Eptesicus fuscus (big brown bat): 103300478 Help Entry 103300478         CDS       T09083                                  Symbol TNF Name (RefSeq) tumor necrosis factor isoform X1   KO K03156   tumor necrosis factor superfamily, member 2 Organism efus  Eptesicus fuscus (big brown bat) Pathway efus01523   Antifolate resistance efus04010   MAPK signaling pathway efus04060   Cytokine-cytokine receptor interaction efus04061   Viral protein interaction with cytokine and cytokine receptor efus04064   NF-kappa B signaling pathway efus04071   Sphingolipid signaling pathway efus04150   mTOR signaling pathway efus04210   Apoptosis efus04217   Necroptosis efus04350   TGF-beta signaling pathway efus04380   Osteoclast differentiation efus04612   Antigen processing and presentation efus04620   Toll-like receptor signaling pathway efus04621   NOD-like receptor signaling pathway efus04622   RIG-I-like receptor signaling pathway efus04625   C-type lectin receptor signaling pathway efus04640   Hematopoietic cell lineage efus04650   Natural killer cell mediated cytotoxicity efus04657   IL-17 signaling pathway efus04660   T cell receptor signaling pathway efus04664   Fc epsilon RI signaling pathway efus04668   TNF signaling pathway efus04920   Adipocytokine signaling pathway efus04930   Type II diabetes mellitus efus04931   Insulin resistance efus04932   Non-alcoholic fatty liver disease efus04933   AGE-RAGE signaling pathway in diabetic complications efus04936   Alcoholic liver disease efus04940   Type I diabetes mellitus efus05010   Alzheimer disease efus05014   Amyotrophic lateral sclerosis efus05020   Prion disease efus05022   Pathways of neurodegeneration - multiple diseases efus05132   Salmonella infection efus05133   Pertussis efus05134   Legionellosis efus05135   Yersinia infection efus05140   Leishmaniasis efus05142   Chagas disease efus05143   African trypanosomiasis efus05144   Malaria efus05145   Toxoplasmosis efus05146   Amoebiasis efus05152   Tuberculosis efus05160   Hepatitis C efus05161   Hepatitis B efus05163   Human cytomegalovirus infection efus05164   Influenza A efus05165   Human papillomavirus infection efus05166   Human T-cell leukemia virus 1 infection efus05168   Herpes simplex virus 1 infection efus05169   Epstein-Barr virus infection efus05170   Human immunodeficiency virus 1 infection efus05171   Coronavirus disease - COVID-19 efus05205   Proteoglycans in cancer efus05310   Asthma efus05321   Inflammatory bowel disease efus05322   Systemic lupus erythematosus efus05323   Rheumatoid arthritis efus05330   Allograft rejection efus05332   Graft-versus-host disease efus05410   Hypertrophic cardiomyopathy efus05414   Dilated cardiomyopathy efus05417   Lipid and atherosclerosis efus05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:efus00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103300478 (TNF)    04350 TGF-beta signaling pathway     103300478 (TNF)    04064 NF-kappa B signaling pathway     103300478 (TNF)    04668 TNF signaling pathway     103300478 (TNF)    04071 Sphingolipid signaling pathway     103300478 (TNF)    04150 mTOR signaling pathway     103300478 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     103300478 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     103300478 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     103300478 (TNF)    04217 Necroptosis     103300478 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     103300478 (TNF)    04620 Toll-like receptor signaling pathway     103300478 (TNF)    04621 NOD-like receptor signaling pathway     103300478 (TNF)    04622 RIG-I-like receptor signaling pathway     103300478 (TNF)    04625 C-type lectin receptor signaling pathway     103300478 (TNF)    04650 Natural killer cell mediated cytotoxicity     103300478 (TNF)    04612 Antigen processing and presentation     103300478 (TNF)    04660 T cell receptor signaling pathway     103300478 (TNF)    04657 IL-17 signaling pathway     103300478 (TNF)    04664 Fc epsilon RI signaling pathway     103300478 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     103300478 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     103300478 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     103300478 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103300478 (TNF)    05170 Human immunodeficiency virus 1 infection     103300478 (TNF)    05161 Hepatitis B     103300478 (TNF)    05160 Hepatitis C     103300478 (TNF)    05171 Coronavirus disease - COVID-19     103300478 (TNF)    05164 Influenza A     103300478 (TNF)    05168 Herpes simplex virus 1 infection     103300478 (TNF)    05163 Human cytomegalovirus infection     103300478 (TNF)    05169 Epstein-Barr virus infection     103300478 (TNF)    05165 Human papillomavirus infection     103300478 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     103300478 (TNF)    05135 Yersinia infection     103300478 (TNF)    05133 Pertussis     103300478 (TNF)    05134 Legionellosis     103300478 (TNF)    05152 Tuberculosis     103300478 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     103300478 (TNF)    05144 Malaria     103300478 (TNF)    05145 Toxoplasmosis     103300478 (TNF)    05140 Leishmaniasis     103300478 (TNF)    05142 Chagas disease     103300478 (TNF)    05143 African trypanosomiasis     103300478 (TNF)   09163 Immune disease    05310 Asthma     103300478 (TNF)    05322 Systemic lupus erythematosus     103300478 (TNF)    05323 Rheumatoid arthritis     103300478 (TNF)    05321 Inflammatory bowel disease     103300478 (TNF)    05330 Allograft rejection     103300478 (TNF)    05332 Graft-versus-host disease     103300478 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     103300478 (TNF)    05014 Amyotrophic lateral sclerosis     103300478 (TNF)    05020 Prion disease     103300478 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     103300478 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103300478 (TNF)    05418 Fluid shear stress and atherosclerosis     103300478 (TNF)    05410 Hypertrophic cardiomyopathy     103300478 (TNF)    05414 Dilated cardiomyopathy     103300478 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103300478 (TNF)    04940 Type I diabetes mellitus     103300478 (TNF)    04936 Alcoholic liver disease     103300478 (TNF)    04932 Non-alcoholic fatty liver disease     103300478 (TNF)    04931 Insulin resistance     103300478 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     103300478 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     103300478 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:efus04052]     103300478 (TNF)    00536 Glycosaminoglycan binding proteins [BR:efus00536]     103300478 (TNF) Cytokines and neuropeptides [BR:efus04052]  Cytokines   Tumor necrosis fators    103300478 (TNF) Glycosaminoglycan binding proteins [BR:efus00536]  Heparan sulfate / Heparin   Cytokines    103300478 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  103300478 NCBI-ProteinID:  XP_054578104 LinkDB All DBs Position 10:1730953..1738593 Genome browser AA seq 231 aa AA seqDB search MSTESMIRDVELAEEALPKKAGGPQGSRRCLCISLFSFLLVAGATTLFCLLHLGVIGPQR EEQFPMGSLPLAQTLGLSSRTPGDKPVAHVVANQQTVGQLQWQSKVANALLANGVNLTDN QLVVPLSGLYLIYSQVLFKGRGCPHGPLLLTHIVSRFAVSYKEKINLLYAIKSPCQRESP EGTEAMPWYEPIYLGGVFQLDKGDRLSAEINLPDYLDFSESGQVYFGIVAL NT seq 696 nt NT seq  +upstreamnt  +downstreamnt atgagcactgagagcatgatccgcgacgtggagctggcggaggaggcgctccccaagaag gcagggggcccccagggctccagacggtgcttgtgcatcagcctcttctccttcctcctc gtggcaggagccaccacactcttctgcctgctgcacttgggggtgatcggcccccagagg gaagagcagttcccgatgggcagcctcccactggcccagaccctcggattatcttctcga accccaggtgacaagcctgtggcccatgttgtagcaaaccagcaaactgtggggcagctg cagtggcagagcaaggtggccaacgcgctcctggccaatggtgtcaacctgacggacaac cagctggtggtgccattgagtgggctgtacctgatctactcccaggtcctcttcaagggc agaggctgccctcacggccccctgctgctcacccacatcgtcagccgctttgccgtctcc tacaaggagaagatcaacctcctctatgccatcaagagcccctgccagcgggagagccca gaggggacggaggccatgccctggtacgagcccatctacctggggggagtcttccagctg gacaagggcgatcggctcagtgccgagatcaacctgcccgactatctcgatttttccgag tccgggcaggtctactttgggatcgttgccctgtga

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