Eptesicus fuscus (big brown bat): 103305493
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Entry
103305493 CDS
T09083
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus05200
Pathways in cancer
efus05223
Non-small cell lung cancer
efus05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103305493 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103305493 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
103305493 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efus01001
]
103305493 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
efus04090
]
103305493 (ALK)
Enzymes [BR:
efus01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103305493 (ALK)
Protein kinases [BR:
efus01001
]
Receptor tyrosine kinases (RTK)
ALK family
103305493 (ALK)
CD molecules [BR:
efus04090
]
Proteins
103305493 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
MAM
Pkinase
Gly_rich
Ldl_recept_a
Motif
Other DBs
NCBI-GeneID:
103305493
NCBI-ProteinID:
XP_008160494
LinkDB
All DBs
Position
16:complement(13288995..13880767)
Genome browser
AA seq
1615 aa
AA seq
DB search
MGAIGLLWLLLPLLSAAASGTGAETETNQSVGSLAMGSALQPREPLSYSRLQRKSLAVDF
VVPSLFRVYARELLLPPPSPSQPRASRLEARSSLALDCAPLLRLVGPPPGVRTAGASSPA
PARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEATAGLLQFNLSELFSWWI
RHGEGRLRIRLMPEKKASEVGREGKLSAAIRASQPRLLFQIFRTGHSSLESPTNLPSPVP
ESFAWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRVPSEEA
SQMDLLDGPEAEHSKEMPRGSFLLLNTSANSKHTILSPWMRSSSEHCRLAVSVHRHLQPS
GRYVAQLLPHNEAGREILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVD
FFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQGEDEDQLCSKLPAGF
YCSFEDGFCGWSQGTLSPHAPEWQVKTLKEARFQDRQGHALLLNTTEVPTSASATVTSTT
FPAPMKNSPCELRMSWLIQGVLRGNVSLVLVENRTGKEQSRMVWHVATNEGLSLWQWTVL
PLLDVADRFWLQIVAWWGQGSRATVAFDNISISLDCYLTISGEDKMLQNTAPKSRNLFER
NPNKEMKLWENIPRETPLFDPTVHWLFTTCGASGPHGPTQAQCNNAYRNTNLSVVVGSEG
PLKGIQTWKVPATDTYSISGYGAAGGKGGRNTMMRSHGVSVLGIFNLEKDDTLYILVGQQ
GEDACPSTNRLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPL
IIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGYSGAAGGGGGWNDNTSLLWSGKSLLE
GATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASDNDPEMDGEDGVSF
ISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEGDECHLDPESHQVICFCDHGTVLAEDG
VSCVVSPTPEPRLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEY
KLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGM
PNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLEL
MAGGDLKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT
CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVL
LWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAI
ILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGIPPLLVSPPAGKGGDKQD
AAAPAPLPSTSSGKAVRKPPAAEVNVRVARGPAVGGGHVNMAFAQSNPPPELHKVQRSRN
KPTSLWNPTYGSWFTEKPARKARPPAQKEPERGGPGHGGGPVPPSAAAGRVPGAALLLEP
SSLTASVKEVPLFRLRHFPCGTVNYGYQQQGLPLEAAAPGASHYQDTALQSQPGP
NT seq
4848 nt
NT seq
+upstream
nt +downstream
nt
atgggagccataggactcttatggctgctgctgcccctgctttcagcagcagcctctggc
actggggccgagaccgagaccaaccagagcgtgggctcactggccatggggtctgcgctg
cagccccgggagccgcttagctactcgcgcctgcagaggaagagcctagcggtggacttc
gtggtgccctcgctcttccgcgtctatgcccgggagctgctgctgccgccgccatccccc
tcgcagccaagggctagcaggctggaggcgcgcagctcgctggctctagattgcgccccg
ttgcttaggctagtggggccaccacccggagttaggacggcgggagccagctcgccagcc
ccggcacggacgctgtccagggtgctgaagggcggctcggttcgcaagctacggcgggcc
aagcagcttgtgctagagttgggagaggaggcgattcttgagggctgtgttgggccccca
gaggaggcgactgcagggctgctccagttcaacctcagcgagctgttcagctggtggatt
cgccatggcgaagggcggctgaggatccgcctgatgcctgagaagaaggcgtccgaagtg
ggcagagagggaaagctgtcagcagcgatccgcgcctctcagccccgccttctctttcag
atcttcaggaccggtcacagctccttagagtcaccgacaaacctgccttctcctgttcct
gaatcttttgcatggaatctgacctggataatgaaagattccttcccttttctgtctcat
cgcagccgatatgggctggagtgcagctttgacttcccctgtgagctggagtactcccct
ccactgcatgacctcaggaaccagagctggtcctggcgccgtgtcccctcggaggaggcc
tcccagatggacctgctggatgggcccgaggcagagcattccaaggagatgcccagaggc
tccttcctcctcctcaacacctcagcaaactccaagcataccatcttgagcccgtggatg
aggagcagcagcgagcactgcagactggccgtctccgttcacaggcacctgcagccttcc
gggaggtacgtcgcccagctgctgccccacaacgaggctggaagagagatcctcctggta
cctactccggggaagcatggctggacagtgctgcagggaagaattgggcgcccagagaac
ccgttccgagtggccctggagtacatttcaagtggaaaccgaagcttgtctgcagtggac
ttctttgccctgaagaactgcagtgaagggacatccccaggctccaagatggccttgcag
agttccttcacttgctggaacgggacagtcctccagctcggccaggcctgcgacttccac
caggactgcgcccagggagaagacgaggaccagctctgcagtaagctccctgctggtttc
tactgcagttttgaggatggcttctgtggctggtcccaaggaacgctctcaccccacgca
cccgagtggcaggtcaagaccctaaaggaggcccggttccaggaccgtcaaggccacgcc
ctgttgctcaacaccacggaggtccccacttctgcaagtgctacagtgaccagcaccaca
ttccccgcaccgatgaagaactctccgtgcgagctccggatgtcctggctcatccaggga
gtcttgaggggaaacgtctccttggtgctggtggagaacagaaccgggaaggagcagagc
aggatggtctggcacgttgccacaaatgaaggcctgagcctgtggcagtggacggtgctg
cccctccttgacgtggctgacaggttctggctgcagattgtcgcatggtggggacaagga
tccagagccaccgtggcttttgacaatatctccatcagcctggactgctacctcaccatc
agtggggaggacaagatgctgcagaatacagcacccaagtcaagaaatctgtttgagaga
aaccccaacaaggagatgaaactctgggaaaatataccaagagagacccccctctttgac
cctacagttcactggctatttaccacgtgtggggccagtgggccccacggccccacgcag
gcccagtgcaacaatgcttaccggaacaccaacctgagcgtggtggtggggagcgagggc
cccctcaagggcatccagacatggaaggtgccagccaccgacacctacagcatctcgggc
tatggagcggctggcgggaaaggcgggaggaacaccatgatgcggtcccacggcgtgtct
gtgctgggcatcttcaacctggagaaggacgacacgctgtacatcctggtcggacagcag
ggggaggacgcctgtcccagcacaaaccgattaatccagaaagtctgcattggagagaac
aacgtgatagaggaagaaatccgcgtgaacagaagcgtgcacgagtgggcaggagggggc
ggcggagggggcggagccacctacgtatttaagatgaaggacggcgtgccagtgcccctg
atcattgcggctggcggaggtggcagggcctacggggccaagacggacacgttccacccc
gagaggctggagaataactcctcggttctagggctcaacggctactccggagccgcaggt
ggtggaggtggctggaatgataacacttccttgctctggtctggaaaatctttgctggag
ggtgccaccggaggacattcctgcccccaggccatgaagaagtgggggtgggagacaaga
gggggtttcggagggggtggaggggggtgctcctcaggtggaggaggcggaggatatata
ggcggcaacgcagcctcagacaatgaccccgagatggacggagaggatggggtgtccttc
atcagtcccctgggcatcctgtacaccccggctttaaaagtgatggaaggccacggggag
gtgaacattaagcactacctaaactgcagccactgcgagggcgacgagtgccacctggac
cccgagagccaccaggtcatctgcttctgcgaccacggcaccgtgctggctgaggacggt
gtctcttgcgttgtgtcgcccaccccagagccccgcctgccactctcactcatcctctcc
gtcgtgacctctgccctcgtggccgccctcgtcctggcgttctctggcatcatgatcgtg
taccgccggaagcaccaggagctgcaagccatgcagatggaactgcagagccccgaatac
aaactgagcaagctccgcacctcaaccatcatgactgactacaaccccaactactgcttt
gccggcaagacctcgtccatcagtgacctgaaggaggtgccacggaaaaacatcaccctc
attcggggtctgggccatggtgcgtttggggaggtgtatgaaggtcaggtgtctggaatg
cccaacgacccgagccccctgcaagtggcggtaaagacgctgcccgaggtgtgttccgag
caggacgagctggatttcctcatggaagccctgatcatcagcaaattcaatcaccagaac
atcgtgcgctgcatcggagtgagtctgcaggccctgccccggttcatcctgctggagctc
atggcgggaggagacctcaagtccttcctccgggagacccgccctcgcccgaaccagccc
tcctccctggccatgctggaccttctgcacgtggcccgggacattgcctgcggctgccag
tacttggaggaaaatcacttcatccaccgggacattgctgccaggaactgcctcttgacc
tgtccgggccctggaagggtagccaagattggagactttggaatggcccgggacatctac
agagcgagctactaccgaaagggcggctgtgcgatgctgcccgtgaagtggatgccccca
gaggccttcatggaaggaatatttacatccaaaacagacacgtggtcctttggagtgctg
ctgtgggaaatattctctcttggatatatgccataccccagcaagagcaaccaggaggtc
ctggagtttgtcaccagcggaggacggatggaccccccgaagaactgccctgggcctgta
tacaggataatgacccagtgctggcagcaccagcccgaggacaggcccaacttcgccatc
atcctggagaggatcgaatactgcacacaggatccagatgtgatcaacacggctttgcca
atagaatacggcccactcgtggaggaggaggagaaagtgcccgtgaggcccaaagaccct
gagggaatccctcctctcttagtctctcccccagcagggaaagggggggacaagcaggac
gcagccgccccagcccctctgccctccacatcctcgggcaaggcagtaaggaagccacca
gcagcagaggttaacgttcgagtggccagagggccggccgtgggagggggacacgttaac
atggcattcgctcagtcgaacccgccgcccgagctgcacaaagtccagcgatcccgaaac
aagccaaccagcctatggaacccaacatacggctcgtggttcacagagaaacctgccagg
aaggcccgccctccagcacagaaggaacccgagaggggaggcccgggacacgggggcggc
cccgtcccgcccagcgctgcagcgggcagagtccccggggccgccctgctcctggagccg
tcctcgctgacggccagcgtgaaggaagtgcccctgttcaggctgcgtcacttcccgtgt
ggcaccgtcaactacggctaccagcagcagggcctgcccctagaggccgccgcccccggg
gccagtcactaccaggacacggccctccagagccagcctgggccctga
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