSEEELQDSRAYVSSL
NT seq
6573 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgaaaacacgaggatgtacatcccggaggaaaaccaccaaggttccaactat
gggagcccacgcccagctcatgccaacatgaatgccaacgcagcggcagggcttgccccc
gagcacatccccactccgggggcagccctgtcctggcaggcagccattgatgcggcccgg
caggctaagttgatgggaagcgctggcaatgcgaccatctccacagtcagctccacacag
cggaagcggcagcagtacgggaaacccaagaagcagggcagcaccactgccacacgccca
cctcgtgccctgctctgcctgactctgaagaaccccatccggagggcatgcatcagcatt
gtcgaatggaaatatcctttaccatttgaaatcattattttactgactatttttgccaat
tgtgtggccttagcgatctatattccttttccagaagatgactccaacgccaccaattcc
aacctggaacgagtggaatatctctttctcatcatttttactgtggaagcatttttaaaa
gtaatagcctatggacttctctttcaccctaacgcttacctccgcaacgggtggaattta
ctagattttataattgtggttgtagggctttttagtgcaattttagaacaagcaaccaaa
gctgacggggcaaatgctctaggagggaaaggggctggatttgatgtgaaggcgctgagg
gcattccgcgtgctgcgccccttgcggctggtgtctggagttccgagtctccaggtggtt
ctgaattccatcatcaaggccatggttcccctgctgcacatcgccctgctagtgctgttt
gtcatcattatctatgctatcattggcctggaactcttcatggggaagatgcataagacc
tgctacaaccaggagggcataacagatgttccagcagaagatgatccctccccttgtgct
ctggagacaggccatggacggcagtgtcagaacggcactgtgtgcaagcctgggtgggat
gggcccaggcatggcatcaccaactttgacaacttcgccttcgccatgctcacggtgttc
cagtgcatcaccatggaaggctggacagacgtgctatactgggtcaatgatgccgtagga
agggactggccctggatctattttgttacactaatcatcatagggtcattttttgtactt
aacttggttctcggtgtccttagcggagagttctccaaagagagggagaaggccaaggct
cggggggatttccaaaagctgcgagagaagcaacagctggaagaggacctgaaaggctac
ctggactggatcacacaggcggaagacatcgaccctgagaacgaggatgaaggaatggat
gaggagaaaccccgaaacatgagcatgcccacaagtgagacggagtctgtcaacactgag
aacgtggctggcggtgacatcgagggagaaaactgtggggccaggctggcccaccggatc
tccaagtcgaagttcagtcgctactggcgccggtggaatcggttctgcagaaggaagtgt
cgtgccgcagtcaagtccaatgtcttctactggctcgtgattttcctggtgttcctcaac
acgctcaccattgcctcagagcattacaaccagccgcactggctcacagaagtccaagac
acagccaacaaggctctcctggccctattcactgcggagatgctgctgaagatgtacagc
ctgggcctgcaggcctacttcgtgtccctcttcaaccgctttgactgcttcatcgtgtgc
gggggcatcctggagaccatcctggtggagaccaaggtcatgtccccgttgggcatctct
gtgctgagatgcgttcggctcctgaggatatttaaaatcaccaggtactggaactcctta
agcaacctggtggcatccttgctgaactcggtgcgctccatcgcctccctgctactactg
ctcttcctcttcatcatcatcttctccctcctggggatgcagctctttggaggaaagttc
aactttgatgagatgcagactcggaggagcacgtttgataactttccccagtccctcctc
accgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatg
gcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttc
atctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaacctggct
gatgctgagagcctcacatctgcccagaaggaggaagaagaagagaaggagagaaagaag
ctggccaggactgccagcccagagaagaaacaggaggtggtggagaagccagcagtggag
gaggccaaggaggagaaaattgagctgaaatccattacagctgacggagagtccccgccc
accaccaagatcaatgtggatgacttccagcccaatgaaaatgaggacaagggtgtctac
cccaacccggaagccacaggagaggaggatgaggaggagcctgagatgcccgtgggccca
cgcccacgcccactctcggagctgcaccttaaggaaaaggcagtgcccatgcctgaagcc
agtgcatttttcatcttcagccccaacaacaggtttcgcctccagtgccaccgcattgtc
aatgactcgatcttcaccaacctgatcctcttcttcatcctgctcagcagcatttccctg
gctgcggaggacccggtccagcacacctccttcaggaaccatattctgttttattttgat
attgtttttactaccattttcaccattgaaattgctctgaagatcctaggcaatgcagac
tatgtcttcactagtatctttacattagaaattatccttaagatgactgcttatggggct
ttcttacacaagggctccttttgccggaactacttcaacatcttggacctgctagtggtc
agcgtgtccctcatctcctttggcatccagtccagtgcaatcaatgttgtaaaaatcttg
cgagttctgcgcgtactcagacccctgagagccatcaaccgagccaaggggctaaagcat
gtggtccagtgcgtgtttgtggccatccgcaccatcgggaacatcgtgattgtcaccacg
ctgctgcagttcatgttcgcctgcatcggggtccagctcttcaagggaaagctctacacc
tgttcagacagttccaagcagacagaggcggaatgcaagggaaactacatcacatacaag
gacggggaggttgaccaccccatcatccagccccgcaactgggagaacagcaagtttgac
tttgacaatgtcctggcagccatgatggctctcttcactgtctccacctttgaggggtgg
ccagagctgctgtaccgctccatcgactcccacacggaagacaagggccccatatacaac
taccgcgtggagatctccatcttcttcatcatctacatcatcatcattgccttcttcatg
atgaacatcttcgtgggttttgtcatcgtcaccttccaggagcagggagagcaggagtac
aagaactgtgagctggacaagaaccagcgtcagtgtgtagaatatgccctcaaagccagg
cccctgcggaggtacatacccaagaaccagcaccagtacaaagtgtggtatgtggtcaac
tccacctactttgagtacctgatgttcgtcctcatcctgctcaacaccatctgcttggcc
atgcagcactacggtcagagctgcctgtttaaaatcgccatgaacatcctcaacatgctc
ttcaccggcctcttcactgtggagatgattctgaagctcattgcctttaaacccaagggt
tactttagtgatccctggaatgtttttgacttcctcatcgtaattggcagcataattgac
gtcattctcagtgaaactaatcactatttctgtgatgcatggaatacgtttgacgccttg
attgttgtgggtagcattgttgatatagcaatcaccgaggtaaacccagctgaacatacc
caatgctctccctttatgaatgcagaggagaactcccgcatctccatcaccttcttccgc
ctcttccgggtcatgcgcctggtcaagctgctgagccgtggggagggcatccggacgctg
ctgtggaccttcatcaagtccttccaggccctgccctacgtggcccttctgatcgtgatg
ctgttcttcatctatgccgtgatcgggatgcaggtgtttgggaaaattgccttgaatgac
acgacagagatcaaccggaacaacaactttcagaccttcccccaagctgtgctgctcctc
ttcaggtgtgccactggggaggcatggcaggacatcatgctggcctgcatgccagggaag
aagtgcgccccggagtctgagccccacaacagcacggaaggggaggcgccctgtggcagc
agcttcgccgtcttctacttcatcagcttctacatgctctgtgccttcctgattatcaac
ctctttgtagctgtcatcatggacaactttgactacctgacaagggactggtcaatcctt
ggtccccaccatttggacgaatttaaaagaatctgggcagagtatgaccctgaagccaag
ggtcgtatcaaacacctggatgtggtgaccctgctccggcggattcagccccccctgggt
tttgggaagctgtgccctcaccgtgtggcttgcaaacgtctggtctccatgaatatgcct
ctgaacagtgatgggacggtcatgttcaatgccaccctatttgccctggtccggacagcc
ctgaggatcaaaacagaagggaacctggaacaagccaatgaggagctgcgggccataatc
aagaagatctggaagcggaccagcatgaagctgctggaccaagtggtgccccctgcgggt
gatgatgaggtcacggtcggcaagttttatgctactttcctgatccaagagtacttccgg
aaattcaagaagcgcaaagagcagggcctcgtgggcaagccctcccagaggaacgccttg
tccctacaggctggcttgcgcacgctgcacgacatcgggcccgagatccgacgggccatc
tccggagacctgacagccgaggaggaactagacaaagccatgaaggaggctgtgtctgcc
gcctctgaagacgacatcttcaggagggccggtggcctgttcggcaaccacgtcagctac
taccaaagcgacagccgcagcaccttcccccagaccttcaccacgcagcgcccgctgcac
atcaacaaggccaccaacagcccaggcgacaccgagtccccgtcccatgagaaactggtg
gactccaccttcacccccagcagctactcatccactggctccaatgccaacatcaacaat
gccaacaacactgccctgggccgctttccccgccccacccgctaccccagctcggtcagc
gccgtggagggccacgggccccccttgtctcccgccatccgggtgcaggaggcagcgtgg
acgctcagctccaagaggtgccactcccgggagagccagatagccatggtgtgtcgggag
gagttttctcaggacgagacctatgacgcgcagatgggtgacgacgcggagtactgcagt
gagcccagcctggtctccacagacaagctctcctaccaggatgaggaaagccgacagttg
gcgccgccggaggacaggagggacacccggcaatctccaaagaggggcttcctccgctct
gcctccctgggtcggagggcctcgttccacctagaatgtctgaagcgacagaagaatcaa
gggggagacatctctcagaagacagtcctgcccttgcacctggttcatcaccaggcattg
gcagtggcgggcctgagccccctcctccagagaagccattctcccaccaccttcccccgg
ccgtgtgccacccccccggccacgcccagcagccgaggctggcccccgcagcccatcccc
acccttcggctggaaggaaccgagtccaccgagaaactcaacagcagcttcccatccgtc
cactgcggctcctggtcgggggagcccacgccctgcgaggcgggcagcagcgccccgcgg
agagcccggccggtgtccctcactgtgcccagccaggccggggcctggggcaggcagttc
cacggcagtgccagcagcctggtggaagcagtcttgatttcggaaggactggggcagttt
gcccaagatcccaagtttatcgaggtcacaacccaggagctggctgacgcctgcgacatg
accatcgaggagatggagaacgctgcagacaacatcctcagtgggggcacccagcagagc
cccaacggcaccctattaccttttgttaactgcagggaccaggggcaggacagagcaggg
ggcgaggagcccgggccctgtgggcccagccaggagcctcagaggagcgaggaggagctg
caggacagcagagcctacgtcagcagcctgtag
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integrated database retrieval system
