Eptesicus fuscus (big brown bat): 103296941
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Entry
103296941 CDS
T09083
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00590
Arachidonic acid metabolism
efus01100
Metabolic pathways
efus01523
Antifolate resistance
efus04726
Serotonergic synapse
efus04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
103296941 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
103296941 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
103296941 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103296941 (ALOX12)
Enzymes [BR:
efus01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
103296941 (ALOX12)
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GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
103296941
NCBI-ProteinID:
XP_054565118
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Position
20:complement(11576657..11589602)
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AA seq
663 aa
AA seq
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MGRYRICVATGAWLFSGSFNRVQLWLVGERGEAELELQLRPVRGQVEEFEQDVPQDLGPL
QFVKLRKHHSLVDNAWFCDRITVQGPGASEEAAFPCYRWVQGDGLLTLPEGTARLAGDNA
SDVFQKHREKELKERQQIYCWATWKEGLPLTIAAGSEDDLPPNTRFHEEKRLDFEWTLKA
GALEMALKRVYTLLSSWNHLEDFDQIFWGQKSNLAEKVHQRWQDDELFGYQFLNGANPML
LRRSTSLPPRLVLPSGMEELRAQLEKELQKGSLFEADFILLDGIPANVIREEQQYLAAPL
VMLKMEPSGKLLPMVIQIQPPNPSSPTPSLFLPSDPPLAWLLAKSWVRNSDFQLHQLKYH
LLNTHLLAEVIAVATMRCLPGLHPVFKLLIPHTRYTMEINTRARTQLISDGGIFDKAVST
GGGGHVQLMRRAMAQLTYRSLCPPDDLADRGLLGIPSALYAHDALRLWEIIARYVEGIVH
LFYHGDDFVRGDPELQAWCREITEVGLCQAQDRGFPVSFQSLNQLCHFLTMCVFTCTAQH
GAINKGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVQQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSGSKTKAVLNQFQTDLENWEREMTARNEQLDLAYEYLKPSNIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatctgcgtggccaccggggcctggctcttctccgggtcgttcaac
cgcgtgcagctgtggctggtcggggagcgcggggaggcggagctggagctgcagctgcgg
ccggtgcggggccaggtggaggagtttgagcaggacgttccccaggacttggggccactg
cagttcgtgaagttgcgcaaacaccactccctggtggacaacgcctggttctgcgaccgc
atcaccgtgcagggcccaggagcctcagaggaggccgccttcccctgctaccgctgggtg
cagggcgacggcctgctgaccctgcccgagggcaccgctcgcctggcaggagacaatgca
tcggatgtgttccagaaacatcgagagaaggaactgaaggaaagacaacaaatatactgc
tgggccacctggaaggaagggttacccctgacaatagctgccggcagtgaggatgatcta
cctccaaatacgagattccatgaggagaagaggctggactttgagtggacactgaaggct
ggggcactggagatggccctcaagcgtgtttacaccctcctgagctcctggaatcatctg
gaggattttgatcagatcttctggggccagaagagcaatctggctgagaaggttcaccaa
cgctggcaagatgatgagctttttggctaccagttcctcaatggcgccaaccccatgctg
ttgagacgctccacctctctgccccccaggctggtgctgccctcagggatggaggagctt
cgggcccagttggagaaagaactccagaagggttccctgtttgaagctgacttcatcctt
ctggatggaattccagccaatgtgatccgagaagagcagcagtacctggctgcccccctt
gtcatgctgaagatggagcccagtgggaagctgctgcccatggtcatccagatccagcct
cccaaccccagctccccgaccccatcactgttcctgccttcagatcctccacttgcctgg
ctcctggcaaagtcctgggttcgaaattcagatttccaactgcaccagctcaaatatcac
ttgctgaacactcatctgctggctgaagtcatcgctgtcgccaccatgaggtgtctccca
ggactgcaccctgtcttcaagctcctgatcccacacacccgctacaccatggagatcaac
acacgggcaaggacccaactcatctcagatggaggtatatttgataaggctgtgagcaca
ggtggagggggccatgtgcagttgatgcgtcgggccatggctcagctgacctaccgctcc
ctctgtcctcctgacgatctggctgaccggggcctgctgggaatcccaagtgccctctat
gcccatgatgctttacggctctgggagatcattgctcggtacgtggaggggattgtccac
ctcttctaccacggggatgacttcgtgagaggggaccctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccaggaccgaggtttccctgtctccttccag
tctctgaatcaactctgccatttccttaccatgtgtgtattcacgtgcacagcccagcat
ggggccatcaataagggccagctggactggtatgcctgggtccctaatgccccgtgcaca
atgcgaatgcccccacccaccaccaaggaagatgtgacaatggccacagtgatgggctca
ctccctgatgtccaacaggcctgtcttcaaatgaccatcacatggcatctgggtcgacgc
cagccagacatggttcctctggggcatcacaaagaaaagtacttctcgggctccaagacc
aaagctgtactaaaccaattccaaacagatctggaaaactgggaaagggaaatgacagcc
cggaatgagcaacttgaccttgcctacgaatacttaaagcccagcaacatagagaacagt
atcactatctga
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