KEGG   Eptesicus fuscus (big brown bat): 103298291
Entry
103298291         CDS       T09083                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2 isoform X1
  KO
K04364  growth factor receptor-bound protein 2
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01521  EGFR tyrosine kinase inhibitor resistance
efus01522  Endocrine resistance
efus04010  MAPK signaling pathway
efus04012  ErbB signaling pathway
efus04014  Ras signaling pathway
efus04062  Chemokine signaling pathway
efus04068  FoxO signaling pathway
efus04072  Phospholipase D signaling pathway
efus04150  mTOR signaling pathway
efus04151  PI3K-Akt signaling pathway
efus04380  Osteoclast differentiation
efus04510  Focal adhesion
efus04517  IgSF CAM signaling
efus04540  Gap junction
efus04550  Signaling pathways regulating pluripotency of stem cells
efus04630  JAK-STAT signaling pathway
efus04650  Natural killer cell mediated cytotoxicity
efus04660  T cell receptor signaling pathway
efus04662  B cell receptor signaling pathway
efus04664  Fc epsilon RI signaling pathway
efus04714  Thermogenesis
efus04722  Neurotrophin signaling pathway
efus04910  Insulin signaling pathway
efus04912  GnRH signaling pathway
efus04915  Estrogen signaling pathway
efus04917  Prolactin signaling pathway
efus04926  Relaxin signaling pathway
efus04935  Growth hormone synthesis, secretion and action
efus05034  Alcoholism
efus05160  Hepatitis C
efus05161  Hepatitis B
efus05163  Human cytomegalovirus infection
efus05165  Human papillomavirus infection
efus05200  Pathways in cancer
efus05203  Viral carcinogenesis
efus05205  Proteoglycans in cancer
efus05206  MicroRNAs in cancer
efus05207  Chemical carcinogenesis - receptor activation
efus05208  Chemical carcinogenesis - reactive oxygen species
efus05210  Colorectal cancer
efus05211  Renal cell carcinoma
efus05213  Endometrial cancer
efus05214  Glioma
efus05215  Prostate cancer
efus05220  Chronic myeloid leukemia
efus05221  Acute myeloid leukemia
efus05223  Non-small cell lung cancer
efus05224  Breast cancer
efus05225  Hepatocellular carcinoma
efus05226  Gastric cancer
efus05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103298291 (GRB2)
   04012 ErbB signaling pathway
    103298291 (GRB2)
   04014 Ras signaling pathway
    103298291 (GRB2)
   04630 JAK-STAT signaling pathway
    103298291 (GRB2)
   04068 FoxO signaling pathway
    103298291 (GRB2)
   04072 Phospholipase D signaling pathway
    103298291 (GRB2)
   04151 PI3K-Akt signaling pathway
    103298291 (GRB2)
   04150 mTOR signaling pathway
    103298291 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103298291 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103298291 (GRB2)
   04540 Gap junction
    103298291 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    103298291 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    103298291 (GRB2)
   04660 T cell receptor signaling pathway
    103298291 (GRB2)
   04662 B cell receptor signaling pathway
    103298291 (GRB2)
   04664 Fc epsilon RI signaling pathway
    103298291 (GRB2)
   04062 Chemokine signaling pathway
    103298291 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103298291 (GRB2)
   04912 GnRH signaling pathway
    103298291 (GRB2)
   04915 Estrogen signaling pathway
    103298291 (GRB2)
   04917 Prolactin signaling pathway
    103298291 (GRB2)
   04926 Relaxin signaling pathway
    103298291 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    103298291 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    103298291 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103298291 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    103298291 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103298291 (GRB2)
   05206 MicroRNAs in cancer
    103298291 (GRB2)
   05205 Proteoglycans in cancer
    103298291 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    103298291 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    103298291 (GRB2)
   05203 Viral carcinogenesis
    103298291 (GRB2)
   05231 Choline metabolism in cancer
    103298291 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103298291 (GRB2)
   05225 Hepatocellular carcinoma
    103298291 (GRB2)
   05226 Gastric cancer
    103298291 (GRB2)
   05214 Glioma
    103298291 (GRB2)
   05221 Acute myeloid leukemia
    103298291 (GRB2)
   05220 Chronic myeloid leukemia
    103298291 (GRB2)
   05211 Renal cell carcinoma
    103298291 (GRB2)
   05215 Prostate cancer
    103298291 (GRB2)
   05213 Endometrial cancer
    103298291 (GRB2)
   05224 Breast cancer
    103298291 (GRB2)
   05223 Non-small cell lung cancer
    103298291 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    103298291 (GRB2)
   05160 Hepatitis C
    103298291 (GRB2)
   05163 Human cytomegalovirus infection
    103298291 (GRB2)
   05165 Human papillomavirus infection
    103298291 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    103298291 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103298291 (GRB2)
   01522 Endocrine resistance
    103298291 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:efus04131]
    103298291 (GRB2)
Membrane trafficking [BR:efus04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    103298291 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 103298291
NCBI-ProteinID: XP_008153285
LinkDB
Position
20:complement(48294247..48353444)
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagatggcttcattcccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgac
ggggccttccttatccgagagagcgagagtgctcctggggacttctccctctccgtcaag
tttggaaatgatgtgcagcactttaaggtgctccgagatggagctggaaagtatttcctc
tgggtggtgaagttcaattctttgaatgagctggtagattatcacagatctacatccgtc
tccagaaaccagcagatattcctccgggacatagaacaggtgccacagcagccgacgtac
gtccaagccctctttgactttgacccccaggaggatggagagctggggttccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgtttccccgcaattacgtcacccccgtgaaccggaacgtctaa

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