Eptesicus fuscus (big brown bat): 103299461 Help Entry 103299461         CDS       T09083                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism efus  Eptesicus fuscus (big brown bat) Pathway efus04022   cGMP-PKG signaling pathway efus04068   FoxO signaling pathway efus04081   Hormone signaling efus04140   Autophagy - animal efus04152   AMPK signaling pathway efus04211   Longevity regulating pathway efus04213   Longevity regulating pathway - multiple species efus04910   Insulin signaling pathway efus04920   Adipocytokine signaling pathway efus04923   Regulation of lipolysis in adipocytes efus04930   Type II diabetes mellitus efus04935   Growth hormone synthesis, secretion and action efus05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:efus00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103299461 (IRS4)    04022 cGMP-PKG signaling pathway     103299461 (IRS4)    04152 AMPK signaling pathway     103299461 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     103299461 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103299461 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103299461 (IRS4)    04923 Regulation of lipolysis in adipocytes     103299461 (IRS4)    04920 Adipocytokine signaling pathway     103299461 (IRS4)    04935 Growth hormone synthesis, secretion and action     103299461 (IRS4)   09149 Aging    04211 Longevity regulating pathway     103299461 (IRS4)    04213 Longevity regulating pathway - multiple species     103299461 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     103299461 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103299461 (IRS4) SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  103299461 NCBI-ProteinID:  XP_054573003 LinkDB All DBs Position 1:complement(78452496..78456302) Genome browser AA seq 1268 aa AA seqDB search MASCSFARHRATRSLRAAAAATAAALAAVGTTPLLSSGTLTALIGTGSSCPGAMWLSSAT GSRPHSESEEEDLPVGEEVCKHGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGASAPALIPPRRVITLSQCFSVSQRADARYRHLIALFTQDEYLALV AENESEQESWYLLLSRLILESKRRRCGTPCAQLDGEPVALAAPAVAEPPFYKDVWQVIVK PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMKALCADEYRARCRSYSISIGAHLLTLLSTRRH RDMVPLEPGGWLRRSRFEQFCHLRAVGDGEDEMLLTRHSVTHSEPVPHSRRGRLHLPRAR RSGRTISVPASFFRRLAPCRVRARQTAETPSDRVCLFSEASSSGSGNSGEEGNPQGQAGQ EGNTGDYMPMNNWGSGGGQGSSGQSSSSQSSGGNQCSGRGLGSGGGQGCSGGQGSSRQGS GSQGAGRNQCSGHGQGPTGGHGSSSGQGASGGHGSGSGQGPGDGHNSGGGKNSGGGKGSG SGKDSDGNGEWAKSLKKRSYFGKLIQSKQQEMPPPPPPPPPPPPAGATGGKGKSGGRFRL YFCADRAATKERKEVKDTETLEGAARGPHRARAFNEDEDDPYVPMRPGVAAPLESSSDYM PMAPQNVSASVKYHSRSSFEDSRGYMMMFPRVSPPPAPIPPKASDPDKDDNSKDNDSDSD YMFMAPGAGAIPKKTPNPQGGSSSKSWSSYFSLPKTFQSSPLGQSDHSEYVPMFSGKLLG KGLDKKGSSIRGPKYAASKSSVEGFEATLQSISKPGDGSSPPKFSDDGPPKDQAKRPNRL SFITKENKIESKPQKPTREQREADNFSDYANIDFPKRSSNTPAPFTQGLPHSWGIIANPR QSAFSQYVNIEFRVPFRNAVNVLSNLLRAVPGANRFFLEGDRWPLLPLLTSATGSNANEE ECEYIEVTFNPAMAPPLTFGDRAIRYDAETGRMYVVDPFSECCMDISLSPSRCSEPPPVA RLLQEEELERRSTQSRSQSIFASTRAAVSAFPTDSLERDLYTTLGSTSAVGAEPTLAVGR ALAASSALAAVPGLGATAAGFEAASGLNSASACWLQPLANAAGAQAVRGAHVVAGSSNPR AQNPSSDFARGENGAGEASAAAAAPPPPPRHWLPGLPEREDSDEEDTYVRMDFAGPEDKK FYSPQRGW NT seq 3807 nt NT seq  +upstreamnt  +downstreamnt atggcgagttgctctttcgctcgccaccgagcgaccaggagtctgagagctgcagcagcg gctacagcggcagctctagctgcagtggggaccaccccacttctttcctcgggaacccta accgcactcattgggaccgggtcttcttgtccgggagccatgtggctttcctccgccact ggctcccggccacactccgagtctgaagaagaggacctccccgtcggcgaggaagtctgt aaacacggctacctgcggaagcagaagcatgggcacaggcgctactttgtgctcaaactc gagaccgccgacgccccagctcggctcgaatactacgaaaatgccaggaagttccggcac agtgtccgcgctgcggccgctgcagcagccgccgccgcctcgggcgcctcagccccagcg ctcatcccgccgcggcgcgtgatcaccctgtcccagtgcttctccgtgagccagcgagcc gacgccaggtaccgacatctcatcgctcttttcacccaggatgagtacttggctttggtg gccgaaaacgagtcggagcaagagagctggtacttgctgctcagccgcctcatcctcgag agcaaacgccgccgctgcggcacgccctgcgcgcagctggatggagagccggtcgcgctg gcggccccagcggtggcggagccaccattctacaaagatgtgtggcaggtaatagtcaaa cccagggggctggggcatagaaaagagctgagcggcgtgttccggctctgtcttaccgac gaggaggttgtgtttgtgaggctgaataccgaggtggccagcgtggtcgtccagctcctg agcatccgtcgctgcggacactctgagcagtatttcttcttggaagtcggcaggtcgacc gtcatcggtccaggggagctctggatgcaggtcgatgactgtgtggtggcccaaaatatg catgagctctttttggagaagatgaaagccttgtgtgcagacgaataccgagcccgctgc cgcagctacagcatcagcatcggggcccacctgttaaccctgctgtccactaggaggcac cgggacatggtgcctctggagcccggaggctggctaagaaggtcccgctttgaacaattt tgccacctcagggccgtaggtgacggagaagacgagatgctcctcaccaggcactccgta acacacagcgagcctgtgccccactccaggcgaggaagactgcacctgcccagagcgcgc aggtccgggagaacgatttctgtgccagccagcttttttcgacgcctagcaccctgccgg gtgcgtgctcggcagactgcagaaacccccagcgacagagtttgcctgttttctgaagcg tctagttccggttctggcaactctggggaagaaggcaatcctcaaggccaagcgggtcag gaaggaaacacaggtgactacatgcccatgaacaattggggctcaggaggtggccagggc tcaagcggccaaagctccagtagccagagctcaggaggaaaccagtgctcaggcaggggg ctgggctctggaggtggccagggatgtagtggtggccagggttcaagccgccagggctca gggagccagggtgcaggacgaaaccaatgctcaggacatggccagggccccacaggtggg cacggttccagcagtggccagggagccagtggtgggcacggttcaggtagtggccaggga ccaggagatggccataattcaggtggtggcaagaactctggagggggcaaaggctctgga agtgggaaagactccgatggcaatggtgaatgggcaaaatctctgaagaaaagatcctac tttggcaagttaattcaaagcaagcaacaggaaatgccaccacctccaccacctccacct ccgcccccgccagctggagcaactggtggaaaagggaagtctgggggaaggttccgactt tatttttgtgctgacagagcagccacaaaggaacgcaaagaagtcaaagatacagagacc ctggaaggtgcagctcggggtcctcacagagccagagcttttaatgaagatgaggacgac ccttacgtgccaatgaggccaggggtggctgcccctctggaaagctccagtgattatatg ccaatggctcctcaaaatgtttctgcttcagtaaagtatcactcccgatcctcttttgaa gattcaagagggtacatgatgatgtttcccagagtgagcccaccacctgccccaattcct ccaaaagcatctgatcctgataaagatgataactctaaggacaatgacagtgacagtgat tacatgtttatggctcctggagccggtgcaattccaaaaaaaaccccaaatccccaggga ggctcttcctccaaaagttggagctcctacttctctctgccaaaaacttttcagagctcc ccattgggacagagtgaccacagtgagtatgtaccaatgttctctggaaaactcctgggg aaaggcctagacaaaaaagggtcttcaatcaggggccccaaatatgcagcttcaaagtct tcagttgagggctttgaagctaccctccagtcaatctcaaagcctggagatgggagttca cctccaaagttttcagatgatgggccccctaaggaccaggctaagagacctaaccgactt tcttttattacaaaagaaaataaaatcgagtcaaaaccacaaaagcccacacgtgagcag agagaggctgacaactttagtgactacgccaacattgacttccctaaaagaagtagtaat acgccagccccctttactcaaggactgccacattcctggggcataattgctaaccccaga cagtcagccttttctcaatacgtgaatattgagttcagagtgccatttcgaaatgcagta aacgtcctctcaaatcttttaagagctgttccaggtgccaaccgcttctttctggaaggt gataggtggccacttctgcctcttcttaccagtgctacaggtagcaatgctaatgaggaa gagtgtgagtacattgaagtgactttcaacccagcaatggcaccacccttgacttttggt gaccgtgccattcgctatgatgctgaaacaggtcgaatgtatgtggtcgacccattttct gagtgctgtatggacatttctctctcccctagccgctgctcagaaccaccacctgtagct aggctgctgcaggaagaagagctagagagaagaagcacacaaagccgttcgcaaagtatc tttgcatccaccagagctgctgtctcggctttccctaccgacagcctggagagagacctc tacaccaccctaggctccacctcagctgtgggcgctgagccaaccttagctgtaggccgg gctctagccgcctcctccgccctcgccgcggtcccgggcctgggagcaaccgccgcgggc ttcgaggctgcctctggacttaactctgcctctgcctgctggctccaacctcttgctaat gctgctggtgcccaagcagtaaggggtgcccacgtcgttgccggtagctccaaccctaga gcccaaaacccatcttcagactttgccagaggtgagaacggggctggtgaggcttccgct gcagctgccgctccccccccaccacctcgccactggttgcctgggctccccgagcgagaa gattctgacgaggaagacacatacgtgagaatggacttcgccggacctgaggacaaaaag ttctactctccccaaagaggttggtaa

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