Duffyella gerundensis: EM595_3234
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Entry
EM595_3234 CDS
T04258
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of MetE and MetF
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ege
Duffyella gerundensis
Pathway
ege00270
Cysteine and methionine metabolism
ege00450
Selenocompound metabolism
ege00670
One carbon pool by folate
ege01100
Metabolic pathways
ege01110
Biosynthesis of secondary metabolites
ege01230
Biosynthesis of amino acids
ege04981
Folate transport and metabolism
Module
ege_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ege00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EM595_3234 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
EM595_3234 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
EM595_3234 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
EM595_3234 (metH)
04980 Cobalamin transport and metabolism
EM595_3234 (metH)
Enzymes [BR:
ege01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
EM595_3234 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
CUU25465
UniProt:
A0A0U5L3T5
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All DBs
Position
1:complement(3490651..3494334)
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AA seq
1227 aa
AA seq
DB search
MSNRIEALRQQLSRRIMLLDGGMGTMIQSYKLSEQDFRGARFADWQSDLQGNNDLLVLTR
PDIISEIHHAYLAAGADILETNTFNATTIAMADYHMESLSAEINFTAAKLARACADEWTA
KTPDRPRYVAGVLGPTNRTCSISPDVNDPAYRNVTFNQLVTAYRESTRALIEGGADLLMI
ETVFDTLNAKAAIFAIQSEQEALGVALPLMISGTITDASGRTLSGQTTEAFYNSLRHAEP
LSFGLNCALGPDELRQYVADLSRLADSYVTAHPNAGLPNAFGEYDLDADIMAEQIGEWAR
AGFLNIVGGCCGTTPQHIAAMARAVDGVAPRTVPTLPVACRLSGLEPLNIGADSLFVNVG
ERTNVTGSAKFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLQCIQGKGIVNSISMKEGVDAFIHHARLVRRYGAAM
VVMAFDEVGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAM
DFIGACEDIKRELPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELREAVEDVVRNRRDDGTERLLDLAEKYRGSKSEDDSTKPQAEWRSWEVD
KRLEYALVKGITEFIEEDTEAARQNASRPIEVIEGPLMSGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPYIEASKAVGSTNGKIVLATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPGEKILRTARELNADIIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDSKHDEFVARTRKEYETVRIQHGRKKPR
TPPVTLQEARDNALPIDWESYTPPVAHRLGVSEVSASIDTLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAQRLFADANALLDTLSTHRSLTPRGVVGIFPANRVGDDIEVYADESRS
QVIQVSYHLRQQTQKTDFANYCLADFVAPKSSGKADYLGAFAVTGGLEEDALAEAYDRQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVIWGFGANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKAAIWQLLDVEAHTGMQLTESFAMWPGASVSGWYFSHPDSKYFAVAQLQRDQI
EDYAARKGMAVGEVERWLAPNLGYDAE
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaatagaattgaagcgctgcgccagcagctgtcccgacgtatcatgctgcttgat
ggcggcatgggcaccatgatccagagctataagctgtcagaacaggattttcgcggtgca
cgttttgctgactggcaaagcgacctgcagggcaataacgatctgctggttctgacgcgt
cccgacatcatcagtgagattcaccacgcttatctggccgcgggcgctgatattctggaa
accaacaccttcaacgccactacgattgcgatggcggattaccatatggaatcgctctct
gctgagataaatttcacagcggcgaagctggcacgtgcctgtgctgatgaatggacagcg
aaaacaccggatcgtccgcggtacgtggcaggcgtattgggtccaaccaatcgtacctgt
tccatttcaccggatgttaacgatcccgcttaccgaaatgtcacgtttaatcagctggta
accgcctatcgtgaatcaacacgcgcgctgattgaaggtggagccgatctccttatgatc
gaaactgtttttgacacgttaaacgccaaagcggccattttcgcgattcagagcgaacag
gaagcgttgggcgtggcgctgccattgatgatttccggcaccatcactgatgcatcaggc
cgtacgctgtctggtcaaactactgaggccttttataactccctgcgtcatgcggaaccg
ctctcctttggcctcaactgcgcgctgggaccggacgaactgcgccagtatgtcgccgat
ctgtcacgccttgccgatagctatgtgacagctcatcccaacgctggcttacccaacgcc
tttggtgaatacgatcttgatgccgatatcatggcagaacagattggtgaatgggcacgg
gcgggctttttgaatatcgttggcggctgctgtggtaccacgccacagcacattgccgcc
atggcgcgcgccgttgacggtgtggcaccgcgtaccgtgccaacgttgccggttgcctgc
cggttgtcgggtctggaacccttgaatatcggcgccgattcgctgtttgtgaacgttggc
gaacgcaccaacgttacgggttcggcaaaatttaagcggctgatcaaagaagagaaatat
aacgaagcgctggatgtagcacgtcagcaggtagaaagcggcgcgcaaatcatagatatc
aacatggatgaaggcatgctggatgctgaagcagccatggtgcgctttctcaacttgatt
gccggtgagccagacatcgcgcgggtgccaatcatgattgactcctcaaagtgggaggtg
attgaaaaagggctgcagtgcattcagggcaagggcatcgtcaactccatctcgatgaaa
gagggcgttgacgcctttatacatcacgcgcggctggtgcgtcgctacggcgctgcgatg
gtcgtaatggcctttgatgaggttggtcaggcggatacccgcgcgcgcaaaatcgagatt
tgccgtcgtgcttataaaattctgactgaagaggtcggttttccgccggaagacatcatc
tttgaccccaatatctttgccgtagccaccggcattgaagagcataataattatgcgatg
gattttatcggcgcctgtgaagatatcaaacgcgaactgccgcatgccatgatttccggc
ggtgtctccaacgtctcattctcctttcgtggcaacgacccggttcgcgaagcgattcac
gccgtcttcctctattacgccattcgcaacggcatggacatgggcatcgtcaacgccggt
cagctggcaatctacgacgatctgcccgccgagctgcgtgaagcggtagaagatgtggtg
cgcaatcgccgggacgatggcaccgaacgcctgttggatttggctgagaaataccgtggc
agcaaaagcgaggatgatagtaccaaaccccaggcggaatggcgcagttgggaggtcgat
aagcggctcgagtatgcgctggtaaaaggcattaccgaatttattgaggaagataccgaa
gcagcgcgccagaacgcctcgcgcccgattgaggtgattgaaggcccgttaatgtccggc
atgaacgtggttggcgatctgttcggcgaaggcaaaatgttcctgccgcaggtggtgaaa
tccgcacgcgtgatgaaacaagcggtggcttatctggagccgtatattgaggccagtaaa
gcggtgggcagcaccaacggcaaaatcgtactggccacggtgaaaggcgacgtacatgac
atcggcaaaaatatcgttggcgtcgtgctgcagtgtaataactatgaaattatcgatctc
ggcgtcatggtgccaggtgaaaaaatcctgcgcactgccagagagctcaacgccgatatc
attgggctttccggcttaattacgccatcgctcgacgagatggttaacgtggccaaagag
atggagcgtcagggttttactatcccgctgctgattggtggtgccaccacctcaaaagcc
cataccgcagtaaaaattgagcagaactacagcggcccaacggtttatgtgcaaaacgct
tcacgcaccgtgggcgtggtttctgcgctgctttccgacagcaaacatgatgagtttgtt
gcccgcacgcgtaaagagtatgaaacggtgcgcattcagcatggacgtaaaaagccgcgc
acgccgccggtgaccttgcaggaagcgcgtgataatgcgttgccgatcgactgggaaagt
tacacgccgccggtagcgcatcgtctcggcgttagcgaagtcagcgccagcattgatacg
ctgcgcaattatatcgactggaccccgttttttatgacctggtcgctggcaggtaaatat
ccgcgcatccttgaggatgaggtcgttggcgaagaggcgcagcggctgtttgccgatgcc
aacgccttgcttgatacgctgtcaacgcatcgcagcctgacgccgcgcggcgttgtcggc
atatttcctgccaaccgcgttggcgacgacatcgaagtttatgccgatgagtcgcgttca
caggtgattcaggtgagctatcacctgcgccagcaaacgcaaaaaaccgacttcgctaat
tactgtctggctgattttgtggcgccgaaatcaagtggtaaagcggattatctgggcgcg
tttgccgttaccggcggtctggaagaggacgcgctggccgaggcgtacgatcgccagcat
gatgattacaacaagatcatggtgaaggcgttagccgatcgcctggcggaagctttcgcg
gaatatctgcatgaacgcgtgcgtaaggtgatctggggctttggtgccaatgaaaatctc
agcaatgaagagttgattcgcgaaaattatcagggtattcgtccggcgccgggttatccc
gcctgtcctgaacatactgagaaagcggctatctggcagctgctggacgtcgaggcgcat
accggcatgcagctgacagaatctttcgcgatgtggcctggtgcgtcggtttccggctgg
tacttcagccatcctgacagtaaatactttgccgttgctcagctgcagcgcgatcagatt
gaagattacgcggcgcgtaaggggatggcggtaggtgaagtggagcgctggctagcaccg
aatttgggttacgatgcggagtga
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